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Available for Sale Debt Securities - Narrative (Details) - USD ($)
12 Months Ended
Jun. 02, 2021
Aug. 07, 2020
Apr. 05, 2019
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Debt and Equity Securities, FV-NI [Line Items]            
Purchase of available for sale debt securities       $ 70,441,000 $ 0 $ 125,121,000
MorphoSys | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement            
Debt and Equity Securities, FV-NI [Line Items]            
Payment of capital $ 350,000,000          
Maximum commitment to fund collaborative arrangement $ 150,000,000     $ 150,000,000    
Period of return 9 years          
Period of return start date 2 years          
Debt Securities            
Debt and Equity Securities, FV-NI [Line Items]            
Purchase of available for sale debt securities     $ 125,000,000      
Series B Preferred Shares            
Debt and Equity Securities, FV-NI [Line Items]            
Purchase of available for sale debt securities   $ 200,000,000        
Preferred Shares | Debt Securities            
Debt and Equity Securities, FV-NI [Line Items]            
Number of shares purchased (in shares)     2,495      
Price per share (in USD per share)     $ 50,100      
Redemption price, percentage     200.00%      
Redemption default, interest rate     18.00%      
Default period     1 year      
Preferred Shares | Series B Preferred Shares            
Debt and Equity Securities, FV-NI [Line Items]            
Number of shares purchased (in shares)   3,992   1,406    
Price per share (in USD per share)   $ 50,100        
Redemption default, interest rate   18.00%        
Redemption default, threshold period   1 year        
Preferred Shares | Redemption, Period One | Maximum            
Debt and Equity Securities, FV-NI [Line Items]            
Redemption price, percentage     200.00%      
Preferred Shares | Redemption, Period One | Debt Securities | Maximum            
Debt and Equity Securities, FV-NI [Line Items]            
Redemption price, percentage     200.00%      
Preferred Shares | Redemption, Period One | Series B Preferred Shares            
Debt and Equity Securities, FV-NI [Line Items]            
Redemption price, percentage   180.00%   180.00%    
Preferred Shares | Redemption, Period Two | Debt Securities            
Debt and Equity Securities, FV-NI [Line Items]            
Redemption price, percentage     200.00%      
Preferred Shares | Redemption, Period Two | Series B Preferred Shares            
Debt and Equity Securities, FV-NI [Line Items]            
Redemption price, percentage   180.00%