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Summary of Significant Accounting Policies - Anti-dilutive Securities (Details) - shares
shares in Thousands
6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Common stock options    
Anti-dilutive securities excluded from computations of diluted weighted-average common shares outstanding    
Potentially dilutive securities excluded from computations of diluted weighted-average shares outstanding (in shares) 17,806 14,449
Unvested restricted stock and RSUs    
Anti-dilutive securities excluded from computations of diluted weighted-average common shares outstanding    
Potentially dilutive securities excluded from computations of diluted weighted-average shares outstanding (in shares) 1,619 1,125
PSUs    
Anti-dilutive securities excluded from computations of diluted weighted-average common shares outstanding    
Potentially dilutive securities excluded from computations of diluted weighted-average shares outstanding (in shares) 670 0
Convertible debt securities    
Anti-dilutive securities excluded from computations of diluted weighted-average common shares outstanding    
Potentially dilutive securities excluded from computations of diluted weighted-average shares outstanding (in shares) 23,438 23,438