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Summary of Significant Accounting Policies (Tables)

6 Months Ended

Jun. 30, 2021

Accounting Policies [Abstract]

Schedule of Carrying Value and Fair Value of Assets and Liabilities

The following table shows assets and liabilities that are measured at fair value on a recurring basis and their carrying value (in millions):

			June 30, 2021
									Fair Value
			Carrying Value						Level 1						Level 2						Level 3
Cash and cash equivalents			$	928.3					$	928.3					$	—					$	—

			December 31, 2020
									Fair Value
			Carrying Value						Level 1						Level 2						Level 3
Cash and cash equivalents			$	532.8					$	532.8					$	—					$	—

Reconciliation of the Weighted Average Number of Shares Used to Compute Basic and Diluted Net Loss per Share

The following table sets forth the reconciliation of the weighted average number of common shares used to compute basic and diluted net loss per share for the three and six months ended June 30, 2021 and 2020:

 

			Three Months Ended June 30,												Six Months Ended June 30,
			2021						2020						2021						2020
			(in thousands, except per share amounts)
Numerator:
Net loss			$	(117,321)					$	(61,854)					$	(208,962)					$	(128,218)
Denominator:
Weighted average common shares used in calculation of basic net loss per share:			109,580						96,633						106,328						93,206
Effect of dilutive securities:
Common stock options			—						—						—						—
Restricted stock and RSUs			—						—						—						—
Convertible debt securities			—						—						—						—
Weighted average common shares outstanding used in calculation of diluted net loss per share			109,580						96,633						106,328						93,206
Net loss per share:
Basic and diluted			$	(1.07)					$	(0.64)					$	(1.97)					$	(1.38)

Potentially Dilutive Securities Excluded from Computations of Diluted Weighted Average Common Shares Outstanding

The following potentially dilutive securities have been excluded from the computations of diluted weighted average common shares outstanding as of June 30, 2021 and 2020 as their effect would have been anti-dilutive (in thousands):

 

			June 30,
			2021						2020
Common stock options			14,449						13,272
Unvested restricted stock and RSUs			1,125						868
Convertible debt securities			23,438						11,492

Schedule of Percentage of Total Gross Product Revenue Represented by the Three Largest Customers

The following table presents the percentage of total gross product revenue represented by the Company's three largest customers for the six months ended June 30, 2021 and 2020.

			June 30,
			2021						2020
Customer A			30%						26%
Customer B			25%						27%
Customer C			23%						25%

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Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities.

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Tabular disclosure of assets and liabilities, including [financial] instruments measured at fair value that are classified in stockholders' equity, if any, that are measured at fair value on a recurring basis. The disclosures contemplated herein include the fair value measurements at the reporting date by the level within the fair value hierarchy in which the fair value measurements in their entirety fall, segregating fair value measurements using quoted prices in active markets for identical assets (Level 1), significant other observable inputs (Level 2), and significant unobservable inputs (Level 3).

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