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Accounts Payable and Accrued Liabilities (Details) - USD ($) $ in Thousands | Jun. 30, 2024 | Dec. 31, 2023
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Payables and Accruals [Abstract] |  |
Accounts payable and other accrued operating expenses | $ 51,363 | $ 65,393
Accrued clinical trial expenses | 22,581 | 23,711
Accrued professional fees | 16,114 | 13,885
Accrued technical operation expenses | 11,097 | 9,187
Accrued compensation and employee related costs | 42,198 | 48,933
Accrued royalty and milestones payable | 7,288 | 5,674
Accrued interest payable | 2,175 | 2,175
Revenue Interest Payments payable | 3,613 | 3,347
Accrued sales allowances and related costs | 14,479 | 10,937
Accrued France ATU reimbursement payable | 17,188 | 14,685
Deferred and contingent consideration | 81,600 | 6,700
Accrued milestone payment to AstraZeneca | 12,500 | 0
Other accrued liabilities | 8,648 | 10,360
Total accounts payable and accrued liabilities | $ 290,844 | $ 214,987

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