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Income Taxes - Components of Deferred Tax Assets and Liabilities (Details) - USD ($) $ in Thousands | Dec. 31, 2023 | Dec. 31, 2022
--- | --- | ---
Deferred tax assets: |  |
Net operating loss carryforwards | $ 563,869 | $ 499,029
General business credits | 182,006 | 157,181
Product license | 3,867 | 4,317
Inventory | 2,341 | 1,470
Lease liabilities | 12,000 | 12,965
Stock-based compensation | 27,916 | 23,724
Capitalized R&D | 115,299 | 56,275
Other | 19,286 | 15,001
Deferred tax assets | 926,584 | 769,962
Valuation allowance | (904,078) | (745,135)
Deferred tax assets, net of valuation allowance | 22,506 | 24,827
Deferred tax liabilities: |  |
Intangibles | (13,006) | (13,739)
Right-of-use assets | (9,585) | (11,227)
Deferred tax liabilities | (22,591) | (24,966)
Net deferred tax liabilities | $ (85) | $ (139)

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