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Available for Sale Debt Securities - Narrative (Details)
$ / shares in Units, $ in Thousands
 1 Months Ended 3 Months Ended 12 Months Ended
Oct. 03, 2022
Jan. 07, 2022
USD ($)
tranche
Jun. 02, 2021
USD ($)
Aug. 07, 2020
USD ($)
$ / shares
shares
Apr. 05, 2019
USD ($)
$ / shares
shares
Sep. 30, 2022
USD ($)
Feb. 29, 2020
Mar. 31, 2021
USD ($)
Dec. 31, 2022
USD ($)
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Debt and Equity Securities, FV-NI [Line Items]                      
Long term funding partnership, amount   $ 300,000                  
Long term funding partnership, number of tranches | tranche   5                  
Long term funding partnership, initial payment   $ 50,000                  
Required amount to be drawn   50,000                  
Long term funding partnership, additional payments, aggregate amount   $ 200,000             $ 200,000    
Interest free and payment free period, calendar quarters, tranche one | tranche   6                  
Interest free and payment free period, calendar quarters, tranche two | tranche   34                  
Installment repayments, percentage of amount drawn   1.9                  
Long term funding partnership, total amount drawn   2.0                  
Long term funding partnership, expected payment                 125,000    
Purchase of available for sale debt securities                 479,559 $ 70,441 $ 0
Reclassification of unrealized gains on available for sale debt securities                 53,432 50,896 20,551
Realized gain on available for sale securities                 $ (6,815) 17,859 18,600
MorphoSys                      
Debt and Equity Securities, FV-NI [Line Items]                      
Maximum commitment to fund collaborative arrangement                   150,000  
Redemption price, percentage                 2.2    
MorphoSys | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement                      
Debt and Equity Securities, FV-NI [Line Items]                      
Payment of capital     $ 350,000                
Maximum commitment to fund collaborative arrangement     $ 150,000     $ 150,000     $ 150,000    
Period of return                 9 years    
Development fund bond                      
Debt and Equity Securities, FV-NI [Line Items]                      
Maximum commitment to fund collaborative arrangement           $ 300,000          
Series A Preferred Stock                      
Debt and Equity Securities, FV-NI [Line Items]                      
Purchase of available for sale debt securities         $ 125,000            
Proceeds from redemption of preferred shares               $ 15,600      
Series B Preferred Shares                      
Debt and Equity Securities, FV-NI [Line Items]                      
Purchase of available for sale debt securities       $ 200,000              
Preferred Shares | Series A Preferred Stock                      
Debt and Equity Securities, FV-NI [Line Items]                      
Number of shares purchased (in shares) | shares         2,495            
Price per share (in dollars per share) | $ / shares         $ 50,100            
Preferred Shares | Series B Preferred Shares                      
Debt and Equity Securities, FV-NI [Line Items]                      
Number of shares purchased (in shares) | shares       3,992              
Price per share (in dollars per share) | $ / shares       $ 50,100              
Realized gain on available for sale securities                 $ 122,500 $ 13,500 $ 18,600
Preferred Shares | Redemption, Period One | Series A Preferred Stock                      
Debt and Equity Securities, FV-NI [Line Items]                      
Redemption price, percentage             2        
Preferred Shares | Redemption, Period Two | Series A Preferred Stock                      
Debt and Equity Securities, FV-NI [Line Items]                      
Redemption price, percentage 2                    
Preferred Shares | Redemption, Period Two | Series B Preferred Shares                      
Debt and Equity Securities, FV-NI [Line Items]                      
Redemption price, percentage 1.8