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Summary of Significant Accounting Policies (Tables)

12 Months Ended

Dec. 31, 2023

Accounting Policies [Abstract]

Schedule of Percentage of Total Gross Product Revenue Represented by the Three Largest Customers

The following table presents the percentage of gross product revenue represented by the Company's three largest customers as of the year ended December 31, 2023 and their respective percentages for the year ended December 31, 2022.

			December 31,
			2023						2022
Customer A			35%						34%
Customer B			34%						36%
Customer C			19%						20%

Schedule of Reconciliation of the Weighted Average Number of Shares Used to Compute Basic and Diluted Net Loss per Share

The following table sets forth the reconciliation of the weighted average number of shares used to compute basic and diluted net loss per share for the years ended December 31, 2023, 2022 and 2021.

			Years Ended December 31,
			2023						2022						2021
			(in thousands, except per share amounts)
Numerator:
Net loss			$	(749,567)					$	(481,534)					$	(434,654)
Denominator:
Weighted average common shares used in calculation of basic net loss per share:			140,433						123,035						112,111
Effect of dilutive securities:
Common stock options			—						—						—
RS and RSUs			—						—						—
PSUs			—						—						—
Convertible debt securities			—						—						—
Weighted average common shares outstanding used in calculation of diluted net loss per share			140,433						123,035						112,111
Net loss per share:
Basic and diluted			$	(5.34)					$	(3.91)					$	(3.88)

Schedule of Potentially Dilutive Securities Excluded from Computations of Diluted Weighted Average Common Shares Outstanding

The following potentially dilutive securities have been excluded from the computations of diluted weighted average common shares outstanding as of December 31, 2023, 2022 and 2021 as their effect would have been anti-dilutive (in thousands).

			As of December 31,
			2023						2022						2021
Common stock options			22,513						17,525						14,089
Unvested RS and RSUs			2,750						1,520						1,020
PSUs			666						671						—
Convertible debt securities			23,438						23,438						23,438

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Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities.

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