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v3.21.1

Summary of Significant Accounting Policies - Liquidity Matters (Details) - USD ($) $ / shares in Units, $ in Thousands | 1 Months Ended | 3 Months Ended |  |
--- | --- | --- | --- | ---
Sep. 30, 2020 | Apr. 30, 2020 | Oct. 31, 2019 | Apr. 30, 2019 | Mar. 31, 2021 | Mar. 31, 2020 | Dec. 31, 2020 | Dec. 31, 2019
Policies |  |  |  |  |  |  |  |
Net (loss) income |  |  |  |  | $ (63,853) | $ (35,372) |  |
Accumulated deficit |  |  |  |  | 986,973 |  | $ 929,318 |
Cash, cash equivalents and restricted cash |  |  |  |  | 65,289 | $ 74,199 | 48,855 | $ 61,981
Marketable securities |  |  |  |  | 588,446 |  | 688,606 |
Short-term Credit Line, outstanding balance |  |  |  |  | $ 50,052 |  | $ 50,054 |
Common stock, shares issued |  |  |  |  | 87,430,000 |  | 86,223,000 |
Convertible Notes |  |  |  |  |  |  |  |
Policies |  |  |  |  |  |  |  |
Outstanding principal balance |  | $ 287,500 |  |  | $ 287,500 |  |  |
Per annum interest rate (as a percent) |  | 2.25% |  |  | 2.25% |  |  |
Net proceeds |  | $ 278,300 |  |  |  |  |  |
Debt principal balance |  |  |  |  | $ 287,500 |  |  |
Equity offering |  |  |  |  |  |  |  |
Policies |  |  |  |  |  |  |  |
Common stock, shares issued | 4,791,665 |  | 6,571,428 | 6,052,631 |  |  |  |
Stock issued (in dollars per share) | $ 60.00 |  | $ 35 | $ 19 |  |  |  |
Payment of offering expenses | $ 300 |  | $ 400 | $ 600 |  |  |  |
Proceeds from issuance of common stock | $ 271,000 |  | $ 216,200 | $ 108,100 |  |  |  |

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