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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2019
Income Tax Disclosure [Abstract]  
Schedule of Income (Loss) before Income Taxes Subject to Taxes
Income (loss) before income taxes subject to taxes in the following jurisdictions is as follows:
 
Twelve Months Ended
December 31,
(In millions)
2019
 
2018
 
2017
United States
$
119.1

 
$
(28.3
)
 
$
12.4

Outside of the United States
(14.9
)
 
(98.2
)
 
(61.0
)
Total
$
104.2

 
$
(126.5
)
 
$
(48.6
)







Schedule of Components of Income Tax Expense (Benefit)
Significant components of the provision for income taxes are as follows:
 
Twelve Months Ended
December 31, 2019
(In millions)
2019
 
2018
 
2017
Current:
 
 
 
 
 
Federal
$

 
$

 
$

State
1.0

 
2.7

 
0.1

Foreign
1.9

 
0.1

 
1.5

Total current income taxes
2.9

 
2.8

 
1.6

Deferred:
 
 
 
 
 
Federal

 
(1.7
)
 

State

 
(0.5
)
 

Foreign
0.2

 

 

Total deferred income taxes
0.2

 
(2.2
)
 

Total
$
3.1

 
$
0.6

 
$
1.6


Schedule of Deferred Tax Assets and Liabilities
Significant components of our deferred tax assets as of December 31, 2019 and 2018 are shown below. A valuation allowance of approximately $332.2 million has been established as of December 31, 2019 to offset the deferred tax assets, as realization of such assets is uncertain. We maintain a deferred tax liability related to indefinite-lived intangible assets that is not netted against the deferred tax assets. Reversal of the taxable temporary difference for these intangible assets cannot serve as a source of income for realization of the deferred tax assets because the deferred tax liability will not reverse until the intangible assets are sold or written down due to impairment.
 
December 31,
(In millions)
2019
 
2018
Deferred tax assets:
 
 
 
     Net operating loss carryforwards
$
127.4

 
$
162.0

     Capitalized research and development expenses
57.1

 
62.1

     Tax credits
78.6

 
59.0

     Share-based compensation
10.9

 
12.5

     Fixed and intangible assets
14.0

 
16.0

     Accrued liabilities and reserves
62.0

 
22.5

     Convertible Debt
1.7

 

        Total gross deferred tax assets
351.7

 
334.1

        Less: valuation allowance
(332.2
)
 
(330.1
)
        Total net deferred tax assets
19.5

 
4.0

Deferred tax liabilities:
 
 
 
     Fixed assets and acquired intangibles assets
(19.6
)
 
(3.8
)
     Convertible debt discount

 
(0.1
)
        Total deferred tax liabilities
(19.6
)
 
(3.9
)
Net deferred tax assets (liabilities)
$
(0.1
)
 
$
0.1


Schedule of Reconciliation between Effective Tax Rate and Statutory Rate
The reconciliation between our effective tax rate on income (loss) from continuing operations and the statutory rate is as follows:
 
Twelve Months Ended
December 31,
(In millions)
2019
 
2018
 
2017
Income taxes at statutory rates
$
21.9

 
$
(26.6
)
 
$
(17.0
)
State income tax, net of federal benefit
(2.3
)
 
(5.5
)
 
(0.7
)
Permanent items
1.0

 
1.3

 
0.7

Research and development credits
(10.8
)
 
(11.7
)
 
(13.3
)
Foreign rate differential
5.6

 
3.7

 
5.4

Stock and officers compensation
(14.7
)
 
(5.1
)
 
(10.4
)
Rate change

 

 
(0.1
)
Unrecognized tax benefits

 

 
(15.4
)
Impact of adoption of ASU 2016-16

 
(13.3
)
 

Impact of Tax Cuts and Jobs Act of 2017

 
(0.4
)
 
105.7

Other
(1.0
)
 
1.3

 
(2.2
)
Change in valuation allowance
3.4

 
56.9

 
(51.1
)
Income taxes at effective rates
$
3.1

 
$
0.6

 
$
1.6


Schedule of Unrecognized Tax Benefits
The following table summarizes the activity related to our gross unrecognized tax benefits:
(In millions)
 
Balance at January 1, 2017
$
39.8

Decreases related to prior year tax positions
(14.9
)
Increases related to current year tax positions
3.3

Decrease related to Tax Cuts and Jobs Act of 2017
(5.4
)
Balance at December 31, 2017
22.8

Decreases related to prior year tax positions
(0.3
)
Increases related to current year tax positions
3.4

Balance at December 31, 2018
25.9

Decreases related to prior year tax positions
(0.9
)
Increases related to current year tax positions
4.5

Balance at December 31, 2019
$
29.5