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License and Other Agreements (Details)
€ in Millions, $ in Millions
1 Months Ended 3 Months Ended 12 Months Ended 240 Months Ended
Dec. 31, 2020
USD ($)
Apr. 30, 2020
Oct. 31, 2016
USD ($)
Jul. 31, 2014
Feb. 28, 2014
USD ($)
kg
Apr. 30, 2008
EUR (€)
Dec. 31, 2016
USD ($)
Dec. 31, 2023
USD ($)
Dec. 31, 2009
USD ($)
Dec. 31, 2004
USD ($)
Dec. 31, 2023
USD ($)
PARI Agreement                      
Collaboration Agreements                      
Initial term of contract manufacturing agreement       15 years              
Additional term of contract manufacturing agreement       5 years              
PARI Agreement | Minimum                      
Collaboration Agreements                      
Written notice period required for termination of contract manufacturing agreement       1 year              
PARI Agreement | Milestone, New Drug Application                      
Collaboration Agreements                      
PARI milestone upon FDA approval | €           € 1.0          
PARI Agreement | Milestone, FDA Approval                      
Collaboration Agreements                      
PARI milestone upon FDA approval | €           1.5          
PARI Agreement | Milestone, EMA Approval                      
Collaboration Agreements                      
PARI milestone upon FDA approval | €           € 0.5          
PPD Development, L.P. Agreement                      
Collaboration Agreements                      
Initial term of clinical development services agreement   5 years                  
Written notice termination term of clinical development services agreement   30 days                  
License Agreement with AstraZeneca                      
Collaboration Agreements                      
Collaborative arrangement, additional payment             $ 12.5        
Royalty payment     $ 35.0                
License Agreement with AstraZeneca | Maximum                      
Collaboration Agreements                      
Aggregate payment upon the achievement of certain clinical milestones     60.0                
Additional contingent payments upon second indication to develop INS1007     42.5                
License Agreement with AstraZeneca | License and Service                      
Collaboration Agreements                      
Annual net sales     $ 1,000.0                
License Agreement with AstraZeneca | Research and development expenses                      
Collaboration Agreements                      
Upfront payment             $ 30.0        
Phase 3 study payment $ 12.5                    
Resilience Biotechnologies                      
Collaboration Agreements                      
Initial term of contract manufacturing agreement         5 years            
Written notice period required for termination of contract manufacturing agreement         2 years            
Manufacturing scale (in kilograms) | kg         200            
Period of each automatic renewal of contract manufacturing agreement         2 years            
Minimum obligation         $ 6.0            
CFFT                      
Collaboration Agreements                      
Compensation earned under research funding agreements with CFFT                 $ 2.2 $ 1.7  
Royalty payable on approval of ARIKAYCE as commercialized drug               $ 13.4     $ 13.4
Royalty expense paid for ARIKAYCE approval                     7.4
Period for meeting sales milestones for additional royalty payments               5 years      
Royalty payable on meeting certain sales milestones               $ 3.9     $ 3.9
Additional global sales milestone payments               $ 1.7