<SEC-DOCUMENT>0001140361-23-025755.txt : 20230519
<SEC-HEADER>0001140361-23-025755.hdr.sgml : 20230519
<ACCEPTANCE-DATETIME>20230519162227
ACCESSION NUMBER:		0001140361-23-025755
CONFORMED SUBMISSION TYPE:	S-8
PUBLIC DOCUMENT COUNT:		5
FILED AS OF DATE:		20230519
DATE AS OF CHANGE:		20230519
EFFECTIVENESS DATE:		20230519

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			INSMED Inc
		CENTRAL INDEX KEY:			0001104506
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				541972729
		STATE OF INCORPORATION:			VA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-8
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-272091
		FILM NUMBER:		23940427

	BUSINESS ADDRESS:	
		STREET 1:		700 US HIGHWAY 202/206
		CITY:			BRIDGEWATER
		STATE:			NJ
		ZIP:			08807
		BUSINESS PHONE:		908-977-9900

	MAIL ADDRESS:	
		STREET 1:		700 US HIGHWAY 202/206
		CITY:			BRIDGEWATER
		STATE:			NJ
		ZIP:			08807

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	INSMED INC
		DATE OF NAME CHANGE:	20000128
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-8
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<DESCRIPTION>S-8
<TEXT>
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      <hr style="border: none; border-bottom: 1px solid black; border-top: 4px solid black; height: 10px; color: #ffffff; background-color: #ffffff; margin-left: auto; margin-right: auto;" align="center">As filed with the Securities and Exchange Commission
      on May 19, 2023</div>
    <div style="text-align: right; color: #000000; font-weight: bold;">Registration No. 333-</div>
    <div>
      <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
    </div>
    <div style="text-align: center; color: #000000; font-size: 8pt; font-weight: bold;">&#160;</div>
    <div style="text-align: center; color: #000000; font-size: 18pt; font-weight: bold;">SECURITIES AND EXCHANGE COMMISSION</div>
    <div style="text-align: center; color: #000000; font-weight: bold;">Washington, D.C. 20549</div>
    <div style="color: #000000; font-size: 8pt;">&#160;</div>
    <div style="text-align: center; color: #000000; font-size: 18pt; font-weight: bold;">FORM S-8</div>
    <div style="color: #000000; font-size: 8pt;">&#160;</div>
    <div style="text-align: center; color: #000000; font-size: 12pt; font-weight: bold;">REGISTRATION STATEMENT</div>
    <div style="text-align: center; color: #000000; font-size: 12pt; font-weight: bold;">UNDER</div>
    <div style="text-align: center; color: #000000; font-size: 12pt; font-weight: bold;">THE SECURITIES ACT OF 1933</div>
    <div style="color: #000000; font-size: 8pt; font-weight: bold;">&#160;</div>
    <div style="text-align: center; color: #000000; font-size: 18pt; font-weight: bold;">INSMED INCORPORATED</div>
    <div style="text-align: center;">(Exact name of registrant as specified in its charter)</div>
    <div style="color: #000000; font-size: 8pt;">&#160;</div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z72941105ce0e451284c103e6b3340ca9" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center; color: #000000; font-weight: bold;">Virginia</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 2%; vertical-align: bottom;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center; color: #000000; font-weight: bold;">54-1972729</div>
            <div style="color: #000000;">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center;">(State or other jurisdiction of incorporation or<br>
              organization)</div>
          </td>
          <td style="width: 2%; vertical-align: bottom;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 49%; vertical-align: top;">
            <div style="text-align: center;">(I.R.S. Employer Identification No.)</div>
            <div style="color: #000000;">&#160;</div>
          </td>
        </tr>

    </table>
    <div style="color: #000000; font-size: 8pt;">&#160;</div>
    <div style="text-align: center; color: #000000; font-weight: bold;">700 US Highway 202/206<br>
      Bridgewater, New Jersey 08807</div>
    <div style="text-align: center;">(Address of Principal Executive Offices including zip code)</div>
    <div style="color: #000000; font-size: 8pt;">&#160;</div>
    <div style="text-align: center; color: #000000; font-weight: bold;">Insmed Incorporated Amended and Restated 2019 Incentive Plan</div>
    <div style="text-align: center; color: #000000; font-weight: bold;">Insmed Incorporated Non-Qualified Stock Option Inducement Awards</div>
    <div style="text-align: center;">(Full title of the plans)</div>
    <div style="color: #000000; font-size: 8pt;">&#160;</div>
    <div style="text-align: center; color: #000000; font-weight: bold;">Michael A. Smith, Esq.</div>
    <div style="text-align: center; color: #000000; font-weight: bold;">Insmed Incorporated<br>
      General Counsel, Senior Vice President</div>
    <div style="text-align: center; color: #000000; font-weight: bold;">700 US Highway 202/206</div>
    <div style="text-align: center; color: #000000; font-weight: bold;">Bridgewater, New Jersey 08807</div>
    <div style="text-align: center; color: #000000; font-weight: bold;">(908) 977-9900</div>
    <div style="text-align: center;">(Name, address, including zip code, and telephone number, including area code, of agent for service)</div>
    <div style="color: #000000; font-size: 8pt;">&#160;</div>
    <div style="text-align: center; color: #000000; font-weight: bold;">Copies of all communications, including all communications sent to the agent for service, should be sent to:</div>
    <div style="color: #000000; font-size: 8pt;">&#160;</div>
    <div style="text-align: center; color: #000000; font-weight: bold;">Michael J. Riella, Esq.</div>
    <div style="text-align: center;">Covington &amp; Burling LLP</div>
    <div style="text-align: center;">One CityCenter<br>
      850 Tenth St. NW<br>
      Washington, DC 20001<br>
      (202) 662-6000</div>
    <div style="color: #000000; font-size: 8pt;">&#160;</div>
    <div>Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See definitions of &#8220;large accelerated filer,&#8221; &#8220;accelerated
      filer,&#8221; &#8220;smaller reporting company,&#8221; and &#8220;emerging growth company&#8221; in Rule 12b-2 of the Exchange Act:</div>
    <div style="color: #000000; font-size: 8pt;">&#160;</div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z8f1d20225fc145ba960a207406a491ec" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 17.97%; vertical-align: top;">
            <div>Large accelerated filer &#9746;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 2.53%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 23.98%; vertical-align: top;">
            <div>Accelerated filer &#9744;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 2.53%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 23.98%; vertical-align: top;">
            <div>Non-accelerated filer &#9744;</div>
          </td>
          <td style="width: 2.53%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 23.95%; vertical-align: top;">
            <div>Smaller reporting company &#9744;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 2.53%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 17.97%; vertical-align: top;">&#160;</td>
          <td style="width: 2.53%; vertical-align: top;">&#160;</td>
          <td style="width: 23.98%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 2.53%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 23.98%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 2.53%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 23.95%; vertical-align: top;">
            <div>Emerging Growth Company &#9744;</div>
          </td>
          <td style="width: 2.53%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <div>If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the
      Securities Act. &#9744;
      <hr style="border: none; border-bottom: 4px solid black; border-top: 1px solid black; height: 10px; color: #ffffff; background-color: #ffffff; text-align: center; margin-left: auto; margin-right: auto;" align="center"></div>
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      <div class="BRPFPageBreak" style="page-break-after: always;">
        <hr style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;" noshade="noshade"></div>
    </div>
    <div style="text-align: center; color: #000000; font-weight: bold;">&#160;PART I</div>
    <div>&#160;</div>
    <div style="text-align: center; color: #000000; font-weight: bold;">INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS</div>
    <div>&#160;</div>
    <div>
      <table class="DSPFListTable" id="zae970234b10d40e393d13d5b1e352813" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 36pt;">
              <div style="text-align: left;"><font style="font-weight: bold; color: #000000;">Item 1.<br>
                </font></div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;"><font style="color: #000000;"><font style="font-weight: bold;">Plan Information.</font></font></div>
              <div style="text-align: left;"><font style="color: #000000;"><font style="font-weight: bold;"> <br>
                  </font></font></div>
              <div style="text-align: left;">
                <div style="text-indent: 0px;">Not required to be filed as part of this Registration Statement pursuant to the Note to Part I of Form S-8.</div>
                <font style="color: #000000;"><font style="font-weight: bold;"> </font></font></div>
            </td>
          </tr>

      </table>
    </div>
    <div>&#160;</div>
    <div>
      <table class="DSPFListTable" id="z6a25a8ac16ff4330abcdb4b87cb968d7" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 36pt;">
              <div style="text-align: left;"><font style="font-weight: bold; color: #000000;">Item 2.<br>
                </font></div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;"><font style="color: #000000; font-weight: bold;">Registrant Information and Employee Plan Annual Information.</font></div>
              <div style="text-align: left;"><font style="color: #000000; font-weight: bold;"> <br>
                </font></div>
              <div style="text-align: left;">
                <div style="text-indent: 0px;">Not required to be filed as part of this Registration Statement pursuant to the Note to Part I of Form S-8.</div>
                <font style="color: #000000; font-weight: bold;"> </font></div>
            </td>
          </tr>

      </table>
    </div>
    <div>&#160;<br>
    </div>
    <div style="text-align: center; color: #000000; font-weight: bold;">&#160;PART II</div>
    <div>&#160;</div>
    <div style="text-align: center; color: #000000; font-weight: bold;">INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</div>
    <div>&#160;</div>
    <div>
      <table class="DSPFListTable" id="z546a5d8b59444262a0647431d31f729a" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 36pt;">
              <div style="text-align: left;"><font style="font-weight: bold; color: #000000;">Item 3.<br>
                </font></div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;"><font style="color: #000000; font-weight: bold;">Incorporation of Documents by Reference.</font></div>
            </td>
          </tr>

      </table>
    </div>
    <div>&#160;</div>
    <div style="text-indent: 36pt;">The following documents, which have previously been filed by the Registrant with the Securities and Exchange Commission (the &#8220;Commission&#8221;), are incorporated by reference herein and shall be deemed to be a part hereof:</div>
    <div>&#160;</div>
    <div>
      <div>
        <div style="text-indent: 18pt;"><font style="text-indent: 18pt;">(1) </font>The Registrant<font style="color: #000000;">&#8217;</font>s <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/0001104506/000110450623000009/insm-20221231.htm">Annual
            Report on Form 10-K for the year ended December 31, 2022</a>, filed with the Commission on February 23, 2023;</div>
      </div>
    </div>
    <div><br>
    </div>
    <div>
      <div>
        <div style="text-indent: 18pt;"><font style="text-indent: 18pt;">(2) </font>The Registrant&#8217;s <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/0001104506/000110450623000012/insm-20230331.htm">Quarterly Report on Form 10-Q for the quarter
            ended March 31, 2023</a>, filed with the Commission on May 4, 2023;</div>
      </div>
    </div>
    <div><br>
    </div>
    <div>
      <div>
        <div style="text-indent: 18pt;"><font style="text-indent: 18pt;">(3) </font>The Registrant&#8217;s Current Report on Form 8-K, filed with the Commission on <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/0001104506/000114036123024132/brhc20052827_8k.htm">May 11, 2023</a>; and</div>
      </div>
    </div>
    <div><br>
    </div>
    <div>
      <div>
        <div style="text-indent: 18pt;"><font style="text-indent: 18pt;">(4) </font><a href="https://www.sec.gov/Archives/edgar/data/1104506/000091664100000789/0000916641-00-000789-0001.txt">Description of the Registrant&#8217;s common stock contained in its
            registration statement on Form 8-A, dated June 1, 2000</a>, as updated by the Description of Securities Registered Under Section 12 of the Securities Exchange Act of 1934, as amended (the &#8220;Exchange Act&#8221;), filed as <a href="https://www.sec.gov/Archives/edgar/data/1104506/000110450621000005/insm20201231ex45.htm">Exhibit 4.5 to the Registrant&#8217;s Annual Report on Form 10-K for the year ended December 31, 2020</a>, and including any amendment or report
          subsequently filed for the purpose of updating such description.</div>
      </div>
    </div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">In addition, subsequent to the date of this Registration Statement and prior to the filing of a post-effective amendment hereto that indicates all securities offered hereunder have been sold or deregisters all securities
      then remaining unsold, all reports and other documents filed by the Registrant pursuant to Section 13(a), 13(c), 14 or 15(d) of the Exchange Act shall be deemed to be incorporated by reference herein and to be a part hereof from the date of filing of
      such documents; <font style="font-style: italic;">provided, however</font>, that no information furnished (but not filed) under Item 2.02 or Item 7.01 of any Current Report on Form 8-K shall be incorporated by reference except to the extent
      specified in such Current Report on Form 8-K.</div>
    <div>&#160;</div>
    <div style="text-indent: 38.25pt;">For purposes of this Registration Statement, any statement contained in a document incorporated or deemed to be incorporated herein by reference shall be deemed to be modified or superseded to the extent that a
      statement contained herein or in any subsequently filed document that also is incorporated or is deemed to be incorporated herein by reference modifies or supersedes such statement. Any statement so modified or superseded shall not be deemed, except
      as so modified or superseded, to constitute a part of this Registration Statement.</div>
    <div>&#160;</div>
    <div>
      <table class="DSPFListTable" id="z1b7d70abf0c2444b9f32d2c81239ca53" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 36pt;">
              <div style="text-align: left;"><font style="font-weight: bold; color: #000000;">Item 4.<br>
                </font></div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;"><font style="color: #000000; font-weight: bold;">Description of Securities.</font></div>
              <div style="text-align: left;"><font style="color: #000000; font-weight: bold;"> <br>
                </font></div>
              <div style="text-align: left;">
                <div style="text-indent: 0px;">Not applicable.</div>
                <font style="color: #000000; font-weight: bold;"> </font></div>
            </td>
          </tr>

      </table>
    </div>
    <div>&#160;</div>
    <div>
      <table class="DSPFListTable" id="z0d5e46792d804cad96c18233857736dc" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 36pt;">
              <div style="text-align: left;"><font style="font-weight: bold; color: #000000;">Item 5.<br>
                </font></div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;"><font style="color: #000000; font-weight: bold;">Interests of Named Experts and Counsel.</font></div>
              <div style="text-align: left;"><font style="color: #000000; font-weight: bold;"> <br>
                </font></div>
              <div style="text-align: left;">
                <div style="text-indent: 0px;">Not applicable.</div>
                <font style="color: #000000; font-weight: bold;"> </font></div>
            </td>
          </tr>

      </table>
    </div>
    <div style="text-indent: 36pt;">&#160;<br>
    </div>
    <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
      <div class="BRPFPageBreak" style="page-break-after: always;">
        <hr style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;" noshade="noshade"></div>
    </div>
    <div>
      <table class="DSPFListTable" id="za5d4dc68ffd544e6b3c9c249864c4102" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 36pt;">
              <div style="text-align: left;"><font style="font-weight: bold; color: #000000;">Item 6.<br>
                </font></div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;"><font style="color: #000000; font-weight: bold;">Indemnification of Directors and Officers.</font></div>
            </td>
          </tr>

      </table>
    </div>
    <div>&#160;</div>
    <div style="text-indent: 36pt;">The Virginia Stock Corporation Act (the &#8220;VSCA&#8221;) permits, and the Registrant&#8217;s Articles of Incorporation require, indemnification of the Registrant&#8217;s directors and officers in a variety of circumstances, which may include
      indemnification for liabilities under the Securities Act. Under the VSCA, a Virginia corporation is generally authorized to indemnify its directors and officers in civil or criminal actions if they acted in good faith and believed their conduct to be
      in the best interests of the corporation and, in the case of criminal actions, had no reasonable cause to believe that the conduct was unlawful, or if they engaged in conduct for which broader indemnification has been made permissible or obligatory
      by the Registrant. The VSCA requires such indemnification, unless limited by a corporation&#8217;s articles of incorporation, when a director or officer entirely prevails in the defense of any proceeding to which he or she was a party because he or she is
      or was a director or officer of the corporation. The VSCA provides that a corporation may make any other or further indemnity (including indemnity with respect to a proceeding by or in the right of the corporation), and may make additional provision
      for advances and reimbursement of expenses, if authorized by its articles of incorporation or shareholder-adopted bylaw or resolution, except an indemnity against willful misconduct or a knowing violation of the criminal law. The Registrant&#8217;s
      Articles of Incorporation require indemnification of directors and officers with respect to certain liabilities, expenses and other amounts imposed upon them because of having been a director or officer, except in the case of willful misconduct or a
      knowing violation of criminal law.</div>
    <div>&#160;</div>
    <div style="text-indent: 36pt;">The VSCA establishes a statutory limit on liability of directors and officers of a corporation for damages assessed against them in a suit brought by or in the right of the corporation or brought by or on behalf of the
      corporation&#8217;s shareholders and authorizes a corporation to specify a lower monetary limit on liability (including the elimination of liability for monetary damages) in the corporation&#8217;s articles of incorporation or shareholder-approved bylaws;
      however, the liability of a director or officer shall not be limited if such director or officer engaged in willful misconduct or a knowing violation of the criminal law or of any federal or state securities law, including, without limitation, any
      unlawful insider trading or manipulation of the market for any security. As permitted by the VSCA, the Registrant&#8217;s Articles of Incorporation provide that no director or officer of the Registrant shall be liable to the Registrant or the Registrant&#8217;s
      shareholders for monetary damages with respect to any transaction, occurrence or course of conduct, except for liability resulting from such person&#8217;s having engaged in willful misconduct or a knowing violation of the criminal law or any federal or
      state securities law.</div>
    <div>&#160;</div>
    <div style="text-indent: 36pt;">Certain directors and officers have been granted contractual indemnification rights under separate indemnification agreements with the Registrant, pursuant to which they will be entitled to indemnification from the
      Registrant under certain circumstances. Additionally, the employment agreements the Registrant has entered into with its executive officers provide for indemnification to the fullest extent permitted by law from and against any and all claims,
      damages, expenses (including attorneys&#8217; fees), judgments, penalties, fines, settlements, and all other liabilities incurred or paid by the executive officer in connection with the investigation, defense, prosecution, settlement or appeal of any
      threatened, pending or completed action, suit or proceeding, whether civil, criminal, administrative or investigative in nature, and to which the executive officer was or is a party or is threatened to be made a party by reason of the fact that he or
      she is or was an officer, employee or agent of the Registrant, or by reason of anything done or not done by him or her in any such capacity or capacities, provided that such executive officer acted in good faith, in a manner that was not grossly
      negligent or that constituted willful misconduct and in a manner he or she reasonably believed to be in or not opposed to the Registrant&#8217;s best interests, and, with respect to any criminal action or proceeding, had no reasonable cause to believe his
      or her conduct was unlawful. The Registrant also carries insurance on behalf of directors, officers, employees or agents that may cover liabilities under the Securities Act.</div>
    <div>&#160;</div>
    <div>
      <table class="DSPFListTable" id="z9a43fd105076432e8f976ad448f48126" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 36pt;">
              <div style="text-align: left; text-indent: 2.25pt;"><font style="font-weight: bold; color: #000000;">Item 7.<br>
                </font></div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left; text-indent: 0px;"><font style="color: #000000;"><font style="font-family: 'Times New Roman', serif; font-size: 3pt;">&#160;</font><font style="font-weight: bold;">Exemption From Registration Claimed.</font></font></div>
              <div style="text-align: left; text-indent: 0px;"><font style="color: #000000;"><font style="font-weight: bold;"> <br>
                  </font></font></div>
              <div style="text-align: left; text-indent: 0px;">Not applicable.<font style="color: #000000;"><font style="font-weight: bold;"> </font></font></div>
            </td>
          </tr>

      </table>
    </div>
    <div>&#160;</div>
    <div>
      <table class="DSPFListTable" id="zc78164bd0fe843e685e0c157f2d09af9" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 36pt;">
              <div style="text-align: left;"><font style="font-weight: bold; color: #000000;">Item 8.<br>
                </font></div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;">
              <div style="text-align: left;"><font style="color: #000000;"><font style="font-family: 'Times New Roman', serif; font-size: 3pt;">&#160;</font><font style="font-weight: bold;">Exhibits.</font></font></div>
              <div style="text-align: left;"><font style="color: #000000;"><font style="font-weight: bold;"> <br>
                  </font></font></div>
              <div style="text-align: left;">A list of exhibits included in this Registration Statement is set forth on the Exhibit Index and is incorporated herein by reference.<font style="color: #000000;"><font style="font-weight: bold;"> </font></font></div>
            </td>
          </tr>

      </table>
    </div>
    <div>&#160;</div>
    <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
      <div class="BRPFPageBreak" style="page-break-after: always;">
        <hr style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;" noshade="noshade"></div>
    </div>
    <div>
      <table class="DSPFListTable" id="ze6c92cbddcf84868a9e149ca722c9503" style="width: 100%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" cellpadding="0" cellspacing="0">

          <tr style="vertical-align: top;">
            <td style="vertical-align: top; width: 36pt;">
              <div style="margin: 0px 0px 0px 0px; color: #000000; text-align: left; text-indent: 0px;"><font style="font-weight: bold;">Item 9.</font> <br>
              </div>
            </td>
            <td style="align: left; vertical-align: top; width: auto;"><font style="font-weight: bold;">Undertakings.</font></td>
          </tr>

      </table>
    </div>
    <div>&#160;</div>
    <div>(a)<font style="color: #000000;">&#160;</font>The undersigned Registrant hereby undertakes:</div>
    <div>&#160;</div>
    <div style="text-indent: 36pt;">(1)<font style="color: #000000;">&#160;</font>To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:</div>
    <div>&#160;</div>
    <div style="text-indent: 72pt;">(i)<font style="color: #000000;">&#160;</font>To include any prospectus required by Section 10(a)(3) of the Securities Act;</div>
    <div>&#160;</div>
    <div style="text-indent: 72pt;">(ii)<font style="color: #000000;">&#160;</font>To reflect in the prospectus any facts or events arising after the effective date of the Registration Statement (or the most recent post-effective amendment thereof) which,
      individually or in the aggregate, represent a fundamental change in the information set forth in the Registration Statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of
      securities offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in the
      aggregate, the changes in volume and price represent no more than 20 percent change in the maximum aggregate offering price set forth in the <font style="color: #000000;">&#8220;</font>Calculation of Registration Fee<font style="color: #000000;">&#8221;</font>
      table in the effective registration statement; and</div>
    <div>&#160;</div>
    <div style="text-indent: 72pt;">(iii)<font style="color: #000000;">&#160;</font>To include any material information with respect to the plan of distribution not previously disclosed in the Registration Statement or any material change to such information in
      the Registration Statement;&#160;</div>
    <div><font style="font-style: italic; color: #000000;"> </font><br>
    </div>
    <div><font style="font-style: italic; color: #000000;">provided, however</font><font style="color: #000000;">,</font> that paragraphs (a)(1)(i) and (a)(1)(ii) do not apply if the information required to be included in a post-effective amendment by
      those paragraphs is contained in reports filed with or furnished to the Commission by the Registrant pursuant to Section 13 or Section 15(d) of the Exchange Act that are incorporated by reference in the Registration Statement;</div>
    <div>&#160;</div>
    <div style="text-indent: 36pt;">(2)<font style="color: #000000;">&#160;</font>That, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating to the
      securities offered therein, and the offering of such securities at that time shall be deemed to be the initial <font style="font-style: italic; color: #000000;">bona fide</font> offering thereof; and</div>
    <div>&#160;</div>
    <div style="text-indent: 36pt;">(3)<font style="color: #000000;">&#160;</font>To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.</div>
    <div>&#160;</div>
    <div>(b)<font style="color: #000000;">&#160;</font>The undersigned Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of the Registrant<font style="color: #000000;">&#8217;</font>s annual report
      pursuant to Section 13(a) or Section 15(d) of the Exchange Act (and, where applicable, each filing of an employee benefit plan<font style="color: #000000;">&#8217;</font>s annual report pursuant to Section 15(d) of the Exchange Act) that is incorporated by
      reference in the Registration Statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial <font style="font-style: italic; color: #000000;">bona fide</font> offering thereof.</div>
    <div>&#160;</div>
    <div>(c)<font style="color: #000000;">&#160;</font>Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the Registrant pursuant to the foregoing provisions, or
      otherwise, the Registrant has been advised that in the opinion of the Commission such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification against
      such liabilities (other than the payment by the Registrant of expenses incurred or paid by a director, officer or controlling person of the Registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer
      or controlling person in connection with the securities being registered, the Registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question
      whether such indemnification by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.</div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
      <div style="page-break-after: always;" class="BRPFPageBreak">
        <hr style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;" noshade="noshade"></div>
    </div>
    <div style="text-align: center; color: #000000; font-weight: bold;">EXHIBIT INDEX</div>
    <div>&#160;</div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z605651c186ba4655b706cbe1ccf20568" border="0" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 8%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="color: #000000; font-size: 8pt; font-weight: bold;">Exhibit No.</div>
            <div style="color: #000000; font-size: 8pt; font-weight: bold;"> <br>
            </div>
          </td>
          <td style="width: 2%; vertical-align: bottom;">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt; font-weight: bold;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 90%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-size: 8pt; font-weight: bold;">Exhibit Description</div>
            <div style="text-align: center; color: #000000; font-size: 8pt; font-weight: bold;"> <br>
            </div>
          </td>
        </tr>
        <tr>
          <td style="width: 8%; vertical-align: top; background-color: rgb(255, 255, 255); color: rgb(0, 0, 0);">
            <div style="font-family: 'Times New Roman',Times,serif;"><a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/0001104506/000114036123015322/ny20006571x1_def14a.htm#a021">4.1</a></div>
          </td>
          <td style="width: 2%; vertical-align: bottom;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 90%; vertical-align: top;">
            <div>Insmed Incorporated Amended and Restated 2019 Incentive Plan (incorporated by reference from Appendix A to Insmed Incorporated&#8217;s Proxy Statement on Schedule 14A, filed on March 31, 2023).<font style="color: #000000;">&#160;</font></div>
          </td>
        </tr>
        <tr>
          <td style="width: 8%; vertical-align: top; background-color: rgb(255, 255, 255); color: rgb(0, 0, 0);">&#160;</td>
          <td style="width: 2%; vertical-align: bottom;">&#160;</td>
          <td style="width: 90%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 8%; vertical-align: top; background-color: rgb(255, 255, 255); color: rgb(0, 0, 0);">
            <div style="font-family: 'Times New Roman',Times,serif;"><a href="https://www.sec.gov/Archives/edgar/data/1104506/000110450623000012/insm-20230331ex101.htm">4.2</a></div>
          </td>
          <td style="width: 2%; vertical-align: bottom;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 90%; vertical-align: top;">
            <div>Form of Insmed Incorporated Non-Qualified Stock Option Inducement Award Agreement (incorporated by reference from Exhibit 10.1 to Insmed Incorporated&#8217;s Quarterly Report on Form 10-Q, filed on May 4, 2023).</div>
          </td>
        </tr>
        <tr>
          <td rowspan="1" style="width: 8%; vertical-align: top; background-color: rgb(255, 255, 255); color: rgb(0, 0, 0);">&#160;</td>
          <td rowspan="1" style="width: 2%; vertical-align: bottom;">&#160;</td>
          <td rowspan="1" style="width: 90%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 8%; vertical-align: top; background-color: rgb(255, 255, 255); color: rgb(0, 0, 0);">
            <div style="font-family: 'Times New Roman',Times,serif;"><a href="https://www.sec.gov/Archives/edgar/data/1104506/000110450623000012/insm-20230321ex102.htm">4.3</a></div>
          </td>
          <td style="width: 2%; vertical-align: bottom;">&#160;</td>
          <td style="width: 90%; vertical-align: top;">Form of Insmed Incorporated Non-Qualified Stock Option Inducement Award Agreement for non-U.S. employees (incorporated by reference from Exhibit 10.2 to Insmed Incorporated&#8217;s Quarterly Report on Form
            10-Q, filed on May 4, 2023).</td>
        </tr>
        <tr>
          <td style="width: 8%; vertical-align: top; background-color: rgb(255, 255, 255); color: rgb(0, 0, 0);">&#160;</td>
          <td style="width: 2%; vertical-align: bottom;">&#160;</td>
          <td style="width: 90%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 8%; vertical-align: top;">
            <div><a href="ny20009120x2_ex5-1.htm">5.1*</a></div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 2%; vertical-align: bottom;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 90%; vertical-align: top;">
            <div>Opinion of Hunton Andrews Kurth LLP.</div>
            <div style="color: #000000;">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 8%; vertical-align: top;">
            <div><a href="ny20009120x2_ex5-1.htm">23.1*</a></div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 2%; vertical-align: bottom;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 90%; vertical-align: top;">
            <div>Consent of Hunton Andrews Kurth LLP (included in Exhibit 5.1).</div>
            <div style="color: #000000;">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 8%; vertical-align: top;">
            <div><a href="ny20009120x2_ex23-2.htm">23.2</a>*</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 2%; vertical-align: bottom;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 90%; vertical-align: top;">
            <div>Consent of Ernst &amp; Young LLP, Independent Registered Public Accounting Firm.</div>
            <div style="color: #000000;">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 8%; vertical-align: top;">
            <div><a href="#POWEROFATTORNEY">24.1</a></div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 2%; vertical-align: bottom;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 90%; vertical-align: top;">
            <div>Power of Attorney (included on signature page hereto).</div>
            <div style="color: #000000;">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 8%; vertical-align: top;">
            <div><a href="ny20009120x2_ex107.htm">107</a>*</div>
          </td>
          <td style="width: 2%; vertical-align: bottom;">&#160;</td>
          <td style="width: 90%; vertical-align: top;">
            <div>Filing Fee Table.</div>
          </td>
        </tr>

    </table>
    <div>&#160; <br>
      <hr style="background-color: #000000; border: 0px; height: 1px; width: 2in; margin-left: 0pt; margin-right: auto; color: #000000;" align="left" noshade="noshade"></div>
    <div>* Filed herewith.</div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
      <div style="page-break-after: always;" class="BRPFPageBreak">
        <hr style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;" noshade="noshade"></div>
    </div>
    <div style="text-align: center; color: #000000; font-weight: bold;">SIGNATURES</div>
    <div>&#160;</div>
    <div style="text-indent: 36pt;">Pursuant to the requirements of the Securities Act, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration
      Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Bridgewater, State of New Jersey, on May 19, 2023.</div>
    <div style="text-align: center;">&#160;</div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z9b2ce656204944218abf21c3e8e692c2" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 49.94%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td colspan="2" style="width: 50.06%; vertical-align: top;">
            <div style="color: #000000; font-weight: bold;">INSMED INCORPORATED</div>
          </td>
        </tr>
        <tr>
          <td style="width: 49.94%; vertical-align: top;">
            <div>&#160;</div>
          </td>
          <td style="width: 5.03%; vertical-align: top;"><br>
          </td>
          <td style="width: 45.03%; vertical-align: top;"><br>
          </td>
        </tr>
        <tr>
          <td style="width: 49.94%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 5.03%; vertical-align: top;">
            <div>By:</div>
          </td>
          <td style="width: 45.03%; vertical-align: top; border-bottom: #000000 2px solid;">/s/ William H. Lewis <br>
          </td>
        </tr>
        <tr>
          <td style="width: 49.94%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 5.03%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 45.03%; vertical-align: top;">
            <div>William H. Lewis</div>
          </td>
        </tr>
        <tr>
          <td style="width: 49.94%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 5.03%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 45.03%; vertical-align: top;">
            <div>Chairman, President and Chief Executive Officer</div>
            <div style="color: #000000;">&#160;</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <div style="text-align: center; color: #000000; font-weight: bold;"><a name="POWEROFATTORNEY"><!--Anchor--></a>POWER OF ATTORNEY</div>
    <div>&#160;</div>
    <div style="text-indent: 36pt;">KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Michael A. Smith his or her true and lawful attorney with power of substitution and resubstitution to sign in
      his or her name, place and stead in any and all such capacities the Registration Statement and any and all amendments and supplements thereto (including post-effective amendments) and documents in connection therewith, and to file the same with the
      Commission, said attorney to have full power and authority to do and perform, in the name of and on behalf of each of said officers and directors of the Registrant who shall have executed such a power of attorney, every act whatsoever which such
      attorney may deem necessary or desirable to be done in connection therewith, as fully and to all intents and purposes as such officer or director of the Registrant might or could do in person.</div>
    <div>&#160;</div>
    <div style="text-indent: 36pt;">Pursuant to the requirements of the Securities Act, this Registration Statement has been signed by the following persons in the capacities and on the dates indicated.</div>
    <div>&#160;</div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="zef478f2e87514072a175ae7d10aef6b6" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 28%; vertical-align: bottom; border-bottom: #000000 2px solid;">
            <div style="text-align: center; color: #000000; font-size: 8pt; font-weight: bold;">Signature</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 2%; vertical-align: bottom;">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt; font-weight: bold;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 50%; vertical-align: bottom; border-bottom: #000000 2px solid;">
            <div style="text-align: center; color: #000000; font-size: 8pt; font-weight: bold;">Title</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 2%; vertical-align: bottom;">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt; font-weight: bold;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 18%; vertical-align: bottom; border-bottom: #000000 2px solid;">
            <div style="text-align: center; color: #000000; font-size: 8pt; font-weight: bold;">Date</div>
            <div style="color: #000000;">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 28%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 28%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 28%; vertical-align: top; border-bottom: #000000 2px solid;">/s/ William H. Lewis <br>
          </td>
          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 50%; vertical-align: top;">
            <div>President and Chief Executive Officer; Chairman of the Board of Directors</div>
          </td>
          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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            <div style="text-align: center;">&#160;May 19, 2023<font style="color: #000000;">&#160;</font></div>
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            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 18%; vertical-align: top;">
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          <td style="width: 28%; vertical-align: top;"> <br>
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          <td style="width: 50%; vertical-align: top;"> <br>
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          <td style="width: 2%; vertical-align: top;">
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          <td style="width: 18%; vertical-align: top;">
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          <td style="width: 28%; vertical-align: top; border-bottom: #000000 2px solid;">/s/ Sara Bonstein <br>
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            <div style="color: #000000;">&#160;</div>
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            <div style="color: #000000;">&#160;</div>
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          <td style="width: 18%; vertical-align: top;">
            <div style="text-align: center;">May 19, 2023</div>
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          <td style="width: 28%; vertical-align: top;">
            <div>Sara Bonstein</div>
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            <div style="color: #000000;">&#160;</div>
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          <td style="width: 18%; vertical-align: top;">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
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          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
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          <td style="width: 50%; vertical-align: top;">
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          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
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          <td style="width: 18%; vertical-align: top;">
            <div style="text-align: center;">May 19, 2023</div>
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        <tr>
          <td style="width: 28%; vertical-align: top;">
            <div>Alfred F. Altomari</div>
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            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
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          <td style="width: 50%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 18%; vertical-align: top;">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
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          <td style="width: 28%; vertical-align: top;">
            <div>&#160;</div>
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          <td style="width: 2%; vertical-align: top;">
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          <td style="width: 50%; vertical-align: top;">
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            <div style="color: #000000;">&#160;</div>
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          <td style="width: 2%; vertical-align: top;">
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            <div style="color: #000000;">&#160;</div>
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          <td style="width: 18%; vertical-align: top;">
            <div style="text-align: center;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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        <tr>
          <td style="width: 28%; vertical-align: top; border-bottom: #000000 2px solid;">
            <div style="text-align: center; color: #000000; font-variant: small-caps;">*</div>
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          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 50%; vertical-align: top;">
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          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 18%; vertical-align: top;">
            <div style="text-align: center;">May 19, 2023</div>
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          <td style="width: 28%; vertical-align: top;">
            <div>Elizabeth McKee Anderson</div>
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          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 50%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 18%; vertical-align: top;">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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        <tr>
          <td style="width: 28%; vertical-align: top;">
            <div>&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 2%; vertical-align: top;">
            <div>&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 50%; vertical-align: top;">
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            <div style="color: #000000;">&#160;</div>
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          <td style="width: 2%; vertical-align: top;">
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            <div style="color: #000000;">&#160;</div>
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          <td style="width: 18%; vertical-align: top;">
            <div style="text-align: center;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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        <tr>
          <td style="width: 28%; vertical-align: top; border-bottom: #000000 2px solid;">
            <div style="text-align: center; color: #000000; font-variant: small-caps;">*</div>
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          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 50%; vertical-align: top;">
            <div>Director<font style="color: #000000;">&#160;</font></div>
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          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 18%; vertical-align: top;">
            <div style="text-align: center;">May 19, 2023</div>
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        </tr>
        <tr>
          <td style="width: 28%; vertical-align: top;">
            <div>David R. Brennan</div>
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          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 50%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 18%; vertical-align: top;">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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        <tr>
          <td style="width: 28%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">&#160;</td>
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          <td rowspan="1" style="width: 28%; vertical-align: top;">&#160;</td>
          <td rowspan="1" style="width: 2%; vertical-align: top;">&#160;</td>
          <td rowspan="1" style="width: 50%; vertical-align: top;">&#160;</td>
          <td rowspan="1" style="width: 2%; vertical-align: top;">&#160;</td>
          <td rowspan="1" style="width: 18%; vertical-align: top;">&#160;</td>
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        <tr>
          <td style="width: 28%; vertical-align: top; border-bottom: #000000 2px solid;">
            <div style="text-align: center; color: #000000; font-variant: small-caps;">*</div>
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          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 50%; vertical-align: top;">
            <div>Director<font style="color: #000000;">&#160;</font></div>
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          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 18%; vertical-align: top;">
            <div style="text-align: center;">May 19, 2023</div>
          </td>
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          <td style="width: 28%; vertical-align: top;">
            <div>Clarissa Desjardins, Ph.D.</div>
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          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 50%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 18%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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        <tr>
          <td style="width: 28%; vertical-align: top;">
            <div>&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 2%; vertical-align: top;">
            <div>&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 50%; vertical-align: top;">
            <div>&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 2%; vertical-align: top;">
            <div>&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 18%; vertical-align: top;">
            <div style="text-align: center;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
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        <tr>
          <td style="width: 28%; vertical-align: top; border-bottom: #000000 2px solid;">
            <div style="text-align: center; color: #000000; font-variant: small-caps;">*</div>
          </td>
          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 50%; vertical-align: top;">
            <div>Director<font style="color: #000000;">&#160;</font></div>
          </td>
          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 18%; vertical-align: top;">
            <div style="text-align: center;">May 19, 2023</div>
          </td>
        </tr>
        <tr>
          <td style="width: 28%; vertical-align: top;">
            <div>Leo Lee</div>
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          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 50%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 18%; vertical-align: top;">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
        </tr>
        <tr>
          <td rowspan="1" style="width: 28%; vertical-align: top;">&#160;</td>
          <td rowspan="1" style="width: 2%; vertical-align: top;">&#160;</td>
          <td rowspan="1" style="width: 50%; vertical-align: top;">&#160;</td>
          <td rowspan="1" style="width: 2%; vertical-align: top;">&#160;</td>
          <td rowspan="1" style="width: 18%; vertical-align: top;">&#160;</td>
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        <tr>
          <td rowspan="1" style="width: 28%; vertical-align: top;">&#160;</td>
          <td rowspan="1" style="width: 2%; vertical-align: top;">&#160;</td>
          <td rowspan="1" style="width: 50%; vertical-align: top;">&#160;</td>
          <td rowspan="1" style="width: 2%; vertical-align: top;">&#160;</td>
          <td rowspan="1" style="width: 18%; vertical-align: top;">&#160;</td>
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        <tr>
          <td style="width: 28%; vertical-align: top; border-bottom: #000000 2px solid;">
            <div style="text-align: center; color: #000000; font-variant: small-caps;">*</div>
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          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 50%; vertical-align: top;">
            <div>Director<font style="color: #000000;">&#160;</font></div>
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          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 18%; vertical-align: top;">
            <div style="text-align: center;">May 19, 2023</div>
          </td>
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        <tr>
          <td style="width: 28%; vertical-align: top;">
            <div>David W.J. McGirr</div>
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          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 50%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
          </td>
          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 18%; vertical-align: top;">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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        <tr>
          <td style="width: 28%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 18%; vertical-align: top;">&#160;</td>
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          <td rowspan="1" style="width: 28%; vertical-align: top;">&#160;</td>
          <td rowspan="1" style="width: 2%; vertical-align: top;">&#160;</td>
          <td rowspan="1" style="width: 50%; vertical-align: top;">&#160;</td>
          <td rowspan="1" style="width: 2%; vertical-align: top;">&#160;</td>
          <td rowspan="1" style="width: 18%; vertical-align: top;">&#160;</td>
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          <td style="width: 28%; vertical-align: top; border-bottom: #000000 2px solid;">
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          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 50%; vertical-align: top;">
            <div>Director<font style="color: #000000;">&#160;</font></div>
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          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 18%; vertical-align: top;">
            <div style="text-align: center;">&#160;May 19, 2023</div>
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        <tr>
          <td style="width: 28%; vertical-align: top;">
            <div>Carol A. Schafer</div>
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          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 50%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 18%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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        <tr>
          <td style="width: 28%; vertical-align: top;">
            <div>&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 2%; vertical-align: top;">
            <div>&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 50%; vertical-align: top;">
            <div>&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 2%; vertical-align: top;">
            <div>&#160;</div>
            <div style="color: #000000;">&#160;</div>
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          <td style="width: 18%; vertical-align: top;">
            <div style="text-align: center;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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        <tr>
          <td style="width: 28%; vertical-align: top; border-bottom: #000000 2px solid;">
            <div style="text-align: center; color: #000000; font-variant: small-caps;">*</div>
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          <td style="width: 2%; vertical-align: top;">
            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
            <div style="color: #000000;">&#160;</div>
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            <div style="text-align: center;">&#160;May 19, 2023</div>
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        <tr>
          <td style="width: 28%; vertical-align: top;">
            <div>Melvin Sharoky, M.D.</div>
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            <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 1pt;">&#160;</div>
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          <td style="width: 50%; vertical-align: top;">
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          <td style="width: 2%; vertical-align: top;">
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          <td style="width: 18%; vertical-align: top;">
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            <div><font style="color: #000000;"><br>
              </font>&#160;</div>
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          <td style="width: 28%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 2%; vertical-align: top;">&#160;</td>
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    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" border="0" cellpadding="0" cellspacing="0">

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          <td rowspan="1" style="width: 4%; vertical-align: top; padding-bottom: 2px;"><font style="color: #000000;">* By:</font></td>
          <td rowspan="1" style="width: 24%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">/s/ Michael A. Smith<br>
          </td>
          <td rowspan="1" style="width: 2%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
          <td rowspan="1" style="width: 50%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
          <td rowspan="1" style="width: 2%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
          <td rowspan="1" style="width: 18%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
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        <tr>
          <td rowspan="1" style="width: 4%; vertical-align: top;">&#160;</td>
          <td rowspan="1" style="width: 24%; vertical-align: top;">Michael A. Smith <br>
          </td>
          <td rowspan="1" style="width: 2%; vertical-align: top;">&#160;</td>
          <td rowspan="1" style="width: 50%; vertical-align: top;">&#160;</td>
          <td rowspan="1" style="width: 2%; vertical-align: top;">&#160;</td>
          <td rowspan="1" style="width: 18%; vertical-align: top;">&#160;</td>
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        <tr>
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          <td rowspan="1" style="width: 24%; vertical-align: top;"><font style="font-style: italic;">Attorney-in-Fact</font></td>
          <td rowspan="1" style="width: 2%; vertical-align: top;">&#160;</td>
          <td rowspan="1" style="width: 50%; vertical-align: top;">&#160;</td>
          <td rowspan="1" style="width: 2%; vertical-align: top;">&#160;</td>
          <td rowspan="1" style="width: 18%; vertical-align: top;">&#160;</td>
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    <div style="color: #000000;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <br>
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<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>ny20009120x2_ex5-1.htm
<DESCRIPTION>EXHIBIT 5.1
<TEXT>
<html>
  <head>
    <title></title>
    <!-- Licensed to: Broadridge Financial Soultions, Inc.
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<body style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; text-align: left; color: #000000;" bgcolor="#ffffff">
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    <div style="text-align: right;"><font style="font-weight: bold;"> </font>
      <hr style="height: 4px; color: #000000; background-color: #000000; text-align: center; margin-left: auto; margin-right: auto; border: none;" align="center" noshade="noshade"><font style="font-weight: bold;">Exhibit 5.1</font><br>
    </div>
    <div> <br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="zb07430f582634142bf97ab7c47b6d7b6" border="0" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 80%; vertical-align: top;"><img src="ny20009120x2_ex5-1image01.jpg"></td>
          <td style="width: 20%; vertical-align: top;">
            <div style="font-size: 8pt;">HUNTON ANDREWS KURTH LLP</div>
            <div style="font-size: 8pt;">FILE NO: 058036.0000021</div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <div>May 19, 2023</div>
    <div><br>
    </div>
    <div>Insmed Incorporated</div>
    <div>700 US Highway 202/206</div>
    <div>Bridgewater, New Jersey 08807</div>
    <div><br>
    </div>
    <div style="text-align: center; font-weight: bold;">Insmed Incorporated</div>
    <div style="text-align: center; font-weight: bold;">Registration Statement on Form S-8</div>
    <div><br>
    </div>
    <div>Ladies and Gentlemen:</div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">We have acted as Virginia counsel to Insmed Incorporated, a Virginia corporation (the &#8220;Company&#8221;), in connection with the preparation and filing by the Company of a Registration Statement on Form S-8 (the &#8220;Registration
      Statement&#8221;) with the Securities and Exchange Commission (the &#8220;Commission&#8221;) on the date hereof pursuant to the Securities Act of 1933, as amended (the &#8220;Securities Act&#8221;).&#160; The Registration Statement relates to the registration of (i) 10,500,000 shares
      of the Company&#8217;s common stock, par value $0.01 per share (&#8220;Common Stock&#8221;), issuable under the Company&#8217;s Amended and Restated 2019 Incentive Plan (as amended, the &#8220;Plan&#8221;) and (ii) an aggregate of 1,600,150 shares of Common Stock (together with the
      shares in (i), the &#8220;Shares&#8221;) issuable upon the exercise of options to purchase shares of Common Stock granted pursuant to the Non-Qualified Stock Option Inducement Award Agreements referenced in the Registration Statement (the &#8220;Inducement Award
      Agreements&#8221;), in each case, substantially in the form filed as an exhibit to the Registration Statement.</div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">This opinion letter is being furnished in accordance with the requirements of Item 8(a) of Form S-8 and Item 601(b)(5)(i) of Regulation S-K.</div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">In connection with this opinion letter, we have examined originals or copies, certified or otherwise identified to our satisfaction, of such documents and records of the Company, certificates of public officials and
      officers of the Company and such other documents, certificates and records as we have deemed necessary to render the opinions set forth herein, including, among other things, (i) the Company&#8217;s Articles of Incorporation, as amended through the date
      hereof, (ii) the Company&#8217;s Amended and Restated Bylaws, as amended through the date hereof, (iii) the Plan, (iv) a form of the Inducement Award Agreement, (v) the Registration Statement, (vi) resolutions of the Company&#8217;s Board of Directors, (vii)
      resolutions of the Compensation Committee of the Company&#8217;s Board of Directors and (viii) a certificate issued by the Clerk of the State Corporation Commission of the Commonwealth of Virginia on the date hereof to the effect that the Company is
      existing under the laws of the Commonwealth of Virginia and in good standing (the &#8220;Good Standing Certificate&#8221;).</div>
    <div><br>
    </div>
    <div style="text-align: center; font-size: 8pt;">ATLANTA&#160;&#160; AUSTIN&#160;&#160; BANGKOK&#160;&#160; BEIJING&#160;&#160; BOSTON&#160;&#160; BRUSSELS&#160;&#160; CHARLOTTE&#160;&#160; DALLAS&#160;&#160; DUBAI&#160;&#160; HOUSTON</div>
    <div style="text-align: center; font-size: 8pt;">LONDON&#160;&#160; LOS ANGELES&#160;&#160; MIAMI&#160;&#160; NEW YORK&#160;&#160; RICHMOND&#160;&#160; SAN FRANCISCO&#160;&#160; TOKYO&#160;&#160; TYSONS&#160;&#160; WASHINGTON, DC</div>
    <div style="text-align: center; font-size: 8pt;">www.HuntonAK.com</div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
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        <hr style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;" noshade="noshade"></div>
    </div>
    <div><img src="ny20009120x2_ex5-1image01.jpg"></div>
    <div><br>
    </div>
    <div>
      <div>Insmed Incorporated</div>
      <div>May 19, 2023</div>
      <div>Page 2</div>
    </div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">For purposes of the opinions expressed below, we have assumed (i) the legal capacity of all natural persons, (ii) the genuineness of all signatures, (iii) the authenticity of all documents submitted to us as originals,
      (iv) the conformity to authentic original documents of all documents submitted to us as certified, electronic or photostatic copies and (v) the due authorization, execution and delivery of all documents by all parties and the validity, binding effect
      and enforceability thereof on such parties (other than the authorization, execution and delivery of certain documents by the Company).</div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">As to factual matters, we have relied upon, and assumed the accuracy of, representations included in the documents submitted to us, upon certificates of officers of the Company and upon certificates of public officials.&#160;
      Except as otherwise expressly indicated, we have not undertaken any independent investigation of factual matters.</div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">We do not purport to express an opinion on any laws other than those of the Commonwealth of Virginia.</div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">Based upon the foregoing and such other information and documents as we have considered necessary for the purposes hereof, and subject to the assumptions, qualifications and limitations stated herein, we are of the
      opinion that:</div>
    <div><br>
    </div>
    <div style="text-indent: 36pt; margin-left: 36pt;">1.&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;The Company is a corporation validly existing and in good standing under the laws of the Commonwealth of Virginia.</div>
    <div><br>
    </div>
    <div style="text-indent: 36pt; margin-left: 36pt;">2.&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;The Shares have been duly authorized and, when and to the extent issued in accordance with the terms of, as applicable, (a) the Plan and any award agreement entered into under the Plan or
      (b) the Inducement Award Agreements, the Shares will be validly issued, fully paid and nonassessable.</div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">The opinion set forth in paragraph 1 above as to the valid existence and good standing of the Company is based solely upon our review of the Good Standing Certificate.</div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">We hereby consent to the filing of this opinion letter with the Commission as an exhibit to the Registration Statement.&#160; In giving this consent, we do not admit that we are within the category of persons whose consent is
      required by Section 7 of the Securities Act and the rules and regulations of the Commission promulgated thereunder.</div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">This opinion letter is rendered as of the date hereof, and we disclaim any obligation to advise you of facts, circumstances, events or developments that hereafter may be brought to our attention and that may alter,
      affect or modify the opinion expressed herein.&#160; This opinion letter is expressly limited to the matters set forth above and we render no opinion, whether by implication or otherwise, as to any matters beyond the matters expressly set forth herein.</div>
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          <tr>
            <td style="width: 50.00%;">
              <div>&#160;</div>
            </td>
            <td style="width: 50.00%;">Very truly yours,</td>
          </tr>
          <tr>
            <td style="width: 50.00%;">
              <div>&#160;</div>
            </td>
            <td style="width: 50.00%;">
              <div>&#160;</div>
            </td>
          </tr>
          <tr>
            <td style="width: 50.00%;">
              <div>&#160;</div>
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            <td style="width: 50.00%;">
              <div>/s/ Hunton Andrews Kurth LLP</div>
            </td>
          </tr>

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    </div>
    <div><br>
    </div>
    <div>
      <hr style="height: 2px; color: #000000; background-color: #000000; text-align: center; margin-left: auto; margin-right: auto; border: none;" align="center" noshade="noshade"></div>
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</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.2
<SEQUENCE>3
<FILENAME>ny20009120x2_ex23-2.htm
<DESCRIPTION>EXHIBIT 23.2
<TEXT>
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  <head>
    <title></title>
    <!-- Licensed to: Broadridge Financial Soultions, Inc.
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<body style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; text-align: left; color: #000000;" bgcolor="#ffffff">
  <div>
    <hr style="height: 4px; color: #000000; background-color: #000000; text-align: center; margin-left: auto; margin-right: auto; border: none;" align="center" noshade="noshade">
    <div> <br>
    </div>
    <div>
      <div style="text-align: right; color: #000000; font-weight: bold;">Exhibit 23.2</div>
      <div><br>
      </div>
      <div style="text-align: center; color: #000000;">Consent of Independent Registered Public Accounting Firm</div>
      <div><br>
      </div>
      <div style="text-align: justify; color: #000000;">We consent to the incorporation by reference in the Registration Statement (Form S-8) pertaining to the Insmed Incorporated Amended and
        Restated 2019 Incentive Plan and Insmed Incorporated Non-Qualified Stock Option Inducement Awards of Insmed Incorporated of our reports dated February 23, 2023, with respect to the consolidated financial statements of Insmed Incorporated and the
        effectiveness of internal control over financial reporting of Insmed Incorporated included in its Annual Report (Form 10-K) for the year ended December 31, 2022, filed with the Securities and Exchange Commission.</div>
      <div><br>
      </div>
      <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z9c1fd116e4fe482484b5bdf2f33f8d06" cellpadding="0" cellspacing="0">

          <tr>
            <td style="width: 50%; vertical-align: top;">
              <div>&#160;</div>
              <div>&#160;</div>
              <div>/s/ Ernst &amp; Young LLP</div>
            </td>
            <td style="width: 50%; vertical-align: top;">&#160;</td>
          </tr>
          <tr>
            <td style="width: 50%; vertical-align: top;">
              <div>Iselin, New Jersey</div>
            </td>
            <td style="width: 50%; vertical-align: top;">&#160;</td>
          </tr>
          <tr>
            <td style="width: 50%; vertical-align: top;">
              <div>May 19, 2023</div>
            </td>
            <td style="width: 50%; vertical-align: middle;">&#160;</td>
          </tr>

      </table>
      <div><br>
      </div>
      <div><br>
      </div>
      <div>
        <hr style="height: 2px; color: #000000; background-color: #000000; text-align: center; margin-left: auto; margin-right: auto; border: none;" align="center" noshade="noshade"></div>
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  </div>
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</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>4
<FILENAME>ny20009120x2_ex107.htm
<DESCRIPTION>FILING FEES TABLE
<TEXT>
<html>
  <head>
    <title></title>
    <!-- Licensed to: Broadridge Financial Soultions, Inc.
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<body style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; text-align: left; color: #000000;" bgcolor="#ffffff">
  <div>
    <div style="text-align: right; font-family: 'Times New Roman',Times,serif; font-weight: bold;">
      <hr style="height: 4px; color: #000000; background-color: #000000; text-align: center; margin-left: auto; margin-right: auto; border: none;" align="center" noshade="noshade">Exhibit 107</div>
    <div><br>
    </div>
    <div style="text-align: center; font-weight: bold;">CALCULATION OF FILING FEE TABLE</div>
    <div>&#160;</div>
    <div style="text-align: center; font-weight: bold;">Form S-8</div>
    <div style="text-align: center;">(Form Type)</div>
    <div>&#160;</div>
    <div style="text-align: center; font-weight: bold;">Insmed Incorporated</div>
    <div style="text-align: center;">(Exact Name of Registrant as Specified in its Charter)</div>
    <div>&#160;</div>
    <div style="text-align: center; font-weight: bold;">Table 1 - Newly Registered Securities</div>
    <div><br>
    </div>
    <table style="font-family: 'Times New Roman',Times,serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: rgb(0, 0, 0);" id="z2daf3eaa5dde490ebe847ace8819be4e" border="0" cellpadding="0" cellspacing="0">

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          <td style="width: 7%; vertical-align: bottom; border-left: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">Security Type</div>
          </td>
          <td style="width: 15%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">Security Class</div>
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">Title</div>
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          <td style="width: 6.94%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">Fee Calculation<br>
              Rule</div>
          </td>
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            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">Amount</div>
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">Registered(1)</div>
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          <td style="width: 11.22%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">Proposed</div>
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">Maximum</div>
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">Offering<br>
              Price</div>
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">Per Share</div>
          </td>
          <td style="width: 18%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div>&#160;</div>
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">Maximum</div>
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">Aggregate</div>
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">Offering</div>
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">Price</div>
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            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">Fee Rate</div>
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            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">Amount of</div>
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">Registration</div>
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 8pt;">Fee</div>
          </td>
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          <td style="width: 7%; vertical-align: middle; border-left: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 15%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 6.94%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 14.79%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 11.22%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 18%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 14.46%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 12.58%; vertical-align: middle; border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
        </tr>
        <tr>
          <td style="width: 7%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Equity</div>
          </td>
          <td style="width: 15%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Common Stock, par value $0.01 per share, to be issued under the Insmed Incorporated Amended and Restated 2019 Incentive Plan</div>
          </td>
          <td style="width: 6.94%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Rules 457(c) and 457(h)</div>
          </td>
          <td style="width: 14.79%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">10,500,000(2)</div>
          </td>
          <td style="width: 11.22%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$18.36(3)</div>
          </td>
          <td style="width: 18%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$192,780,000.00(3)</div>
          </td>
          <td style="width: 14.46%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">0.0001102</div>
          </td>
          <td style="width: 12.58%; vertical-align: bottom; border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$21,244.36</div>
          </td>
        </tr>
        <tr>
          <td style="width: 7%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Equity</div>
          </td>
          <td style="width: 15%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Common Stock, par value $0.01 per share</div>
          </td>
          <td style="width: 6.94%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Rule 457(h)</div>
          </td>
          <td style="width: 14.79%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">158,530(4)</div>
          </td>
          <td style="width: 11.22%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; font-family: 'Times New Roman', Times, serif;"><font style="color: #000000;">$</font><font style="font-size: 12pt;">&#160;</font><font style="color: #000000;">17.93(5)</font></div>
          </td>
          <td style="width: 18%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; font-family: 'Times New Roman', Times, serif;"><font style="color: #000000;">$</font><font style="font-size: 12pt;">&#160;</font><font style="color: #000000;">2,842,442.90(5)</font></div>
          </td>
          <td style="width: 14.46%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">0.0001102</div>
          </td>
          <td style="width: 12.58%; vertical-align: bottom; border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$313.24</div>
          </td>
        </tr>
        <tr>
          <td style="width: 7%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Equity</div>
          </td>
          <td style="width: 15%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Common Stock, par value $0.01 per share</div>
          </td>
          <td style="width: 6.94%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Rule 457(h)</div>
          </td>
          <td style="width: 14.79%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">146,070(6)</div>
          </td>
          <td style="width: 11.22%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$20.89(5)</div>
          </td>
          <td style="width: 18%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$3,051,402.30(5)</div>
          </td>
          <td style="width: 14.46%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">0.0001102</div>
          </td>
          <td style="width: 12.58%; vertical-align: bottom; border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$336.27</div>
          </td>
        </tr>
        <tr>
          <td style="width: 7%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Equity</div>
          </td>
          <td style="width: 15%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Common Stock, par value $0.01 per share</div>
          </td>
          <td style="width: 6.94%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Rule 457(h)</div>
          </td>
          <td style="width: 14.79%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">53,570(7)</div>
          </td>
          <td style="width: 11.22%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$20.88(5)</div>
          </td>
          <td style="width: 18%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$1,118,541.60(5)</div>
          </td>
          <td style="width: 14.46%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">0.0001102</div>
          </td>
          <td style="width: 12.58%; vertical-align: bottom; border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$123.27</div>
          </td>
        </tr>
        <tr>
          <td style="width: 7%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Equity</div>
          </td>
          <td style="width: 15%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Common Stock, par value $0.01 per share</div>
          </td>
          <td style="width: 6.94%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Rule 457(h)</div>
          </td>
          <td style="width: 14.79%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">35,910(8)</div>
          </td>
          <td style="width: 11.22%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$25.19(5)</div>
          </td>
          <td style="width: 18%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$904,572.90(5)</div>
          </td>
          <td style="width: 14.46%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">0.0001102</div>
          </td>
          <td style="width: 12.58%; vertical-align: bottom; border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$99.69</div>
          </td>
        </tr>
        <tr>
          <td style="width: 7%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Equity</div>
          </td>
          <td style="width: 15%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Common Stock, par value $0.01 per share</div>
          </td>
          <td style="width: 6.94%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Rule 457(h)</div>
          </td>
          <td style="width: 14.79%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">144,180(9)</div>
          </td>
          <td style="width: 11.22%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$22.16(5)</div>
          </td>
          <td style="width: 18%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$3,195,028.80(5)</div>
          </td>
          <td style="width: 14.46%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">0.0001102</div>
          </td>
          <td style="width: 12.58%; vertical-align: bottom; border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$352.10</div>
          </td>
        </tr>
        <tr>
          <td style="width: 7%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Equity</div>
          </td>
          <td style="width: 15%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Common Stock, par value $0.01 per share</div>
          </td>
          <td style="width: 6.94%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Rule 457(h)</div>
          </td>
          <td style="width: 14.79%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">127,060(10)</div>
          </td>
          <td style="width: 11.22%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$17.50(5)</div>
          </td>
          <td style="width: 18%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$2,223,550.00(5)</div>
          </td>
          <td style="width: 14.46%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">0.0001102</div>
          </td>
          <td style="width: 12.58%; vertical-align: bottom; border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$245.04</div>
          </td>
        </tr>
        <tr>
          <td style="width: 7%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Equity</div>
          </td>
          <td style="width: 15%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Common Stock, par value $0.01 per share</div>
          </td>
          <td style="width: 6.94%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Rule 457(h)</div>
          </td>
          <td style="width: 14.79%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">89,730(11)</div>
          </td>
          <td style="width: 11.22%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$19.12(5)</div>
          </td>
          <td style="width: 18%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$1,715,637.60(5)</div>
          </td>
          <td style="width: 14.46%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">0.0001102</div>
          </td>
          <td style="width: 12.58%; vertical-align: bottom; border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$189.07</div>
          </td>
        </tr>
        <tr>
          <td style="width: 7%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Equity</div>
          </td>
          <td style="width: 15%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Common Stock, par value $0.01 per share</div>
          </td>
          <td style="width: 6.94%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Rule 457(h)</div>
          </td>
          <td style="width: 14.79%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">107,580(12)</div>
          </td>
          <td style="width: 11.22%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$19.18(5)</div>
          </td>
          <td style="width: 18%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$2,063,384.40(5)</div>
          </td>
          <td style="width: 14.46%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">0.0001102</div>
          </td>
          <td style="width: 12.58%; vertical-align: bottom; border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$227.39</div>
          </td>
        </tr>
        <tr>
          <td style="width: 7%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Equity</div>
          </td>
          <td style="width: 15%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Common Stock, par value $0.01 per share</div>
          </td>
          <td style="width: 6.94%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Rule 457(h)</div>
          </td>
          <td style="width: 14.79%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">240,010(13)</div>
          </td>
          <td style="width: 11.22%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$21.62(5)</div>
          </td>
          <td style="width: 18%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$5,189,016.20(5)</div>
          </td>
          <td style="width: 14.46%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">0.0001102</div>
          </td>
          <td style="width: 12.58%; vertical-align: bottom; border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$571.83</div>
          </td>
        </tr>
        <tr>
          <td style="width: 7%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Equity</div>
          </td>
          <td style="width: 15%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Common Stock, par value $0.01 per share</div>
          </td>
          <td style="width: 6.94%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Rule 457(h)</div>
          </td>
          <td style="width: 14.79%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">136,800(14)</div>
          </td>
          <td style="width: 11.22%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$20.24(5)</div>
          </td>
          <td style="width: 18%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$2,768,832.00(5)</div>
          </td>
          <td style="width: 14.46%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">0.0001102</div>
          </td>
          <td style="width: 12.58%; vertical-align: bottom; border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$305.13</div>
          </td>
        </tr>
        <tr>
          <td style="width: 7%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Equity</div>
          </td>
          <td style="width: 15%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Common Stock, par value $0.01 per share</div>
          </td>
          <td style="width: 6.94%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Rule 457(h)</div>
          </td>
          <td style="width: 14.79%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">182,880(15)</div>
          </td>
          <td style="width: 11.22%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$17.37(5)</div>
          </td>
          <td style="width: 18%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$3,176,625.60(5)</div>
          </td>
          <td style="width: 14.46%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">0.0001102</div>
          </td>
          <td style="width: 12.58%; vertical-align: bottom; border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$350.07</div>
          </td>
        </tr>
        <tr>
          <td style="width: 7%; vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Equity</div>
          </td>
          <td style="width: 15%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Common Stock, par value $0.01 per share</div>
          </td>
          <td style="width: 6.94%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Rule 457(h)</div>
          </td>
          <td style="width: 14.79%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">177,830(16)</div>
          </td>
          <td style="width: 11.22%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$20.17(5)</div>
          </td>
          <td style="width: 18%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$3,586,831.10(5)</div>
          </td>
          <td style="width: 14.46%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">0.0001102</div>
          </td>
          <td style="width: 12.58%; vertical-align: bottom; border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$395.27</div>
          </td>
        </tr>
        <tr>
          <td style="width: 7%; vertical-align: middle; border-left: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 15%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 6.94%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 14.79%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 11.22%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 18%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 14.46%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 12.58%; vertical-align: middle; border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
        </tr>
        <tr>
          <td colspan="4" style="vertical-align: middle; border-left: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 11.22%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 18%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 14.46%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 12.58%; vertical-align: middle; border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
        </tr>
        <tr>
          <td colspan="4" style="vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Total Offering Amounts</div>
          </td>
          <td style="width: 11.22%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 18%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$224,615,865.40</div>
          </td>
          <td style="width: 14.46%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 12.58%; vertical-align: bottom; border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$24,752.73</div>
          </td>
        </tr>
        <tr>
          <td colspan="4" style="vertical-align: middle; border-left: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 11.22%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 18%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 14.46%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 12.58%; vertical-align: middle; border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
        </tr>
        <tr>
          <td colspan="4" style="vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Total Fee Offsets(17)</div>
          </td>
          <td style="width: 11.22%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 18%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 14.46%; vertical-align: bottom; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 12.58%; vertical-align: bottom; border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$0</div>
          </td>
        </tr>
        <tr>
          <td colspan="4" style="vertical-align: middle; border-left: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 11.22%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 18%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 14.46%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 12.58%; vertical-align: middle; border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
        </tr>
        <tr>
          <td colspan="4" style="vertical-align: top; border-left: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">Net Fee Due</div>
          </td>
          <td style="width: 11.22%; vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 18%; vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 14.46%; vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0); border-left: 1px solid rgb(0, 0, 0);">&#160;</td>
          <td style="width: 12.58%; vertical-align: bottom; border-width: 1px; border-style: solid; border-color: rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif;">$24,752.73</div>
          </td>
        </tr>

    </table>
    <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
      <div class="BRPFPageBreak" style="page-break-after: always;">
        <hr style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;" noshade="noshade"></div>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z6851cb03b2cd41d886fa387ffdfbedf6" border="0" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 3%; vertical-align: top;">
            <div style="color: #000000;">(1)</div>
          </td>
          <td style="width: 97%; vertical-align: top;">
            <div style="color: #000000;">Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the &#8220;Securities Act&#8221;), this Registration Statement on Form S-8 (the &#8220;Registration Statement&#8221;) also covers such indeterminable number of
              additional shares of Insmed Incorporated&#8217;s (the &#8220;Registrant&#8221;) common stock, par value $0.01 per share (&#8220;Common Stock&#8221;), as may become issuable under the Registrant&#8217;s Amended and Restated 2019 Incentive Plan (the &#8220;Incentive Plan&#8221;), or any of
              the Registrant&#8217;s Non-Qualified Stock Option Inducement Awards (as defined below) to prevent dilution in the event of a reorganization, reclassification, stock split, dividend or distribution, or any similar transaction.</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">&#160;</td>
          <td style="width: 97%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">
            <div style="color: #000000;">(2)</div>
          </td>
          <td style="width: 97%; vertical-align: top;">
            <div style="color: #000000;">Registers additional shares of Common Stock to be issued pursuant to future awards under the Incentive Plan.</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">&#160;</td>
          <td style="width: 97%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">
            <div style="color: #000000;">(3)</div>
          </td>
          <td style="width: 97%; vertical-align: top;">
            <div style="color: #000000;">Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(c) and Rule 457(h) under the Securities Act, based upon the average of the high and low prices of the Registrant&#8217;s Common
              Stock on the Nasdaq Global Select Market on May 17, 2023.</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">&#160;</td>
          <td style="width: 97%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">
            <div style="color: #000000;">(4)</div>
          </td>
          <td style="width: 97%; vertical-align: top;">
            <div>Pursuant to the Registrant&#8217;s non-qualified stock option inducement awards to 24 new employees on June 1, 2022.</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">&#160;</td>
          <td style="width: 97%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">
            <div style="color: #000000;">(5)</div>
          </td>
          <td style="width: 97%; vertical-align: top;">
            <div style="color: #000000;">Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(h) under the Securities Act, based upon the price at which the relevant stock options may be exercised.</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">&#160;</td>
          <td style="width: 97%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">
            <div style="color: #000000;">(6)</div>
          </td>
          <td style="width: 97%; vertical-align: top;">
            <div>Pursuant to the Registrant&#8217;s non-qualified stock option inducement awards to 18 new employees on July 1, 2022.</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">&#160;</td>
          <td style="width: 97%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">
            <div style="color: #000000;">(7)</div>
          </td>
          <td style="width: 97%; vertical-align: top;">
            <div style="color: #000000;">Pursuant to the Registrant&#8217;s non-qualified stock option inducement awards to 11 new employees on August 1, 2022.</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">&#160;</td>
          <td style="width: 97%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">
            <div style="color: #000000;">(8)</div>
          </td>
          <td style="width: 97%; vertical-align: top;">
            <div style="color: #000000;">Pursuant to the Registrant&#8217;s non-qualified stock option inducement awards to 10 new employees on September 1, 2022.</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">&#160;</td>
          <td style="width: 97%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">
            <div style="color: #000000;">(9)</div>
          </td>
          <td style="width: 97%; vertical-align: top;">
            <div style="color: #000000;">Pursuant to the Registrant&#8217;s non-qualified stock option inducement awards to 18 new employees on October 3, 2022.</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">&#160;</td>
          <td style="width: 97%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">
            <div style="color: #000000;">(10)</div>
          </td>
          <td style="width: 97%; vertical-align: top;">
            <div style="color: #000000;">Pursuant to the Registrant&#8217;s non-qualified stock option inducement awards to 18 new employees on November 1, 2022.</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">&#160;</td>
          <td style="width: 97%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">
            <div style="color: #000000;">(11)</div>
          </td>
          <td style="width: 97%; vertical-align: top;">
            <div style="color: #000000;">Pursuant to the Registrant&#8217;s non-qualified stock option inducement awards to 15 new employees on December 1, 2022.</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">&#160;</td>
          <td style="width: 97%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">
            <div style="color: #000000;">(12)</div>
          </td>
          <td style="width: 97%; vertical-align: top;">
            <div style="color: #000000;">Pursuant to the Registrant&#8217;s non-qualified stock option inducement awards to 10 new employees on January 3, 2023.</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">&#160;</td>
          <td style="width: 97%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">
            <div style="color: #000000;">(13)</div>
          </td>
          <td style="width: 97%; vertical-align: top;">
            <div style="color: #000000;">Pursuant to the Registrant&#8217;s non-qualified stock option inducement awards to 18 new employees on February 1, 2023.</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">&#160;</td>
          <td style="width: 97%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">
            <div style="color: #000000;">(14)</div>
          </td>
          <td style="width: 97%; vertical-align: top;">
            <div style="color: #000000;">Pursuant to the Registrant&#8217;s non-qualified stock option inducement awards to 17 new employees on March 1, 2023.</div>
            <div>&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">
            <div style="color: #000000;">(15)</div>
          </td>
          <td style="width: 97%; vertical-align: top;">
            <div style="color: #000000;">Pursuant to the Registrant&#8217;s non-qualified stock option inducement awards to 24 new employees on April 3, 2023.</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">&#160;</td>
          <td style="width: 97%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">
            <div style="color: #000000;">(16)</div>
          </td>
          <td style="width: 97%; vertical-align: top;">
            <div style="color: #000000;">Pursuant to the Registrant&#8217;s non-qualified stock option inducement awards to 18 new employees on May 1, 2023 (together with the Registrant&#8217;s non-qualified stock option inducement awards described in footnotes (4),
              (6), (7), (8), (9), (10), (11), (12), (13), (14) and (15), the &#8220;Non-Qualified Stock Option Inducement Awards&#8221;).</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">&#160;</td>
          <td style="width: 97%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 3%; vertical-align: top;">
            <div style="color: #000000;">(17)</div>
          </td>
          <td style="width: 97%; vertical-align: top;">
            <div style="color: #000000;">The Registrant does not have any fee offsets.</div>
          </td>
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