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Fair Value Measurements - Narrative (Details) $ in Thousands |  | 1 Months Ended | 3 Months Ended | 6 Months Ended |  |  |  |  |
--- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Aug. 04, 2021 shares | Aug. 31, 2023 shares | Oct. 31, 2022 USD ($) | Aug. 31, 2022 shares | Aug. 31, 2021 sale shares | Sep. 30, 2023 shares | Sep. 30, 2022 shares | Dec. 31, 2021 shares | Jun. 30, 2024 USD ($) | Jun. 30, 2023 USD ($) | Sep. 01, 2025 | Dec. 31, 2023 USD ($) | Oct. 01, 2022 | May 31, 2021 USD ($) | Jan. 31, 2018 USD ($)
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Maturities of marketable securities |  |  |  |  |  |  |  |  | $ 300,000 | $ 65,000 |  |  |  |  |
Deferred consideration |  |  |  |  |  |  |  |  | 12,400 |  |  |  |  |  |
Non-current contingent consideration |  |  |  |  |  |  |  |  | 101,500 |  |  | $ 84,600 |  |  |
Accounts Payable and Accrued Liabilities |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deferred consideration |  |  |  |  |  |  |  |  | $ 12,400 |  |  |  |  |  |
0.75% Convertible Senior Notes Due 2028 | Convertible notes |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Interest rate (as a percent) |  |  |  |  |  |  |  |  | 0.75% |  |  |  |  |  |
Convertible senior notes |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 371,600 |
Original Term Loan balance |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 575,000 |
1.75% Convertible Senior Notes Due 2025 | Convertible notes |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Interest rate (as a percent) |  |  |  |  |  |  |  |  | 1.75% |  |  |  |  |  |
Convertible senior notes |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 309,100
Original Term Loan balance |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 450,000
Royalty Agreements | ARIKAYCE Global Net Sales |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Royalty percentage |  |  |  |  |  |  |  |  |  |  |  |  | 4.00% |  |
Royalty Agreements | Brensocatib Global Net Sales |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Royalty percentage |  |  | 75.00% |  |  |  |  |  |  |  |  |  |  |  |
Royalty Agreements | Forecast | ARIKAYCE Global Net Sales |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Royalty percentage |  |  |  |  |  |  |  |  |  |  | 4.50% |  |  |  |
Royalty Agreements | Secured Debt |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from royalty financing |  |  | $ 150,000 |  |  |  |  |  |  |  |  |  |  |  |
Original Term Loan balance |  |  | 150,000 |  |  |  |  |  |  |  |  |  |  |  |
Interest payments |  |  | $ 150,000 |  |  |  |  |  |  |  |  |  |  |  |
Probabilities of success |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Weighted average probability of success |  |  |  |  |  |  |  |  | 0.42 |  |  |  |  |  |
Recurring Basis | Level 3 | Estimate of Fair Value Measurement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Marketable securities |  |  |  |  |  |  |  |  |  |  |  | 0 |  |  |
Deferred consideration |  |  |  |  |  |  |  |  | $ 0 |  |  | 0 |  |  |
Recurring Basis | Level 2 | Estimate of Fair Value Measurement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Marketable securities |  |  |  |  |  |  |  |  |  |  |  | 0 |  |  |
Deferred consideration |  |  |  |  |  |  |  |  | 12,400 |  |  | $ 5,700 |  |  |
Recurring Basis | Level 2 | 0.75% Convertible Senior Notes Due 2028 | Convertible notes | Estimate of Fair Value Measurement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Convertible senior notes |  |  |  |  |  |  |  |  | 1,200,000 |  |  |  |  |  |
Recurring Basis | Level 2 | 1.75% Convertible Senior Notes Due 2025 | Convertible notes | Estimate of Fair Value Measurement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Convertible senior notes |  |  |  |  |  |  |  |  | 384,500 |  |  |  |  |  |
Motus |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued in acquisition (in shares) | shares | 2,889,367 | 177,203 |  | 171,427 |  | 177,203 | 171,427 | 2,889,367 |  |  |  |  |  |  |
Shares issued upon milestone achievements (in shares) | shares |  |  |  |  | 5,348,572 |  |  |  |  |  |  |  |  |  |
Motus | Development and regulatory milestones |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds of sale of priority review voucher obligated to pay to equity holders, percentage |  |  |  |  | 50.00% |  |  |  |  |  |  |  |  |  |
Average sales prices of publicly disclosed priority review voucher sales obligated to pay equity holders, percentage |  |  |  |  | 50.00% |  |  |  |  |  |  |  |  |  |
Number of publicly disclosed sales used to determine average sales price owed to equity holders | sale |  |  |  |  | 3 |  |  |  |  |  |  |  |  |  |
Motus | First Anniversary of Closing Date |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued in acquisition (in shares) | shares |  |  |  |  | 184,433 |  |  |  |  |  |  |  |  |  |
Motus | Second Anniversary of Closing Date |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued in acquisition (in shares) | shares |  |  |  |  | 184,433 |  |  |  |  |  |  |  |  |  |
Motus | Third Anniversary of Closing Date |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued in acquisition (in shares) | shares |  |  |  |  | 184,433 |  |  |  |  |  |  |  |  |  |
Motus | Level 3 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Current contingent consideration |  |  |  |  |  |  |  |  | 101,500 |  |  |  |  |  |
Non-current contingent consideration |  |  |  |  |  |  |  |  | $ 68,200 |  |  |  |  |  |
AlgaeneX |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued upon milestone achievements (in shares) | shares | 368,867 |  |  |  |  |  |  |  |  |  |  |  |  |  |

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