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Summary of Significant Accounting Policies - Narrative (Details) $ in Thousands | 12 Months Ended |  |
--- | --- | --- | ---
Dec. 31, 2023 USD ($) segment reportingUnit | Dec. 31, 2022 USD ($) | Jan. 01, 2022 USD ($)
Fair Value Measurement Inputs and Valuation Techniques [Line Items] |  |  |
Number of reporting units | reportingUnit | 1 |  |
Number of operating segments | segment | 1 |  |
Number of reportable segments | segment | 1 |  |
Debt, long-term | $ 1,155,313 | $ 1,125,250 |
Deferred tax liabilities | (22,591) | (24,966) |
Accumulated deficit | (3,446,145) | (2,696,578) |
Additional paid-in capital | $ (3,113,487) | $ (2,782,416) |
Cumulative Effect, Period of Adoption, Adjustment |  |  |
Fair Value Measurement Inputs and Valuation Techniques [Line Items] |  |  |
Debt, long-term |  |  | $ 221,900
Unamortized debt issuance costs |  |  | 6,100
Deferred tax liabilities |  |  | 1,400
Accumulated deficit |  |  | 50,200
Additional paid-in capital |  |  | $ 264,600
Laboratory equipment, office equipment, manufacturing equipment and furniture and fixtures |  |  |
Fair Value Measurement Inputs and Valuation Techniques [Line Items] |  |  |
Estimated Useful Life (years) | 7 years |  |
Minimum | Computer hardware and software |  |  |
Fair Value Measurement Inputs and Valuation Techniques [Line Items] |  |  |
Estimated Useful Life (years) | 3 years |  |
Maximum | Computer hardware and software |  |  |
Fair Value Measurement Inputs and Valuation Techniques [Line Items] |  |  |
Estimated Useful Life (years) | 5 years |  |

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