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Business Combination (Details) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Dec. 31, 2016
Business Acquisition [Line Items]          
Goodwill $ 538,418 $ 482,144 $ 538,418 $ 482,144 $ 476,378
Amortization of Intangible Assets 2,900 $ 2,200 7,900 $ 5,800  
BIOTIX [Member]          
Business Acquisition [Line Items]          
Payments to Acquire Businesses, Gross     105,000    
Business Combination, Contingent Consideration Arrangements, Range of Outcomes, Value, High 65,000   65,000    
Business Combination, Contingent Consideration, Liability 30,700   30,700    
Goodwill 51,300   51,300    
Amortization of Intangible Assets     3,700    
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Net 19,200   19,200    
Other Acquisitions [Member]          
Business Acquisition [Line Items]          
Payments to Acquire Businesses, Gross     0    
Goodwill 0   0    
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Net $ 0   $ 0    
Acquired Finite-lived Intangible Assets, Weighted Average Useful Life     12 years    
Customer Relationships [Member] | BIOTIX [Member]          
Business Acquisition [Line Items]          
Finite-lived Intangible Assets Acquired     $ 49,500    
Technology-Based Intangible Assets [Member] | BIOTIX [Member]          
Business Acquisition [Line Items]          
Finite-lived Intangible Assets Acquired     8,000    
Technology-Based Intangible Assets [Member] | Other Acquisitions [Member]          
Business Acquisition [Line Items]          
Finite-lived Intangible Assets Acquired     0    
Trade Names [Member] | BIOTIX [Member]          
Business Acquisition [Line Items]          
Indefinite-lived Intangible Assets Acquired     7,100    
Other Intangible Assets [Member] | BIOTIX [Member]          
Business Acquisition [Line Items]          
Finite-lived Intangible Assets Acquired     $ 600    
Minimum [Member] | BIOTIX [Member]          
Business Acquisition [Line Items]          
Acquired Finite-lived Intangible Assets, Weighted Average Useful Life     5 years    
Maximum [Member] | BIOTIX [Member]          
Business Acquisition [Line Items]          
Acquired Finite-lived Intangible Assets, Weighted Average Useful Life     18 years