<SEC-DOCUMENT>0001697362-25-000009.txt : 20251029
<SEC-HEADER>0001697362-25-000009.hdr.sgml : 20251029
<ACCEPTANCE-DATETIME>20251029213505
ACCESSION NUMBER:		0001697362-25-000009
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20251027
FILED AS OF DATE:		20251029
DATE AS OF CHANGE:		20251029

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Brophy Michael Burkes
		CENTRAL INDEX KEY:			0001697362
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37478
		FILM NUMBER:		251431871

	MAIL ADDRESS:	
		STREET 1:		13011 MCCALLEN PASS
		STREET 2:		BUILDING A, SUITE 100
		CITY:			AUSTIN
		STATE:			TX
		ZIP:			78753

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Natera, Inc.
		CENTRAL INDEX KEY:			0001604821
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-MEDICAL LABORATORIES [8071]
		ORGANIZATION NAME:           	08 Industrial Applications and Services
		EIN:				010894487
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		13011 MCCALLEN PASS
		STREET 2:		BUILDING A SUITE 100
		CITY:			AUSTIN
		STATE:			TX
		ZIP:			78753
		BUSINESS PHONE:		650-249-9090

	MAIL ADDRESS:	
		STREET 1:		13011 MCCALLEN PASS
		STREET 2:		BUILDING A SUITE 100
		CITY:			AUSTIN
		STATE:			TX
		ZIP:			78753
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
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        <issuerName>Natera, Inc.</issuerName>
        <issuerTradingSymbol>NTRA</issuerTradingSymbol>
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            <rptOwnerName>Brophy Michael Burkes</rptOwnerName>
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            <rptOwnerCity>AUSTIN</rptOwnerCity>
            <rptOwnerState>TX</rptOwnerState>
            <rptOwnerZipCode>78753</rptOwnerZipCode>
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            <isTenPercentOwner>false</isTenPercentOwner>
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            <officerTitle>CHIEF FINANCIAL OFFICER</officerTitle>
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    <derivativeTable></derivativeTable>

    <footnotes>
        <footnote id="F1">The sale of shares was effected in order to satisfy tax withholding and remittance obligations in connection with the vesting of RSUs and made pursuant to a written instruction that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c) under the Exchange Act contained in the Reporting Person's Stock Unit Agreement granted on January 26, 2024.</footnote>
        <footnote id="F2">The sale of shares was effected in order to satisfy tax withholding and remittance obligations in connection with the vesting of RSUs and made pursuant to a written instruction that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c) under the Exchange Act contained in the Reporting Person's Stock Unit Agreement granted on January 27, 2023.</footnote>
        <footnote id="F3">The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 14, 2024.</footnote>
        <footnote id="F4">The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $189.49 to 190.26 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.</footnote>
        <footnote id="F5">The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $190.88 to $191.80 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.</footnote>
        <footnote id="F6">The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $191.93 to $192.46 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.</footnote>
        <footnote id="F7">The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $188.06 to $189.00 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.</footnote>
        <footnote id="F8">The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $189.24 to $190.05 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.</footnote>
        <footnote id="F9">The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $190.42 to $191.41 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.</footnote>
        <footnote id="F10">The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $191.98 to $192.29 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Vincent Fontanilla, Attorney-in-Fact</signatureName>
        <signatureDate>2025-10-29</signatureDate>
    </ownerSignature>
</ownershipDocument>
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</SEC-DOCUMENT>
