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Fair Value Measurements - Fair Value Hierarchy of Financial Assets (Details) - USD ($) $ in Millions | Dec. 31, 2021 | Dec. 31, 2020
--- | --- | ---
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |
Cash equivalents | $ 831.4 | $ 641.5
Debt securities, available-for-sale | 1,678.6 | 1,890.1
Other assets | 7.0 | 3.4
Total assets measured at fair value on a recurring basis | 2,517.0 | 2,535.0
Level 1 |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |
Cash equivalents | 791.4 | 491.5
Debt securities, available-for-sale | 0.0 | 0.0
Other assets | 7.0 | 3.4
Total assets measured at fair value on a recurring basis | 798.4 | 494.9
Level 2 |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |
Cash equivalents | 40.0 | 150.0
Debt securities, available-for-sale | 1,678.6 | 1,890.1
Other assets | 0.0 | 0.0
Total assets measured at fair value on a recurring basis | 1,718.6 | 2,040.1
Level 3 |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |
Cash equivalents | 0.0 | 0.0
Debt securities, available-for-sale | 0.0 | 0.0
Other assets | 0.0 | 0.0
Total assets measured at fair value on a recurring basis | 0.0 | 0.0
U.S. government agencies |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |
Debt securities, available-for-sale | 1,210.6 | 1,570.4
U.S. government agencies | Level 1 |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |
Debt securities, available-for-sale | 0.0 | 0.0
U.S. government agencies | Level 2 |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |
Debt securities, available-for-sale | 1,210.6 | 1,570.4
U.S. government agencies | Level 3 |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |
Debt securities, available-for-sale | 0.0 | 0.0
Commercial paper |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |
Debt securities, available-for-sale | 189.7 | 258.8
Commercial paper | Level 1 |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |
Debt securities, available-for-sale | 0.0 | 0.0
Commercial paper | Level 2 |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |
Debt securities, available-for-sale | 189.7 | 258.8
Commercial paper | Level 3 |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |
Debt securities, available-for-sale | 0.0 | 0.0
Corporate debt |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |
Debt securities, available-for-sale | 224.3 | 60.9
Corporate debt | Level 1 |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |
Debt securities, available-for-sale | 0.0 | 0.0
Corporate debt | Level 2 |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |
Debt securities, available-for-sale | 224.3 | 60.9
Corporate debt | Level 3 |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |
Debt securities, available-for-sale | 0.0 | $ 0.0
Supranationals |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |
Debt securities, available-for-sale | 54.0 |
Supranationals | Level 1 |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |
Debt securities, available-for-sale | 0.0 |
Supranationals | Level 2 |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |
Debt securities, available-for-sale | 54.0 |
Supranationals | Level 3 |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |
Debt securities, available-for-sale | $ 0.0 |

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