Exhibit 21.1

SUBSIDIARIES OF DTE ENERGY COMPANY
DTE Energy Company’s principal subsidiaries as of December 31, 2022 are listed below. All other subsidiaries, if considered in the aggregate as a single subsidiary, would not constitute a significant subsidiary.
SubsidiaryState of Incorporation
1.DTE Electric CompanyMichigan
2.DTE Electric Holdings, LLCMichigan
3.DTE Energy Trading, Inc.Michigan
4.DTE Enterprises, Inc.Michigan
5.DTE Gas CompanyMichigan
6.DTE Gas Holdings, Inc.Michigan