v3.8.0.1
Consolidated Statements of Operations - USD ($)
shares in Millions, $ in Millions
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Product revenue $ 718.5 $ 573.3 $ 400.7
Development grant and other revenue 0.0 0.0 1.3
Total revenue 718.5 573.3 402.0
Cost of sales 226.4 194.9 123.6
Gross profit 492.1 378.4 278.4
Operating expenses      
Research and development 185.4 156.1 137.5
Selling, general and administrative 349.2 286.2 198.0
Total operating expenses 534.6 442.3 335.5
Operating loss (42.5) (63.9) (57.1)
Other income (expense) 3.4 (0.7) 0.0
Interest income 3.3 0.4 0.0
Interest expense (12.8) (0.7) (0.4)
Loss before income taxes (48.6) (64.9) (57.5)
Income tax expense (1.6) (0.7) (0.1)
Net loss $ (50.2) $ (65.6) $ (57.6)
Basic and diluted net loss per share $ (0.58) $ (0.78) $ (0.72)
Shares used to compute basic and diluted net loss per share 86.3 83.6 79.8