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Leases (Details) $ in Thousands | 1 Months Ended | 3 Months Ended | 6 Months Ended |
--- | --- | --- | --- | ---
Sep. 30, 2021 USD ($) ft² | Jun. 30, 2022 USD ($) ft² | Jun. 30, 2021 USD ($) | Jun. 30, 2022 USD ($) ft² item lease | Jun. 30, 2021 USD ($) | Dec. 31, 2021 USD ($)
Lessee, Lease, Description [Line Items] |  |  |  |  |  |
Operating lease liabilities, current portion included in other accrued liabilities | $ |  | $ 5,636 |  | $ 5,636 |  | $ 5,752
Operating lease liabilities, long-term portion | $ |  | 65,417 |  | 65,417 |  | 61,036
Operating lease liabilities | $ |  | $ 71,053 |  | 71,053 |  | $ 66,788
Noncash investing activities related to right-of-use assets | $ |  |  |  | $ 7,500 | $ 30,100 |
Weighted average remaining lease term |  | 4 years 10 months 20 days |  | 4 years 10 months 20 days |  |
Weighted average discount rate (as a percent) |  | 6.20% |  | 6.20% |  |
Lease expense | $ |  | $ 3,300 | $ 2,700 | $ 6,500 | 5,400 |
Operating lease payments | $ |  | $ 2,800 | $ 2,500 | $ 5,528 | $ 4,992 |
Austin TX, Long-term Lease |  |  |  |  |  |
Lessee, Lease, Description [Line Items] |  |  |  |  |  |
Office space (area) |  | 94,000 |  | 94,000 |  |
Number of office space locations | lease |  |  |  | 2 |  |
Term of lease |  | 132 months |  | 132 months |  |
First Expansion Premises |  |  |  |  |  |
Lessee, Lease, Description [Line Items] |  |  |  |  |  |
Office space (area) |  | 32,500 |  | 32,500 |  |
Second Expansion Premises |  |  |  |  |  |
Lessee, Lease, Description [Line Items] |  |  |  |  |  |
Office space (area) |  | 65,222 |  | 65,222 |  |
Corporate Headquarters Lease |  |  |  |  |  |
Lessee, Lease, Description [Line Items] |  |  |  |  |  |
Office space (area) |  | 113,000 |  | 113,000 |  |
Number of office space locations | item |  |  |  | 2 |  |
Term of lease |  | 84 months |  | 84 months |  |
Renewal term of lease |  | 5 years |  | 5 years |  |
"First Space" Sublease |  |  |  |  |  |
Lessee, Lease, Description [Line Items] |  |  |  |  |  |
Number of office space locations |  |  |  | 88,000 |  |
"Second Space" Sublease |  |  |  |  |  |
Lessee, Lease, Description [Line Items] |  |  |  |  |  |
Number of office space locations |  |  |  | 25,000 |  |
Corporate Headquarters Lease Amendment |  |  |  |  |  |
Lessee, Lease, Description [Line Items] |  |  |  |  |  |
Annual lease payment | $ |  |  |  | $ 9,300 |  |
Term of lease |  | 48 months |  | 48 months |  |
Tukwila, WA Lease |  |  |  |  |  |
Lessee, Lease, Description [Line Items] |  |  |  |  |  |
Office space (area) |  | 10,000 |  | 10,000 |  |
Term of lease |  | 62 months |  | 62 months |  |
Renewal term of lease |  | 5 years |  | 5 years |  |
San Carlos, CA Sublease |  |  |  |  |  |
Lessee, Lease, Description [Line Items] |  |  |  |  |  |
Office space (area) |  | 25,879 |  | 25,879 |  |
Term of lease |  | 48 months |  | 48 months |  |
Sublease receivable | $ |  | $ 1,900 |  | $ 1,900 |  |
San Carlos, CA Sublease Amendment | Rentable square feet surrendered in lease amendment |  |  |  |  |  |
Lessee, Lease, Description [Line Items] |  |  |  |  |  |
Office space (area) |  | 25,879 |  | 25,879 |  |
South San Francisco, CA Lease |  |  |  |  |  |
Lessee, Lease, Description [Line Items] |  |  |  |  |  |
Office space (area) |  | 11,395 |  | 11,395 |  |
Annual lease payment | $ |  |  |  | $ 900 |  |
Term of lease |  | 36 months |  | 36 months |  |
Laboratory space in Canada |  |  |  |  |  |
Lessee, Lease, Description [Line Items] |  |  |  |  |  |
Office space (area) | 7,107 |  |  |  |  |
Annual lease payment | $ | $ 200 |  |  |  |  |
Term of lease | 24 months |  |  |  |  |

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