v3.3.1.900

Consolidated Statements of Operations and Comprehensive Loss - USD ($) shares in Thousands, $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2015 | Dec. 31, 2014 | Dec. 31, 2013
Revenues |  |  |
Product revenues | $ 188,168 | $ 157,308 | $ 54,955
Other revenues | 2,187 | 1,981 | 216
Total revenues | 190,355 | 159,289 | 55,171
Cost and expenses |  |  |
Cost of product revenues | 112,845 | 78,396 | 37,275
Research and development | 27,711 | 17,292 | 11,550
Selling, general and administrative | 109,637 | 62,936 | 31,614
Total cost and expenses | 250,193 | 158,624 | 80,439
Gain (loss) from operations | (59,838) | 665 | (25,268)
Interest Expense | (3,505) | (4,219) | (1,873)
Interest expense from accretion of convertible notes |  |  | (7,901)
Interest benefit (expense) from changes in the fair value of long term debt | 964 | 118 | (2,166)
Other (expense) income, net | (7,896) | (1,716) | 98
Net (loss) | (70,275) | (5,152) | (37,110)
Unrealized loss on available-for-sale securities, net of tax | (1,416) |  |
Comprehensive (loss) | $ (71,691) | $ (5,152) | $ (37,110)
Basic and diluted net loss per share (in dollars per share) | $ (2.68) | $ (1.07) | $ (9.66)
Weighted-average number of shares used in computing basic and diluted net loss per share: | 26,204 | 4,800 | 3,841

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