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Consolidated Statements of Shareholders' Equity - USD ($)
$ in Thousands
Total
Cumulative Effect, Period of Adoption, Adjustment
Common Stock
Additional Paid-in Capital
Additional Paid-in Capital
Cumulative Effect, Period of Adoption, Adjustment
Accumulated Deficit
Accumulated Deficit
Cumulative Effect, Period of Adoption, Adjustment
Accumulated Other Comprehensive Income (Loss)
Balance (in shares) at Dec. 31, 2020     102,763,000          
Balance at Dec. 31, 2020 $ 275,884   $ 1,028 $ 2,105,252   $ (1,830,589)   $ 193
Comprehensive loss:                
Net loss (434,654)         (434,654)    
Other comprehensive income (loss) $ 775             775
Exercise of stock options and ESPP shares issuance (in shares) 1,235,186   1,359,000          
Exercise of stock options and ESPP shares issuance $ 22,035   $ 13 22,022        
Net proceeds from issuance of common stock (in shares)     11,500,000          
Net proceeds from issuance of common stock 269,886   $ 115 269,771        
Equity component of convertible debt issuance 196,358     196,358        
Equity component of convertible debt redemption (37,846)     (37,846)        
Issuance of common stock for vesting of RSUs (in shares)     217,000          
Issuance of common stock for vesting of RSUs 2   $ 2          
Issuance of common stock for business acquisition (in shares)     2,899,000          
Issuance of common stock for business acquisition 72,007   $ 29 71,978        
Stock-based compensation expense 46,021     46,021        
Balance (in shares) at Dec. 31, 2021     118,738,000          
Balance at Dec. 31, 2021 $ 410,468 $ (214,410) $ 1,187 2,673,556 $ (264,609) (2,265,243) $ 50,199 968
Comprehensive loss:                
Change in Accounting Principle, Accounting Standards Update, Transition Option Elected [Extensible Enumeration] Accounting Standards Update 2020-06 [Member]              
Net loss $ (481,534)         (481,534)    
Other comprehensive income (loss) $ (212)             (212)
Exercise of stock options and ESPP shares issuance (in shares) 1,151,341   1,328,000          
Exercise of stock options and ESPP shares issuance $ 19,500   $ 14 19,486        
Net proceeds from issuance of common stock (in shares)     15,040,000          
Net proceeds from issuance of common stock 292,153   $ 150 292,003        
Issuance of common stock for vesting of RSUs (in shares)     377,000          
Issuance of common stock for vesting of RSUs 4   $ 4          
Deferred payment for Business Acquisition (in shares)     171,000          
Deferred payment for Business Acquisition 4,296   $ 2 4,294        
Stock-based compensation expense 57,686     57,686        
Balance (in shares) at Dec. 31, 2022     135,654,000          
Balance at Dec. 31, 2022 87,951   $ 1,357 2,782,416   (2,696,578)   756
Comprehensive loss:                
Net loss (749,567)         (749,567)    
Other comprehensive income (loss) $ (1,501)             (1,501)
Exercise of stock options and ESPP shares issuance (in shares) 871,933   1,142,000          
Exercise of stock options and ESPP shares issuance $ 18,399   $ 12 18,387        
Net proceeds from issuance of common stock (in shares)     6,531,000          
Net proceeds from issuance of common stock 152,475   $ 65 152,410        
Issuance of common stock for vesting of RSUs (in shares)     543,000          
Issuance of common stock for vesting of RSUs 5   $ 5          
Issuance of common stock for business acquisition (in shares)     3,931,000          
Issuance of common stock for business acquisition 81,640   $ 39 81,601        
Deferred payment for Business Acquisition (in shares)     177,000          
Deferred payment for Business Acquisition 3,897   $ 2 3,895        
Stock-based compensation expense 74,778     74,778        
Balance (in shares) at Dec. 31, 2023     147,978,000          
Balance at Dec. 31, 2023 $ (331,923)   $ 1,480 $ 3,113,487   $ (3,446,145)   $ (745)