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Fair Value Measurements - Summary (Details) - USD ($) $ in Millions	Sep. 30, 2022	Dec. 31, 2021
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Cash equivalents	$ 478.1	$ 831.4
Debt securities, available-for-sale	1,673.8	1,678.6
Other assets	8.9	7.0
Total assets measured at fair value on a recurring basis	2,160.8	2,517.0
U.S. government agencies
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Debt securities, available-for-sale	1,327.0	1,210.6
Commercial paper
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Debt securities, available-for-sale	201.8	189.7
Corporate debt
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Debt securities, available-for-sale	131.5	224.3
Supranationals
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Debt securities, available-for-sale	13.5	54.0
Level 1
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Cash equivalents	478.1	791.4
Debt securities, available-for-sale	0.0	0.0
Other assets	8.9	7.0
Total assets measured at fair value on a recurring basis	487.0	798.4
Level 1 | U.S. government agencies
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Debt securities, available-for-sale	0.0	0.0
Level 1 | Commercial paper
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Debt securities, available-for-sale	0.0	0.0
Level 1 | Corporate debt
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Debt securities, available-for-sale	0.0	0.0
Level 1 | Supranationals
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Debt securities, available-for-sale	0.0	0.0
Level 2
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Cash equivalents	0.0	40.0
Debt securities, available-for-sale	1,673.8	1,678.6
Other assets	0.0	0.0
Total assets measured at fair value on a recurring basis	1,673.8	1,718.6
Level 2 | U.S. government agencies
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Debt securities, available-for-sale	1,327.0	1,210.6
Level 2 | Commercial paper
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Debt securities, available-for-sale	201.8	189.7
Level 2 | Corporate debt
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Debt securities, available-for-sale	131.5	224.3
Level 2 | Supranationals
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Debt securities, available-for-sale	13.5	54.0
Level 3
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Cash equivalents	0.0	0.0
Debt securities, available-for-sale	0.0	0.0
Other assets	0.0	0.0
Total assets measured at fair value on a recurring basis	0.0	0.0
Level 3 | U.S. government agencies
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Debt securities, available-for-sale	0.0	0.0
Level 3 | Commercial paper
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Debt securities, available-for-sale	0.0	0.0
Level 3 | Corporate debt
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Debt securities, available-for-sale	0.0	0.0
Level 3 | Supranationals
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Debt securities, available-for-sale	$ 0.0	$ 0.0

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Fair value portion of probable future economic benefits obtained or controlled by an entity as a result of past transactions or events.

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Amount of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
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Amount of short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates. Excludes cash and cash equivalents within disposal group and discontinued operation.

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