<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with Wdesk from Workiva-->
<!--Copyright 2023 Workiva-->
<!--r:59c8bde4-81f0-4ce6-85fd-44572a588b21,g:2cde0c7b-f2e0-43cc-aa96-c5634cd16f43-->
<xs:schema xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:mtd="http://www.mt.com/20221231" xmlns:xbrli="http://www.xbrl.org/2003/instance" xmlns:dtr-types="http://www.xbrl.org/dtr/type/2020-01-21" attributeFormDefault="unqualified" elementFormDefault="qualified" targetNamespace="http://www.mt.com/20221231">
  <xs:import namespace="http://fasb.org/srt/2022" schemaLocation="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd"/>
  <xs:import namespace="http://fasb.org/us-gaap/2022" schemaLocation="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd"/>
  <xs:import namespace="http://www.w3.org/1999/xlink" schemaLocation="http://www.xbrl.org/2003/xlink-2003-12-31.xsd"/>
  <xs:import namespace="http://www.xbrl.org/2003/instance" schemaLocation="http://www.xbrl.org/2003/xbrl-instance-2003-12-31.xsd"/>
  <xs:import namespace="http://www.xbrl.org/2003/linkbase" schemaLocation="http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd"/>
  <xs:import namespace="http://www.xbrl.org/dtr/type/2020-01-21" schemaLocation="https://www.xbrl.org/dtr/type/2020-01-21/types.xsd"/>
  <xs:import namespace="http://xbrl.sec.gov/country/2022" schemaLocation="https://xbrl.sec.gov/country/2022/country-2022.xsd"/>
  <xs:import namespace="http://xbrl.sec.gov/dei/2022" schemaLocation="https://xbrl.sec.gov/dei/2022/dei-2022.xsd"/>
  <xs:annotation>
    <xs:appinfo>
      <link:linkbaseRef xmlns:xlink="http://www.w3.org/1999/xlink" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="mtd-20221231_lab.xml" xlink:role="http://www.xbrl.org/2003/role/labelLinkbaseRef" xlink:type="simple"/>
      <link:linkbaseRef xmlns:xlink="http://www.w3.org/1999/xlink" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="mtd-20221231_pre.xml" xlink:role="http://www.xbrl.org/2003/role/presentationLinkbaseRef" xlink:type="simple"/>
      <link:linkbaseRef xmlns:xlink="http://www.w3.org/1999/xlink" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="mtd-20221231_cal.xml" xlink:role="http://www.xbrl.org/2003/role/calculationLinkbaseRef" xlink:type="simple"/>
      <link:linkbaseRef xmlns:xlink="http://www.w3.org/1999/xlink" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="mtd-20221231_def.xml" xlink:role="http://www.xbrl.org/2003/role/definitionLinkbaseRef" xlink:type="simple"/>
      <link:roleType id="DocumentandEntityInformationDocument" roleURI="http://www.mt.com/role/DocumentandEntityInformationDocument">
        <link:definition>0000001 - Document - Document and Entity Information Document</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="AuditInformation" roleURI="http://www.mt.com/role/AuditInformation">
        <link:definition>0000002 - Document - Audit Information</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ConsolidatedStatementsofOperations" roleURI="http://www.mt.com/role/ConsolidatedStatementsofOperations">
        <link:definition>0000003 - Statement - Consolidated Statements of Operations</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StatementofComprehensiveIncome" roleURI="http://www.mt.com/role/StatementofComprehensiveIncome">
        <link:definition>0000004 - Statement - Statement of Comprehensive Income</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ConsolidatedBalanceSheets" roleURI="http://www.mt.com/role/ConsolidatedBalanceSheets">
        <link:definition>0000005 - Statement - Consolidated Balance Sheets</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ConsolidatedBalanceSheetsParentheticals" roleURI="http://www.mt.com/role/ConsolidatedBalanceSheetsParentheticals">
        <link:definition>0000006 - Statement - Consolidated Balance Sheets (Parentheticals)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ConsolidatedStatementsofShareholdersEquity" roleURI="http://www.mt.com/role/ConsolidatedStatementsofShareholdersEquity">
        <link:definition>0000007 - Statement - Consolidated Statements of Shareholders' Equity</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ConsolidatedStatementsofCashFlows" roleURI="http://www.mt.com/role/ConsolidatedStatementsofCashFlows">
        <link:definition>0000008 - Statement - Consolidated Statements of Cash Flows</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StatementofFinancialPositionClassified" roleURI="http://www.mt.com/role/StatementofFinancialPositionClassified">
        <link:definition>0000009 - Statement - Statement of Financial Position, Classified</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="BusinessDescriptionandBasisofPresentation" roleURI="http://www.mt.com/role/BusinessDescriptionandBasisofPresentation">
        <link:definition>0000010 - Disclosure - Business Description and Basis of Presentation</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SummaryofSignificantAccountingPolicies" roleURI="http://www.mt.com/role/SummaryofSignificantAccountingPolicies">
        <link:definition>0000011 - Disclosure - Summary of Significant Accounting Policies</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RevenuefromContractswithCustomers" roleURI="http://www.mt.com/role/RevenuefromContractswithCustomers">
        <link:definition>0000012 - Disclosure - Revenue from Contracts with Customers</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Acquisitions" roleURI="http://www.mt.com/role/Acquisitions">
        <link:definition>0000013 - Disclosure - Acquisitions</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Inventories" roleURI="http://www.mt.com/role/Inventories">
        <link:definition>0000014 - Disclosure - Inventories</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FinancialInstruments" roleURI="http://www.mt.com/role/FinancialInstruments">
        <link:definition>0000015 - Disclosure - Financial Instruments</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FairValueMeasurements" roleURI="http://www.mt.com/role/FairValueMeasurements">
        <link:definition>0000016 - Disclosure - Fair Value Measurements</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="PropertyPlantandEquipmentNet" roleURI="http://www.mt.com/role/PropertyPlantandEquipmentNet">
        <link:definition>0000017 - Disclosure - Property, Plant and Equipment, Net</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="GoodwillandOtherIntangibleAssets" roleURI="http://www.mt.com/role/GoodwillandOtherIntangibleAssets">
        <link:definition>0000018 - Disclosure - Goodwill and Other Intangible Assets</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Debt" roleURI="http://www.mt.com/role/Debt">
        <link:definition>0000019 - Disclosure - Debt</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ShareholdersEquity" roleURI="http://www.mt.com/role/ShareholdersEquity">
        <link:definition>0000020 - Disclosure - Shareholders' Equity</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="EquityIncentivePlan" roleURI="http://www.mt.com/role/EquityIncentivePlan">
        <link:definition>0000021 - Disclosure - Equity Incentive Plan</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="BenefitPlans" roleURI="http://www.mt.com/role/BenefitPlans">
        <link:definition>0000022 - Disclosure - Benefit Plans</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Taxes" roleURI="http://www.mt.com/role/Taxes">
        <link:definition>0000023 - Disclosure - Taxes</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="OtherChargesIncomeNet" roleURI="http://www.mt.com/role/OtherChargesIncomeNet">
        <link:definition>0000024 - Disclosure - Other Charges (Income), Net</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Leases" roleURI="http://www.mt.com/role/Leases">
        <link:definition>0000025 - Disclosure - Leases</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CommitmentsandContingencies" roleURI="http://www.mt.com/role/CommitmentsandContingencies">
        <link:definition>0000026 - Disclosure - Commitments and Contingencies</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SegmentReporting" roleURI="http://www.mt.com/role/SegmentReporting">
        <link:definition>0000027 - Disclosure - Segment Reporting</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SummaryofSignificantAccountingPoliciesPolicies" roleURI="http://www.mt.com/role/SummaryofSignificantAccountingPoliciesPolicies">
        <link:definition>0000028 - Disclosure - Summary of Significant Accounting Policies (Policies)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RevenuefromContractswithCustomersTables" roleURI="http://www.mt.com/role/RevenuefromContractswithCustomersTables">
        <link:definition>0000029 - Disclosure - Revenue from Contracts with Customers (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="AcquisitionsTables" roleURI="http://www.mt.com/role/AcquisitionsTables">
        <link:definition>0000030 - Disclosure - Acquisitions (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="InventoriesTables" roleURI="http://www.mt.com/role/InventoriesTables">
        <link:definition>0000031 - Disclosure - Inventories (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FairValueMeasurementsTables" roleURI="http://www.mt.com/role/FairValueMeasurementsTables">
        <link:definition>0000032 - Disclosure - Fair Value Measurements (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="PropertyPlantandEquipmentNetTables" roleURI="http://www.mt.com/role/PropertyPlantandEquipmentNetTables">
        <link:definition>0000033 - Disclosure - Property, Plant and Equipment, Net (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="GoodwillandOtherIntangibleAssetsTables" roleURI="http://www.mt.com/role/GoodwillandOtherIntangibleAssetsTables">
        <link:definition>0000034 - Disclosure - Goodwill and Other Intangible Assets (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DebtTables" roleURI="http://www.mt.com/role/DebtTables">
        <link:definition>0000035 - Disclosure - Debt (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ShareholdersEquityTables" roleURI="http://www.mt.com/role/ShareholdersEquityTables">
        <link:definition>0000036 - Disclosure - Shareholders' Equity (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="EquityIncentivePlanTables" roleURI="http://www.mt.com/role/EquityIncentivePlanTables">
        <link:definition>0000037 - Disclosure - Equity Incentive Plan (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="BenefitPlansTables" roleURI="http://www.mt.com/role/BenefitPlansTables">
        <link:definition>0000038 - Disclosure - Benefit Plans (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="TaxesTables" roleURI="http://www.mt.com/role/TaxesTables">
        <link:definition>0000039 - Disclosure - Taxes (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LeasesTables" roleURI="http://www.mt.com/role/LeasesTables">
        <link:definition>0000040 - Disclosure - Leases (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SegmentReportingTables" roleURI="http://www.mt.com/role/SegmentReportingTables">
        <link:definition>0000041 - Disclosure - Segment Reporting (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SummaryofSignificantAccountingPoliciesTables" roleURI="http://www.mt.com/role/SummaryofSignificantAccountingPoliciesTables">
        <link:definition>0000042 - Disclosure - Summary of Significant Accounting Policies (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SummaryofSignificantAccountingPolicies2Details" roleURI="http://www.mt.com/role/SummaryofSignificantAccountingPolicies2Details">
        <link:definition>0000043 - Disclosure - Summary of Significant Accounting Policies 2 (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RevenuefromContractswithCustomersDetails" roleURI="http://www.mt.com/role/RevenuefromContractswithCustomersDetails">
        <link:definition>0000044 - Disclosure - Revenue from Contracts with Customers (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="AcquisitionsBusinessCombinationsDetails" roleURI="http://www.mt.com/role/AcquisitionsBusinessCombinationsDetails">
        <link:definition>0000045 - Disclosure - Acquisitions Business Combinations (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="InventoriesDetails" roleURI="http://www.mt.com/role/InventoriesDetails">
        <link:definition>0000046 - Disclosure - Inventories (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FinancialInstrumentsDetails" roleURI="http://www.mt.com/role/FinancialInstrumentsDetails">
        <link:definition>0000047 - Disclosure - Financial Instruments (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FairValueMeasurementsDetails" roleURI="http://www.mt.com/role/FairValueMeasurementsDetails">
        <link:definition>0000048 - Disclosure - Fair Value Measurements (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="PropertyPlantandEquipmentNetDetails" roleURI="http://www.mt.com/role/PropertyPlantandEquipmentNetDetails">
        <link:definition>0000049 - Disclosure - Property, Plant and Equipment, Net (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="GoodwillandOtherIntangibleAssetsDetails" roleURI="http://www.mt.com/role/GoodwillandOtherIntangibleAssetsDetails">
        <link:definition>0000050 - Disclosure - Goodwill and Other Intangible Assets (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="GoodwillandOtherIntangibleAssets1Details" roleURI="http://www.mt.com/role/GoodwillandOtherIntangibleAssets1Details">
        <link:definition>0000051 - Disclosure - Goodwill and Other Intangible Assets 1 (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="GoodwillandOtherIntangibleAssetsNarrativeDetails" roleURI="http://www.mt.com/role/GoodwillandOtherIntangibleAssetsNarrativeDetails">
        <link:definition>0000052 - Disclosure - Goodwill and Other Intangible Assets Narrative (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DebtScheduleofDebtDetails" roleURI="http://www.mt.com/role/DebtScheduleofDebtDetails">
        <link:definition>0000053 - Disclosure - Debt - Schedule of Debt (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DebtNarrativeDetails" roleURI="http://www.mt.com/role/DebtNarrativeDetails">
        <link:definition>0000054 - Disclosure - Debt - Narrative (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ShareholdersEquityOtherComprehensiveIncomeRollforwardDetails" roleURI="http://www.mt.com/role/ShareholdersEquityOtherComprehensiveIncomeRollforwardDetails">
        <link:definition>0000055 - Disclosure - Shareholders' Equity Other Comprehensive Income Rollforward (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ShareholdersEquityAmountsrecognizedfromaccumulatedothercomprehensiveincomeDetails" roleURI="http://www.mt.com/role/ShareholdersEquityAmountsrecognizedfromaccumulatedothercomprehensiveincomeDetails">
        <link:definition>0000056 - Disclosure - Shareholders' Equity Amounts recognized from accumulated other comprehensive income (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ShareholdersEquityNarrativeDetails" roleURI="http://www.mt.com/role/ShareholdersEquityNarrativeDetails">
        <link:definition>0000057 - Disclosure - Shareholders' Equity Narrative (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="EquityIncentivePlanRollforwardofStockOptionsDetails" roleURI="http://www.mt.com/role/EquityIncentivePlanRollforwardofStockOptionsDetails">
        <link:definition>0000058 - Disclosure - Equity Incentive Plan Rollforward of Stock Options (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="EquityIncentivePlanWeightedAverageRemainingContractualLifeDetails" roleURI="http://www.mt.com/role/EquityIncentivePlanWeightedAverageRemainingContractualLifeDetails">
        <link:definition>0000059 - Disclosure - Equity Incentive Plan Weighted Average Remaining Contractual Life (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="EquityIncentivePlanWeightedAverageGrantDateFairValueDetails" roleURI="http://www.mt.com/role/EquityIncentivePlanWeightedAverageGrantDateFairValueDetails">
        <link:definition>0000060 - Disclosure - Equity Incentive Plan Weighted Average Grant Date Fair Value (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="EquityIncentivePlanRSUsandPSUsRollforwardDetails" roleURI="http://www.mt.com/role/EquityIncentivePlanRSUsandPSUsRollforwardDetails">
        <link:definition>0000061 - Disclosure - Equity Incentive Plan RSUs and PSUs Rollforward (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="EquityIncentivePlanNarrativeDetails" roleURI="http://www.mt.com/role/EquityIncentivePlanNarrativeDetails">
        <link:definition>0000062 - Disclosure - Equity Incentive Plan Narrative (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="BenefitPlansChangeinBenefitBenefitObligationandPlanAssetsDetails" roleURI="http://www.mt.com/role/BenefitPlansChangeinBenefitBenefitObligationandPlanAssetsDetails">
        <link:definition>0000063 - Disclosure - Benefit Plans Change in Benefit Benefit Obligation and Plan Assets (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="BenefitPlansAmountsRecognizedintheBalanceSheetDetails" roleURI="http://www.mt.com/role/BenefitPlansAmountsRecognizedintheBalanceSheetDetails">
        <link:definition>0000064 - Disclosure - Benefit Plans Amounts Recognized in the Balance Sheet (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="BenefitPlansTotalAmountsRecognizedinOCIDetails" roleURI="http://www.mt.com/role/BenefitPlansTotalAmountsRecognizedinOCIDetails">
        <link:definition>0000065 - Disclosure - Benefit Plans Total Amounts Recognized in OCI (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="BenefitPlansAmountsRecognizedinOtherComprehensiveIncomeDetails" roleURI="http://www.mt.com/role/BenefitPlansAmountsRecognizedinOtherComprehensiveIncomeDetails">
        <link:definition>0000066 - Disclosure - Benefit Plans Amounts Recognized in Other Comprehensive Income (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="BenefitPlansWeightedAverageRatesforPBODetails" roleURI="http://www.mt.com/role/BenefitPlansWeightedAverageRatesforPBODetails">
        <link:definition>0000067 - Disclosure - Benefit Plans Weighted Average Rates for PBO (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="BenefitPlansWeightedAverageRatesforNPPCDetails" roleURI="http://www.mt.com/role/BenefitPlansWeightedAverageRatesforNPPCDetails">
        <link:definition>0000068 - Disclosure - Benefit Plans Weighted Average Rates for NPPC (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="BenefitPlansNetPeriodicPensionCostsDetails" roleURI="http://www.mt.com/role/BenefitPlansNetPeriodicPensionCostsDetails">
        <link:definition>0000069 - Disclosure - Benefit Plans Net Periodic Pension Costs (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="BenefitPlansPensionFairValueAssetsDetails" roleURI="http://www.mt.com/role/BenefitPlansPensionFairValueAssetsDetails">
        <link:definition>0000070 - Disclosure - Benefit Plans Pension Fair Value Assets (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="BenefitPlansLevel3RollforwardDetails" roleURI="http://www.mt.com/role/BenefitPlansLevel3RollforwardDetails">
        <link:definition>0000071 - Disclosure - Benefit Plans Level 3 Rollforward (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="BenefitPlansFutureCashFlowsDetails" roleURI="http://www.mt.com/role/BenefitPlansFutureCashFlowsDetails">
        <link:definition>0000072 - Disclosure - Benefit Plans Future Cash Flows (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="BenefitPlansNarrativeDetails" roleURI="http://www.mt.com/role/BenefitPlansNarrativeDetails">
        <link:definition>0000073 - Disclosure - Benefit Plans Narrative (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="TaxesSummaryofEarningsDetails" roleURI="http://www.mt.com/role/TaxesSummaryofEarningsDetails">
        <link:definition>0000074 - Disclosure - Taxes Summary of Earnings (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="TaxesSummaryoftheprovisionfortaxesDetails" roleURI="http://www.mt.com/role/TaxesSummaryoftheprovisionfortaxesDetails">
        <link:definition>0000075 - Disclosure - Taxes Summary of the provision for taxes (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="TaxesEffectiveTaxRateReconciliationDetails" roleURI="http://www.mt.com/role/TaxesEffectiveTaxRateReconciliationDetails">
        <link:definition>0000076 - Disclosure - Taxes Effective Tax Rate Reconciliation (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="TaxesTaxEffectsofTemporaryDifferencesDetails" roleURI="http://www.mt.com/role/TaxesTaxEffectsofTemporaryDifferencesDetails">
        <link:definition>0000077 - Disclosure - Taxes Tax Effects of Temporary Differences (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="TaxesTaxEffectsofTemporaryDifferencesDetails_1" roleURI="http://www.mt.com/role/TaxesTaxEffectsofTemporaryDifferencesDetails_1">
        <link:definition>0000077 - Disclosure - Taxes Tax Effects of Temporary Differences (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="TaxesReconciliationofunrecognizedtaxbenefitsDetails" roleURI="http://www.mt.com/role/TaxesReconciliationofunrecognizedtaxbenefitsDetails">
        <link:definition>0000078 - Disclosure - Taxes Reconciliation of unrecognized tax benefits (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="TaxesNarrativeDetails" roleURI="http://www.mt.com/role/TaxesNarrativeDetails">
        <link:definition>0000079 - Disclosure - Taxes Narrative (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="OtherChargesIncomeNetOtherChargesIncomeNetDetails" roleURI="http://www.mt.com/role/OtherChargesIncomeNetOtherChargesIncomeNetDetails">
        <link:definition>0000080 - Disclosure - Other Charges (Income), Net Other Charges (Income), Net (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LeasesLeaseBalanceSheetDetails" roleURI="http://www.mt.com/role/LeasesLeaseBalanceSheetDetails">
        <link:definition>0000081 - Disclosure - Leases Lease Balance Sheet (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LeasesLeaseIncomeStatementDetails" roleURI="http://www.mt.com/role/LeasesLeaseIncomeStatementDetails">
        <link:definition>0000082 - Disclosure - Leases Lease Income Statement (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LeasesLeaseMaturityAnalysisDetails" roleURI="http://www.mt.com/role/LeasesLeaseMaturityAnalysisDetails">
        <link:definition>0000083 - Disclosure - Leases Lease Maturity Analysis (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LeasesLeaseNarrativeDetails" roleURI="http://www.mt.com/role/LeasesLeaseNarrativeDetails">
        <link:definition>0000084 - Disclosure - Leases Lease Narrative (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SegmentReportingSegmentDetails" roleURI="http://www.mt.com/role/SegmentReportingSegmentDetails">
        <link:definition>0000085 - Disclosure - Segment Reporting Segment (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SegmentReportingReconciliationofEarningsBeforeTaxesDetails" roleURI="http://www.mt.com/role/SegmentReportingReconciliationofEarningsBeforeTaxesDetails">
        <link:definition>0000086 - Disclosure - Segment Reporting Reconciliation of Earnings Before Taxes (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SegmentReportingRevenuesbyDivisionDetails" roleURI="http://www.mt.com/role/SegmentReportingRevenuesbyDivisionDetails">
        <link:definition>0000087 - Disclosure - Segment Reporting Revenues by Division (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SegmentReportingSalesandPPEbyDestinationDetails" roleURI="http://www.mt.com/role/SegmentReportingSalesandPPEbyDestinationDetails">
        <link:definition>0000088 - Disclosure - Segment Reporting Sales and PPE by Destination (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SegmentReportingTextualsDetails" roleURI="http://www.mt.com/role/SegmentReportingTextualsDetails">
        <link:definition>0000089 - Disclosure - Segment Reporting Textuals (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ScheduleIIValuationandQualifyingAccountsScheduleIIDetails" roleURI="http://www.mt.com/role/ScheduleIIValuationandQualifyingAccountsScheduleIIDetails">
        <link:definition>0000090 - Disclosure - Schedule II Valuation and Qualifying Accounts Schedule II (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
    </xs:appinfo>
  </xs:annotation>
  <xs:element id="mtd_February2019CrossCurrencySwapMember" abstract="true" name="February2019CrossCurrencySwapMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_DefinedBenefitPlanChangesInOciArisingDuringPeriod" abstract="false" name="DefinedBenefitPlanChangesInOciArisingDuringPeriod" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_CrossCurrencySwapMember" abstract="true" name="CrossCurrencySwapMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_GoodwillAndOtherIntangibleAssetsTextualsAbstract" abstract="true" name="GoodwillAndOtherIntangibleAssetsTextualsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="mtd_IndustrialproductsandservicesMember" abstract="true" name="IndustrialproductsandservicesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_A450010000RangeOfExercisePriceMember" abstract="true" name="A450010000RangeOfExercisePriceMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_A4.10SeniorNotesMember" abstract="true" name="A4.10SeniorNotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_NetSales" abstract="false" name="NetSales" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_TradenameIndefiniteLifeMember" abstract="true" name="TradenameIndefiniteLifeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_EliminationsAndCorporateSegmentMember" abstract="true" name="EliminationsAndCorporateSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_ScaleUpSystemsAcquisitionMember" abstract="true" name="ScaleUpSystemsAcquisitionMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_Deferredtaxbenefitprovisionexcludingdiscretetaxitems" abstract="false" name="Deferredtaxbenefitprovisionexcludingdiscretetaxitems" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_Customerprepaymentsanddeferredrevenue" abstract="false" name="Customerprepaymentsanddeferredrevenue" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_SharesRepurchasedUnderShareRepurchaseProgram" abstract="false" name="SharesRepurchasedUnderShareRepurchaseProgram" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="mtd_DefinedBenefitPlanAssumptionsUsedCalculatingProjectedBenefitObligationExpectedLongTermReturnOnAssets" abstract="false" name="DefinedBenefitPlanAssumptionsUsedCalculatingProjectedBenefitObligationExpectedLongTermReturnOnAssets" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="mtd_HealthcareCostTrendRateMinimumPercentage" abstract="false" name="HealthcareCostTrendRateMinimumPercentage" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="mtd_AmortizationofActuarialGainsLossesandPlanAmendments" abstract="false" name="AmortizationofActuarialGainsLossesandPlanAmendments" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_SwissPensionLoansMember" abstract="true" name="SwissPensionLoansMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_ShareBasedCompensationPerformanceSharesVestedInThePeriodForVestingOf2017PUs" abstract="false" name="ShareBasedCompensationPerformanceSharesVestedInThePeriodForVestingOf2017PUs" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="mtd_ValuationAllowanceSwissTaxReform" abstract="false" name="ValuationAllowanceSwissTaxReform" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_RevenueTransactionsWithOtherOperatingSegments" abstract="false" name="RevenueTransactionsWithOtherOperatingSegments" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_RealAssetMutualFundsCommoditiesDomain" abstract="true" name="RealAssetMutualFundsCommoditiesDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_CrossCurrencySwapinterestportionrecognizedinincome" abstract="false" name="CrossCurrencySwapinterestportionrecognizedinincome" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_RestOfWorldMember" abstract="true" name="RestOfWorldMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_ForwardCurrencyForwardContract" abstract="false" name="ForwardCurrencyForwardContract" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_USPensionBenefitsMember" abstract="true" name="USPensionBenefitsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_LineOfCreditFacilityForecastedBorrowingAmount" abstract="false" name="LineOfCreditFacilityForecastedBorrowingAmount" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_DocumentAndEntityInformationAbstract" abstract="true" name="DocumentAndEntityInformationAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="mtd_OtherOperationsMember" abstract="true" name="OtherOperationsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_PurchasedIntangiblesNetOfTax" abstract="false" name="PurchasedIntangiblesNetOfTax" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_ScheduleOfFiniteLivedAndIndefiniteLivedIntangibleAssetsByMajorClassTableTextBlock" abstract="false" name="ScheduleOfFiniteLivedAndIndefiniteLivedIntangibleAssetsByMajorClassTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="mtd_A545PercentSeniorNotesMember" abstract="true" name="A545PercentSeniorNotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_WeightedAverageExercisePriceAbstract" abstract="true" name="WeightedAverageExercisePriceAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="mtd_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansNetPlanAmendmentsAndPriorServiceCostsArisingDuringPeriodNetOfTax" abstract="false" name="OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansNetPlanAmendmentsAndPriorServiceCostsArisingDuringPeriodNetOfTax" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_PerformanceShareunitsNonvestedIntrinsicValue" abstract="false" name="PerformanceShareunitsNonvestedIntrinsicValue" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="mtd_BusinessCombinationContingentConsiderationOtherLiability" abstract="false" name="BusinessCombinationContingentConsiderationOtherLiability" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_June20213YRCrossCurrencySwapMember" abstract="true" name="June20213YRCrossCurrencySwapMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_SwissTaxReformnoncashdeferredtaxbenefit" abstract="false" name="SwissTaxReformnoncashdeferredtaxbenefit" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_ConsolidatedBalanceSheetsAbstract" abstract="true" name="ConsolidatedBalanceSheetsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="mtd_ScheduleOfAssumptionsUsedInComputingBenefitObligationTableTextBlock" abstract="false" name="ScheduleOfAssumptionsUsedInComputingBenefitObligationTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="mtd_UsOperationsSegmentMember" abstract="true" name="UsOperationsSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_OtherEuropeMember" abstract="true" name="OtherEuropeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_A283SeniorNotesMember" abstract="true" name="A283SeniorNotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_ShareBasedCompensationPerformanceSharesVestedinthePeriod" abstract="false" name="ShareBasedCompensationPerformanceSharesVestedinthePeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="mtd_FixedIncomeMutualFundsInsuranceContractsDomain" abstract="true" name="FixedIncomeMutualFundsInsuranceContractsDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_FixedIncomeSecuritiesCorporateAndGovernmentBondsDomain" abstract="true" name="FixedIncomeSecuritiesCorporateAndGovernmentBondsDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_BalanceSheetAbstract" abstract="true" name="BalanceSheetAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="mtd_IntangibleAssetsAccumulatedAmortization" abstract="false" name="IntangibleAssetsAccumulatedAmortization" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_AggregateIntrinsicValueAbstract" abstract="true" name="AggregateIntrinsicValueAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="mtd_LesseeOperatingLeasesStatementofPositionlocationandbalancesTableTextBlock" abstract="false" name="LesseeOperatingLeasesStatementofPositionlocationandbalancesTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="mtd_SegmentProfitInformation" abstract="false" name="SegmentProfitInformation" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_A106EuroSeniorNotesMember" abstract="true" name="A106EuroSeniorNotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_SwissOperationsSegmentMember" abstract="true" name="SwissOperationsSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_A10045000RangeOfExercisePriceMember" abstract="true" name="A10045000RangeOfExercisePriceMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_ChangeinCarryingValueVerseFairValueofLongTermDebt" abstract="false" name="ChangeinCarryingValueVerseFairValueofLongTermDebt" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_TotalAsiaRestOfWorldMember" abstract="true" name="TotalAsiaRestOfWorldMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_June20194YRCrossCurrencySwapMember" abstract="true" name="June20194YRCrossCurrencySwapMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_SharesReservedForGrantForStockOptionPlan" abstract="false" name="SharesReservedForGrantForStockOptionPlan" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="mtd_ChineseOperationsSegmentMember" abstract="true" name="ChineseOperationsSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_DefinedBenefitPlanPurchasesTotal" abstract="false" name="DefinedBenefitPlanPurchasesTotal" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_FixedIncomeMutualFundsCoreBondDomain" abstract="true" name="FixedIncomeMutualFundsCoreBondDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_RetailproductsandservicesMember" abstract="true" name="RetailproductsandservicesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_FinancialInstrumentsAbstract" abstract="true" name="FinancialInstrumentsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="mtd_ScheduleOfAssumptionsUsedInComputingPensionCostTableTextBlock" abstract="false" name="ScheduleOfAssumptionsUsedInComputingPensionCostTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="mtd_OtherOperationsSegmentMember" abstract="true" name="OtherOperationsSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_FairValueMeasurementsAbstract" abstract="true" name="FairValueMeasurementsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="mtd_EffectiveTaxRateReconciliationExcessTaxBenefits" abstract="false" name="EffectiveTaxRateReconciliationExcessTaxBenefits" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_WesternEuropeanOperationsSegmentMember" abstract="true" name="WesternEuropeanOperationsSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_DeferredTaxLiabilitiesTaxDeferredExpenseCompensationandBenefitsPension" abstract="false" name="DeferredTaxLiabilitiesTaxDeferredExpenseCompensationandBenefitsPension" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_AmortizationOfActuarialGainsLossesAndPlanAmendmentsAndPriorServiceCost" abstract="false" name="AmortizationOfActuarialGainsLossesAndPlanAmendmentsAndPriorServiceCost" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_ProvenTechnologyAndPatentsMember" abstract="true" name="ProvenTechnologyAndPatentsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_DeferredTaxLiabilitiesRightofUseAssetandOtherAssets" abstract="false" name="DeferredTaxLiabilitiesRightofUseAssetandOtherAssets" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_ForeignCurrencyContractCurrentAssetFairValue" abstract="false" name="ForeignCurrencyContractCurrentAssetFairValue" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_DefinedBenefitPlansAmortizationOfGainsLossesAndOtherExpenses" abstract="false" name="DefinedBenefitPlansAmortizationOfGainsLossesAndOtherExpenses" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_IntangibleAssetsExcludingGoodwillGross" abstract="false" name="IntangibleAssetsExcludingGoodwillGross" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_TotalEuropeMember" abstract="true" name="TotalEuropeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_PendoTECHAcquisitionMember" abstract="true" name="PendoTECHAcquisitionMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_CapitalizedDevelopmentSoftwareCostsMember" abstract="true" name="CapitalizedDevelopmentSoftwareCostsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_USOperationsMember" abstract="true" name="USOperationsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_TradenameFiniteLifeMember" abstract="true" name="TradenameFiniteLifeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_TableofPerformanceShareUnitMonteCarloAssumptionsTableTextBlock" abstract="false" name="TableofPerformanceShareUnitMonteCarloAssumptionsTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="mtd_WesternEuropeanOperationsMember" abstract="true" name="WesternEuropeanOperationsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_EndCustomersMember" abstract="true" name="EndCustomersMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_OtherTypesOfInvestmentsGlobalAllocationFundsDomain" abstract="true" name="OtherTypesOfInvestmentsGlobalAllocationFundsDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_PerformanceShareUnitTotalGrantValue" abstract="false" name="PerformanceShareUnitTotalGrantValue" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_OtherTypesofInvestmentsInsurancelinkedsecuritiesMember" abstract="true" name="OtherTypesofInvestmentsInsurancelinkedsecuritiesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_ReconciliationOfOperatingProfitLossFromSegmentToConsolidated" abstract="false" name="ReconciliationOfOperatingProfitLossFromSegmentToConsolidated" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_PerformanceOptionFairValue" abstract="false" name="PerformanceOptionFairValue" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="mtd_DefinedBenefitPlanAssetsFairValueHierarchyMember" abstract="true" name="DefinedBenefitPlanAssetsFairValueHierarchyMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_ShareRepurchaseProgramAndTreasuryStockAbstract" abstract="true" name="ShareRepurchaseProgramAndTreasuryStockAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="mtd_ChineseOperationsMember" abstract="true" name="ChineseOperationsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_June20214YRCrossCurrencySwapMember" abstract="true" name="June20214YRCrossCurrencySwapMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_ExerciseOfStockOptionsAndRestrictedStockUnitsSharesTreasuryStockReissued" abstract="false" name="ExerciseOfStockOptionsAndRestrictedStockUnitsSharesTreasuryStockReissued" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="mtd_DefinedBenefitPlanChangesInOciArisingDuringPeriodNetOfTax" abstract="false" name="DefinedBenefitPlanChangesInOciArisingDuringPeriodNetOfTax" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_CAPEXRelatedToGovernmentGrant" abstract="false" name="CAPEXRelatedToGovernmentGrant" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_ImpactontaxraterelatedtoSwissTaxReform" abstract="false" name="ImpactontaxraterelatedtoSwissTaxReform" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="mtd_A281SeniorNoteMember" abstract="true" name="A281SeniorNoteMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_StockRepurchaseProgramAdditionalAuthorizedAmount" abstract="false" name="StockRepurchaseProgramAdditionalAuthorizedAmount" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_RestrictedStockUnitsVestingPeriod" abstract="false" name="RestrictedStockUnitsVestingPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="mtd_CompanyStockMember" abstract="true" name="CompanyStockMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_DeferredTaxAssetsOperatingLossAndTaxCreditCarryforward" abstract="false" name="DeferredTaxAssetsOperatingLossAndTaxCreditCarryforward" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_USFederalCorporateIncomeTaxRate" abstract="false" name="USFederalCorporateIncomeTaxRate" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="mtd_DeferredTaxLiabilityInventory" abstract="false" name="DeferredTaxLiabilityInventory" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_PerformanceShareUnitsVestingPeriod" abstract="false" name="PerformanceShareUnitsVestingPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="mtd_InventoriesAbstract" abstract="true" name="InventoriesAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="mtd_PerformanceStockUnitsGrantsinPeriod" abstract="false" name="PerformanceStockUnitsGrantsinPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="mtd_PerformanceSharePayoutPercentage" abstract="false" name="PerformanceSharePayoutPercentage" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="mtd_RepaymentsOfBorrowings" abstract="false" name="RepaymentsOfBorrowings" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_June20192YRCrossCurrencySwapMember" abstract="true" name="June20192YRCrossCurrencySwapMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_A4.24SeniorNotesMember" abstract="true" name="A4.24SeniorNotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_AuditorInformationAbstract" abstract="true" name="AuditorInformationAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="mtd_PensionAndOtherPostretirementBenefitPlansAccumulatedOtherComprehensiveIncomeLossNetGainsLossesAfterTax" abstract="false" name="PensionAndOtherPostretirementBenefitPlansAccumulatedOtherComprehensiveIncomeLossNetGainsLossesAfterTax" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_OtherAmericasMember" abstract="true" name="OtherAmericasMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_DefinedBenefitPlansImpactOfFxOnCurrentYearChangeInOciNetOfTax" abstract="false" name="DefinedBenefitPlansImpactOfFxOnCurrentYearChangeInOciNetOfTax" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_ImpactofAdoptingASU201707ASC715CompensationRetirementBenefit" abstract="false" name="ImpactofAdoptingASU201707ASC715CompensationRetirementBenefit" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_A367PercentSeniorNotesMember" abstract="true" name="A367PercentSeniorNotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_HealthcareCostTrendRateMaximum" abstract="false" name="HealthcareCostTrendRateMaximum" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="mtd_A291SeniorNoteMember" abstract="true" name="A291SeniorNoteMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_OtherTypesOfInvestmentsMultiStrategyFundMember" abstract="true" name="OtherTypesOfInvestmentsMultiStrategyFundMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_ShareRepurchaseProgramTotalCostProgramtoDate" abstract="false" name="ShareRepurchaseProgramTotalCostProgramtoDate" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_Swisstaxreformintangibleasset" abstract="false" name="Swisstaxreformintangibleasset" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_A3.84SeniorNotesMember" abstract="true" name="A3.84SeniorNotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_DefinedBenefitPlansServiceCostAndOther" abstract="false" name="DefinedBenefitPlansServiceCostAndOther" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_PerformanceShareUnitPayoutPercentageMinimum" abstract="false" name="PerformanceShareUnitPayoutPercentageMinimum" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="mtd_A3.91SeniorNotesMember" abstract="true" name="A3.91SeniorNotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_MaximumUsefulLives" abstract="false" name="MaximumUsefulLives" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="mtd_BusinessDescriptionAndBasisOfPresentationAbstract" abstract="true" name="BusinessDescriptionAndBasisOfPresentationAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="mtd_Cumulativegainlossinotherothercomprehensiveincomerelatedtothechangeinanetinvestmenthedge." abstract="false" name="Cumulativegainlossinotherothercomprehensiveincomerelatedtothechangeinanetinvestmenthedge." nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_AllocatedShareBasedCompensationExpenseForPSUs" abstract="false" name="AllocatedShareBasedCompensationExpenseForPSUs" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_A10000AndAboveRangeOfExercisePriceMember" abstract="true" name="A10000AndAboveRangeOfExercisePriceMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_USEquityMutualFundsMember" abstract="true" name="USEquityMutualFundsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_CrossCurrencyCashFlowHedgeGainLossReclassifiedtoEarningsNet" abstract="false" name="CrossCurrencyCashFlowHedgeGainLossReclassifiedtoEarningsNet" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_A2.25100MillionInterestRateSwapMember" abstract="true" name="A2.25100MillionInterestRateSwapMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_Changeinleaseliabilitycashflow" abstract="false" name="Changeinleaseliabilitycashflow" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_OtherComprehensiveIncomeLossAmortizationPensionAndOtherPostretirementBenefitPlansNetPriorServiceCostRecognizedInNetPeriodicBenefitCostAfterTax" abstract="false" name="OtherComprehensiveIncomeLossAmortizationPensionAndOtherPostretirementBenefitPlansNetPriorServiceCostRecognizedInNetPeriodicBenefitCostAfterTax" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_AllocatedShareBasedCompensationExpenseForRestrictedStockUnits" abstract="false" name="AllocatedShareBasedCompensationExpenseForRestrictedStockUnits" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_November20212YRCrossCurrencySwapMember" abstract="true" name="November20212YRCrossCurrencySwapMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_SummaryOfSignificantAccountingPoliciesAbstract" abstract="true" name="SummaryOfSignificantAccountingPoliciesAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="mtd_InternationalEquityMutualFundsDomain" abstract="true" name="InternationalEquityMutualFundsDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_ShortTermCrossCurrencySwapMember" abstract="true" name="ShortTermCrossCurrencySwapMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_UnrecognizedTaxBenefitsForeignCurrencyTranslationDecreasesIncreasesToPriorYearTaxPositions" abstract="false" name="UnrecognizedTaxBenefitsForeignCurrencyTranslationDecreasesIncreasesToPriorYearTaxPositions" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_ProceedsFromBorrowings" abstract="false" name="ProceedsFromBorrowings" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_DeferredTaxBenefitnetrelatedtoSwissTaxReform" abstract="false" name="DeferredTaxBenefitnetrelatedtoSwissTaxReform" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_A1.47EUROSeniorNotesMember" abstract="true" name="A1.47EUROSeniorNotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_LaboratoryproductsandservicesMember" abstract="true" name="LaboratoryproductsandservicesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_EmergingMarketsEquityMutualFundsDomain" abstract="true" name="EmergingMarketsEquityMutualFundsDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_ProceedsFromGovernmentFunding" abstract="false" name="ProceedsFromGovernmentFunding" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_ShortTermDebtAndLongTermDebtCurrentMaturities" abstract="false" name="ShortTermDebtAndLongTermDebtCurrentMaturities" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_A3.19SeniorNotesMember" abstract="true" name="A3.19SeniorNotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_PerformanceShareUnitNonvestedNumberofShares" abstract="false" name="PerformanceShareUnitNonvestedNumberofShares" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="mtd_PropertyPlantAndEquipmentUsefulLifeTableTextBlock" abstract="false" name="PropertyPlantAndEquipmentUsefulLifeTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="mtd_EmployeeTerminationBenefitsPolicyTextBlock" abstract="false" name="EmployeeTerminationBenefitsPolicyTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="mtd_GrossDeferredTaxAssetforSwissTaxReform" abstract="false" name="GrossDeferredTaxAssetforSwissTaxReform" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_TotalAmericasMember" abstract="true" name="TotalAmericasMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_A1.30EuroSeniorNotesMember" abstract="true" name="A1.30EuroSeniorNotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_RemainingProceedsRelatedToGovernmentGrant" abstract="false" name="RemainingProceedsRelatedToGovernmentGrant" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_PercentageofDisaggregatedRevenueinRelationshiptoSegments" abstract="false" name="PercentageofDisaggregatedRevenueinRelationshiptoSegments" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="mtd_SwissOperationsMember" abstract="true" name="SwissOperationsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_AmortizationOfAcquiredIntangibleAssetNetOfTax" abstract="false" name="AmortizationOfAcquiredIntangibleAssetNetOfTax" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_ConsolidatedStatementsOfOperationsAbstract" abstract="true" name="ConsolidatedStatementsOfOperationsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="mtd_BusinessCombinationContingentConsiderationLiabilityIncrease" abstract="false" name="BusinessCombinationContingentConsiderationLiabilityIncrease" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_CrossCurrencySwapRevaluationPortionRecognizedinEarnings" abstract="false" name="CrossCurrencySwapRevaluationPortionRecognizedinEarnings" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_LongTermDebtPercentageBearingFixedInterestPercentage" abstract="false" name="LongTermDebtPercentageBearingFixedInterestPercentage" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="mtd_ShareBasedCompensationPerformanceSharesForfeitedintheperiod" abstract="false" name="ShareBasedCompensationPerformanceSharesForfeitedintheperiod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="mtd_SwissPensionLoanslocalcurrency" abstract="false" name="SwissPensionLoanslocalcurrency" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_NonUSPensionBenefitsMember" abstract="true" name="NonUSPensionBenefitsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_DefinedBenefitPlansImpactOfFxOnCurrentYearChangeInOci" abstract="false" name="DefinedBenefitPlansImpactOfFxOnCurrentYearChangeInOci" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mtd_ConsolidatedStatementsOfCashFlowsAbstract" abstract="true" name="ConsolidatedStatementsOfCashFlowsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="mtd_OtherAcquisitionsMember" abstract="true" name="OtherAcquisitionsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mtd_PerformanceShareUnitsPayoutPercentageMaximum" abstract="false" name="PerformanceShareUnitsPayoutPercentageMaximum" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="mtd_MinimumUsefulLives" abstract="false" name="MinimumUsefulLives" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
</xs:schema>
