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Consolidated Statements of Operations - USD ($)
shares in Millions, $ in Millions
 12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Income Statement [Abstract]      
Revenue $ 1,476.0 $ 1,031.6 $ 718.5
Cost of sales 544.5 367.7 226.4
Gross profit 931.5 663.9 492.1
Operating expenses      
Research and development 273.5 199.7 185.4
Collaborative research and development fee 0.0 217.7 0.0
Selling, general and administrative 515.7 432.8 349.2
Total operating expenses 789.2 850.2 534.6
Operating income (loss) 142.3 (186.3) (42.5)
Interest expense (60.3) (22.7) (12.8)
Income (loss) from equity investments (4.2) 80.1 0.0
Interest and other income, net 26.4 2.4 6.7
Income (loss) before income taxes 104.2 (126.5) (48.6)
Income tax expense 3.1 0.6 1.6
Net income (loss) $ 101.1 $ (127.1) $ (50.2)
Basic net income (loss) per share (USD per share) $ 1.11 $ (1.44) $ (0.58)
Shares used to compute basic net income (loss) per share (shares) 91.1 88.2 86.3
Diluted net income (loss) per share (USD per share) $ 1.10 $ (1.44) $ (0.58)
Shares used to compute diluted net income (loss) per share (shares) 92.3 88.2 86.3