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Organization and Summary of Significant Accounting Policies - Additional Information (Detail) - USD ($)
3 Months Ended 6 Months Ended
Mar. 08, 2018
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Dec. 31, 2017
Organization And Summary Of Significant Accounting Policies [Line Items]            
Accumulated deficit   $ 665,800,000   $ 665,800,000   $ 671,800,000
Accrued Healthcare Obligations   2,700,000   2,700,000    
Cash, cash equivalents and short-term investments   606,100,000   606,100,000    
Working capital   665,200,000   665,200,000    
Share-based compensation   25,600,000 $ 25,300,000 50,200,000 $ 55,900,000  
Stock-based compensation, unvested restricted stock units   $ 172,600,000   $ 172,600,000    
Sales returns coverage period       30 days    
Performance Shares [Member]            
Organization And Summary Of Significant Accounting Policies [Line Items]            
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period 43,370          
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period       3 years    
Performance Shares [Member] | Minimum            
Organization And Summary Of Significant Accounting Policies [Line Items]            
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage 0.00%          
Performance Shares [Member] | Maximum            
Organization And Summary Of Significant Accounting Policies [Line Items]            
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage 200.00%          
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost $ 4,500,000.0