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Income Taxes - Reconciliation of Income Tax Expense (Benefit) at Statutory Federal Tax Rate (Details)
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Income Tax Disclosure [Abstract]      
U.S. statutory rate 21.00% 21.00% 21.00%
Foreign rate differential 0.60% 13.20% 4.80%
State taxes, net of federal benefit 2.40% (5.00%) (9.50%)
Federal and state R&D credits (5.90%) (49.40%) (26.20%)
Stock-based compensation (3.20%) (94.80%) (117.00%)
Extinguishment of debt 0.00% 0.00% (57.50%)
Capital loss carryforward expirations 0.00% 0.00% 52.10%
Non-deductible officers’ compensation 1.30% 52.40% 45.70%
Permanent items 0.70% 6.30% 1.90%
Foreign income taxed in the U.S. 0.70% 14.50% 0.00%
Change in valuation allowance (10.80%) 124.40% 97.90%
Tax rate changes 0.50% (30.90%) 0.00%
Change to prior year R&D credit (2.80%) 0.00% 0.00%
Intercompany transfer of intellectual property 0.00% 0.00% 4.60%
Other (0.60%) 1.70% 0.40%
Effective tax rate 3.90% 53.40% 18.20%