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Fair Value Measurements and Financial Instruments - Schedule of Fair Value Hierarchy (Details) - USD ($) |  | 12 Months Ended |
--- | --- | --- | ---
Jun. 02, 2021 | Dec. 31, 2021 | Dec. 31, 2020
Assets: |  |  |
Marketable securities |  | $ 581,872,000 | $ 983,279,000
Available for sale debt securities |  | 66,000,000 | 69,984,000
Equity securities |  | 269,800,000 | 298,689,000
Available for sale debt securities |  | 204,400,000 | 163,016,000
MorphoSys | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |
Assets: |  |  |
Maximum commitment to fund collaborative arrangement | $ 150,000,000 | 150,000,000 |
Forwards |  |  |
Assets: |  |  |
Available for sale debt securities |  | 0 | 0
Available for sale debt securities |  | 12,300,000 | 18,600,000
Fair Value, Recurring |  |  |
Assets: |  |  |
Available for sale debt securities |  | 66,000,000 | 69,984,000
Total current assets |  | 1,301,076,000 | 1,229,243,000
Equity securities |  | 269,800,000 | 298,689,000
Available for sale debt securities |  | 187,700,000 | 144,416,000
Total non-current assets |  | 474,200,000 | 467,144,000
Fair Value, Recurring | Corporate Debt Securities |  |  |
Assets: |  |  |
Marketable securities |  | 0 | 32,754,000
Fair Value, Recurring | Commercial Paper |  |  |
Assets: |  |  |
Marketable securities |  | 207,457,000 | 444,554,000
Fair Value, Recurring | Certificates of Deposit |  |  |
Assets: |  |  |
Marketable securities |  | 374,415,000 | 505,971,000
Fair Value, Recurring | Forwards |  |  |
Assets: |  |  |
Derivatives |  | 16,700,000 | 18,600,000
Fair Value, Recurring | Warrant |  |  |
Assets: |  |  |
Derivatives |  | 0 | 5,439,000
Level 1 | Fair Value, Recurring |  |  |
Assets: |  |  |
Available for sale debt securities |  | 0 | 0
Total current assets |  | 598,253,000 | 24,302,000
Equity securities |  | 226,787,000 | 298,689,000
Available for sale debt securities |  | 0 | 0
Total non-current assets |  | 226,787,000 | 298,689,000
Level 1 | Fair Value, Recurring | Corporate Debt Securities |  |  |
Assets: |  |  |
Marketable securities |  | 0 | 0
Level 1 | Fair Value, Recurring | Commercial Paper |  |  |
Assets: |  |  |
Marketable securities |  | 0 | 0
Level 1 | Fair Value, Recurring | Certificates of Deposit |  |  |
Assets: |  |  |
Marketable securities |  | 0 | 0
Level 1 | Fair Value, Recurring | Forwards |  |  |
Assets: |  |  |
Derivatives |  | 0 | 0
Level 1 | Fair Value, Recurring | Warrant |  |  |
Assets: |  |  |
Derivatives |  | 0 | 0
Level 1 | Fair Value, Recurring | Interest Rate Swap |  |  |
Assets: |  |  |
Derivative financial instruments |  | 0 | 5,400,000
Level 2 | Fair Value, Recurring |  |  |
Assets: |  |  |
Available for sale debt securities |  | 0 | 0
Total current assets |  | 636,823,000 | 1,134,957,000
Equity securities |  | 0 | 0
Available for sale debt securities |  | 0 | 0
Total non-current assets |  | 0 | 5,439,000
Level 2 | Fair Value, Recurring | Corporate Debt Securities |  |  |
Assets: |  |  |
Marketable securities |  | 0 | 32,754,000
Level 2 | Fair Value, Recurring | Commercial Paper |  |  |
Assets: |  |  |
Marketable securities |  | 207,457,000 | 444,554,000
Level 2 | Fair Value, Recurring | Certificates of Deposit |  |  |
Assets: |  |  |
Marketable securities |  | 374,415,000 | 505,971,000
Level 2 | Fair Value, Recurring | Forwards |  |  |
Assets: |  |  |
Derivatives |  | 0 | 0
Level 2 | Fair Value, Recurring | Warrant |  |  |
Assets: |  |  |
Derivatives |  | 0 | 5,439,000
Level 3 | Fair Value, Recurring |  |  |
Assets: |  |  |
Available for sale debt securities |  | 66,000,000 | 69,984,000
Total current assets |  | 66,000,000 | 69,984,000
Equity securities |  | 43,013,000 | 0
Available for sale debt securities |  | 187,700,000 | 144,416,000
Total non-current assets |  | 247,413,000 | 163,016,000
Level 3 | Fair Value, Recurring | Corporate Debt Securities |  |  |
Assets: |  |  |
Marketable securities |  | 0 | 0
Level 3 | Fair Value, Recurring | Commercial Paper |  |  |
Assets: |  |  |
Marketable securities |  | 0 | 0
Level 3 | Fair Value, Recurring | Certificates of Deposit |  |  |
Assets: |  |  |
Marketable securities |  | 0 | 0
Level 3 | Fair Value, Recurring | Forwards |  |  |
Assets: |  |  |
Derivatives |  | 16,700,000 | 18,600,000
Level 3 | Fair Value, Recurring | Warrant |  |  |
Assets: |  |  |
Derivatives |  | 0 | 0
Money Market Funds | Fair Value, Recurring |  |  |
Assets: |  |  |
Cash equivalents |  | 598,253,000 | 24,302,000
Money Market Funds | Level 1 | Fair Value, Recurring |  |  |
Assets: |  |  |
Cash equivalents |  | 598,253,000 | 24,302,000
Money Market Funds | Level 2 | Fair Value, Recurring |  |  |
Assets: |  |  |
Cash equivalents |  | 0 | 0
Money Market Funds | Level 3 | Fair Value, Recurring |  |  |
Assets: |  |  |
Cash equivalents |  | 0 | 0
Commercial Paper | Fair Value, Recurring |  |  |
Assets: |  |  |
Cash equivalents |  | 13,997,000 | 77,176,000
Commercial Paper | Level 1 | Fair Value, Recurring |  |  |
Assets: |  |  |
Cash equivalents |  | 0 | 0
Commercial Paper | Level 2 | Fair Value, Recurring |  |  |
Assets: |  |  |
Cash equivalents |  | 13,997,000 | 77,176,000
Commercial Paper | Level 3 | Fair Value, Recurring |  |  |
Assets: |  |  |
Cash equivalents |  | 0 | 0
Certificates of Deposit | Fair Value, Recurring |  |  |
Assets: |  |  |
Cash equivalents |  | 40,954,000 | 74,502,000
Certificates of Deposit | Level 1 | Fair Value, Recurring |  |  |
Assets: |  |  |
Cash equivalents |  | 0 | 0
Certificates of Deposit | Level 2 | Fair Value, Recurring |  |  |
Assets: |  |  |
Cash equivalents |  | 40,954,000 | 74,502,000
Certificates of Deposit | Level 3 | Fair Value, Recurring |  |  |
Assets: |  |  |
Cash equivalents |  | $ 0 | $ 0

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