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Business Segment and Geographic Information - Segment Revenue, Segment Profit or Loss, and Significant Segment Expenses (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Segment Reporting [Abstract]        
Revenue $ 1,209.3 $ 994.2 $ 3,402.4 $ 2,919.5
Cost of sales 477.9 400.4 1,393.2 1,137.1
Payroll related expenses 233.2 179.9 675.4 569.2
Stock-based compensation expense 44.1 39.8 116.4 115.7
Marketing expense 75.7 65.7 224.9 213.6
Travel related expenses 15.2 14.5 49.1 51.6
Supply expenses and clinical trials 17.7 18.2 45.8 50.9
Consulting & professional fees 33.1 59.9 100.9 175.1
Equipment, office & facility expenses 22.8 20.3 66.8 63.4
IT software and data 36.8 33.2 107.9 96.6
Depreciation and amortization 9.6 9.5 28.1 30.6
Other segment items 0.7 0.8 5.1 4.6
Operating income 242.5 152.0 588.8 411.1
Other income, net 109.8 25.4 158.9 86.6
Income tax expense 68.5 42.8 178.7 73.2
Net income 283.8 134.6 569.0 424.5
Depreciation and amortization 63.6 55.3 186.6 159.9
Expenditures for long-lived assets 80.5 111.2 261.6 234.2
Deferred income tax expense (benefit) 118.0 (11.6) 103.3 (68.1)
Net (gains) losses on equity investments $ (82.7) $ (0.4) $ (78.1) $ 1.4