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Balance Sheet Details - Short-Term Marketable Securities (Details) - USD ($) $ in Millions	Sep. 30, 2022	Dec. 31, 2021
Debt securities, available-for-sale:
Amortized Cost	$ 1,684.7	$ 1,680.6
Gross Unrealized Gains	0.0	0.0
Gross Unrealized Losses	(10.9)	(2.0)
Estimated Market Value	1,673.8	1,678.6
U.S. government agencies
Debt securities, available-for-sale:
Amortized Cost	1,336.8	1,212.1
Gross Unrealized Gains	0.0	0.0
Gross Unrealized Losses	(9.8)	(1.5)
Estimated Market Value	1,327.0	1,210.6
Commercial paper
Debt securities, available-for-sale:
Amortized Cost	202.0	189.8
Gross Unrealized Gains	0.0	0.0
Gross Unrealized Losses	(0.2)	(0.1)
Estimated Market Value	201.8	189.7
Corporate debt
Debt securities, available-for-sale:
Amortized Cost	132.4	224.6
Gross Unrealized Gains	0.0	0.0
Gross Unrealized Losses	(0.9)	(0.3)
Estimated Market Value	131.5	224.3
Supranationals
Debt securities, available-for-sale:
Amortized Cost	13.5	54.1
Gross Unrealized Gains	0.0	0.0
Gross Unrealized Losses	0.0	(0.1)
Estimated Market Value	$ 13.5	$ 54.0

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Amount, before tax, of unrealized gain in accumulated other comprehensive income (AOCI) on investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).

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