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Balance Sheet Details - Short-term Marketable Securities, Available-for-Sale (Details) - USD ($) $ in Millions	Dec. 31, 2021	Dec. 31, 2020
Condensed Financial Statements, Captions [Line Items]
Amortized Cost	$ 1,680.6	$ 1,890.0
Gross Unrealized Gains	0.0	0.2
Gross Unrealized Losses	(2.0)	(0.1)
Estimated Market Value	1,678.6	1,890.1
U.S. government agencies
Condensed Financial Statements, Captions [Line Items]
Amortized Cost	1,212.1	1,570.4
Gross Unrealized Gains	0.0	0.1
Gross Unrealized Losses	(1.5)	(0.1)
Estimated Market Value	1,210.6	1,570.4
Commercial paper
Condensed Financial Statements, Captions [Line Items]
Amortized Cost	189.8	258.7
Gross Unrealized Gains	0.0	0.1
Gross Unrealized Losses	(0.1)	0.0
Estimated Market Value	189.7	258.8
Corporate debt
Condensed Financial Statements, Captions [Line Items]
Amortized Cost	224.6	60.9
Gross Unrealized Gains	0.0	0.0
Gross Unrealized Losses	(0.3)	0.0
Estimated Market Value	224.3	$ 60.9
Supranationals
Condensed Financial Statements, Captions [Line Items]
Amortized Cost	54.1
Gross Unrealized Gains	0.0
Gross Unrealized Losses	(0.1)
Estimated Market Value	$ 54.0

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