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Consolidated Statements of Shareholders' Equity (Deficit) (unaudited) - USD ($) shares in Thousands, $ in Thousands | Total | Common Stock | Additional Paid-in Capital | Accumulated Deficit | Accumulated Other Comprehensive Income (Loss)
--- | --- | --- | --- | --- | ---
Beginning balance (in shares) at Dec. 31, 2022 |  | 135,654 |  |  |
Beginning balance at Dec. 31, 2022 | $ 87,951 | $ 1,357 | $ 2,782,416 | $ (2,696,578) | $ 756
Comprehensive loss: |  |  |  |  |
Net loss | (404,573) |  |  | (404,573) |
Other comprehensive loss | (2,007) |  |  |  | (2,007)
Exercise of stock options and ESPP shares (in shares) |  | 595 |  |  |
Exercise of stock options and ESPP shares | 8,422 | $ 6 | 8,416 |  |
Net proceeds from issuance of common stock (in shares) |  | 2,028 |  |  |
Net proceeds from issuance of common stock | 38,014 | $ 20 | 37,994 |  |
Issuance of common stock for vesting of RSUs (in shares) |  | 542 |  |  |
Issuance of common stock for vesting of RSUs | 6 | $ 6 |  |  |
Issuance of common stock for asset acquisitions (in shares) |  | 3,931 |  |  |
Issuance of common stock for asset acquisitions | 81,640 | $ 39 | 81,601 |  |
Stock-based compensation expense | 34,802 |  | 34,802 |  |
Ending balance (in shares) at Jun. 30, 2023 |  | 142,750 |  |  |
Ending balance at Jun. 30, 2023 | (155,745) | $ 1,428 | 2,945,229 | (3,101,151) | (1,251)
Beginning balance (in shares) at Mar. 31, 2023 |  | 136,429 |  |  |
Beginning balance at Mar. 31, 2023 | (44,653) | $ 1,364 | 2,809,242 | (2,856,342) | 1,083
Comprehensive loss: |  |  |  |  |
Net loss | (244,809) |  |  | (244,809) |
Other comprehensive loss | (2,334) |  |  |  | (2,334)
Exercise of stock options and ESPP shares (in shares) |  | 513 |  |  |
Exercise of stock options and ESPP shares | 7,283 | $ 5 | 7,278 |  |
Net proceeds from issuance of common stock (in shares) |  | 2,028 |  |  |
Net proceeds from issuance of common stock | 38,014 | $ 20 | 37,994 |  |
Issuance of common stock for vesting of RSUs (in shares) |  | 349 |  |  |
Issuance of common stock for vesting of RSUs | 5 | $ 5 |  |  |
Issuance of common stock for asset acquisitions (in shares) |  | 3,431 |  |  |
Issuance of common stock for asset acquisitions | 72,390 | $ 34 | 72,356 |  |
Stock-based compensation expense | 18,359 |  | 18,359 |  |
Ending balance (in shares) at Jun. 30, 2023 |  | 142,750 |  |  |
Ending balance at Jun. 30, 2023 | (155,745) | $ 1,428 | 2,945,229 | (3,101,151) | (1,251)
Beginning balance (in shares) at Dec. 31, 2023 |  | 147,978 |  |  |
Beginning balance at Dec. 31, 2023 | (331,923) | $ 1,480 | 3,113,487 | (3,446,145) | (745)
Comprehensive loss: |  |  |  |  |
Net loss | (457,700) |  |  | (457,700) |
Other comprehensive loss | (2,085) |  |  |  | (2,085)
Exercise of stock options and ESPP shares (in shares) |  | 3,279 |  |  |
Exercise of stock options and ESPP shares | 72,623 | $ 33 | 72,590 |  |
Net proceeds from issuance of common stock (in shares) |  | 14,515 |  |  |
Net proceeds from issuance of common stock | 713,158 | $ 145 | 713,013 |  |
Issuance of common stock for vesting of RSUs (in shares) |  | 895 |  |  |
Issuance of common stock for vesting of RSUs | 9 | $ 9 |  |  |
Stock-based compensation expense | 44,736 |  | 44,736 |  |
Ending balance (in shares) at Jun. 30, 2024 |  | 166,667 |  |  |
Ending balance at Jun. 30, 2024 | 38,818 | $ 1,667 | 3,943,826 | (3,903,845) | (2,830)
Beginning balance (in shares) at Mar. 31, 2024 |  | 148,561 |  |  |
Beginning balance at Mar. 31, 2024 | (464,808) | $ 1,486 | 3,138,578 | (3,603,236) | (1,636)
Comprehensive loss: |  |  |  |  |
Net loss | (300,609) |  |  | (300,609) |
Other comprehensive loss | (1,194) |  |  |  | (1,194)
Exercise of stock options and ESPP shares (in shares) |  | 3,062 |  |  |
Exercise of stock options and ESPP shares | 68,571 | $ 31 | 68,540 |  |
Net proceeds from issuance of common stock (in shares) |  | 14,515 |  |  |
Net proceeds from issuance of common stock | 713,567 | $ 145 | 713,422 |  |
Issuance of common stock for vesting of RSUs (in shares) |  | 529 |  |  |
Issuance of common stock for vesting of RSUs | 5 | $ 5 |  |  |
Stock-based compensation expense | 23,286 |  | 23,286 |  |
Ending balance (in shares) at Jun. 30, 2024 |  | 166,667 |  |  |
Ending balance at Jun. 30, 2024 | $ 38,818 | $ 1,667 | $ 3,943,826 | $ (3,903,845) | $ (2,830)

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