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The Company and Basis of Presentation (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Dec. 31, 2021
Organization, Consolidation and Presentation of Financial Statements [Abstract]          
Cash and cash equivalents $ 416,078   $ 416,078   $ 716,782
Marketable securities 148,600   148,600    
Net loss $ (95,645) $ (117,321) $ (190,266) $ (208,962)