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v3.21.1

Condensed Consolidated Statements of Stockholders' Equity - USD ($) shares in Thousands, $ in Thousands | Common stock | Additional Paid-in Capital | Accumulated Other Comprehensive Income | Accumulated Deficit | Total
--- | --- | --- | --- | --- | ---
Balance at Dec. 31, 2019 | $ 8 | $ 976,955 | $ 919 | $ (699,171) | $ 278,711
Balance (in shares) at Dec. 31, 2019 | 78,005 |  |  |  |
Issuance of common stock upon exercise of stock options |  | 3,826 |  |  | 3,826
Issuance of common stock upon exercise of stock options (in shares) | 356 |  |  |  |
Vesting of restricted stock units (in shares) | 291 |  |  |  |
Stock based compensation |  | 7,418 |  |  | 7,418
Unrealized (loss) gain on available-for-sale securities |  |  | 4,747 |  | 4,747
Cumulative-effect adjustment upon adoption |  |  |  | (403) | (403)
Net loss |  |  |  | (35,372) | (35,372)
Balance at Mar. 31, 2020 | $ 8 | 988,199 | 5,666 | (734,946) | 258,927
Balance (in shares) at Mar. 31, 2020 | 78,652 |  |  |  |
Balance at Dec. 31, 2020 | $ 9 | 1,411,286 | 4,259 | (929,318) | $ 486,236
Balance (in shares) at Dec. 31, 2020 | 86,223 |  |  |  | 86,223
Issuance of common stock upon exercise of stock options |  | 4,570 |  |  | $ 4,570
Issuance of common stock upon exercise of stock options (in shares) | 575 |  |  |  |
Vesting of restricted stock units (in shares) | 632 |  |  |  |
Stock based compensation |  | 23,232 |  |  | 23,232
Unrealized (loss) gain on available-for-sale securities |  |  | (1,062) |  | (1,062)
Cumulative-effect adjustment upon adoption |  | (82,876) |  | 6,198 | (76,678)
Net loss |  |  |  | (63,853) | (63,853)
Balance at Mar. 31, 2021 | $ 9 | $ 1,356,212 | $ 3,197 | $ (986,973) | $ 372,445
Balance (in shares) at Mar. 31, 2021 | 87,430 |  |  |  | 87,430

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