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Accounts Payable and Accrued Liabilities (Details) - USD ($) $ in Thousands | Jun. 30, 2026 | Dec. 31, 2025
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Payables and Accruals [Abstract] |  |
Accounts payable and other accrued operating expenses | $ 74,555 | $ 79,907
Accrued clinical trial expenses | 34,443 | 34,329
Accrued professional fees | 25,014 | 23,658
Accrued technical operation expenses | 21,730 | 22,533
Accrued compensation and employee related costs | 61,579 | 111,514
Accrued royalty and milestones payable | 37,774 | 17,101
Revenue Interest Payments payable | 7,553 | 6,449
Accrued sales allowances and related costs | 146,373 | 70,869
Accrued French rebate payable | 9,062 | 6,960
Contingent consideration | 0 | 57,799
Accrued milestone payment to AstraZeneca | 0 | 15,000
Other accrued liabilities | 10,846 | 9,941
Total accounts payable and accrued liabilities | $ 428,929 | $ 456,060

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