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Balance Sheet Information - Supplemental Balance Sheet Information (Details) - USD ($)
$ in Millions
Dec. 31, 2019
Dec. 31, 2018
Inventories:    
Raw materials $ 138.4 $ 137.3
Work in process 772.9 760.7
Finished goods 321.1 327.2
Inventories, net 1,232.4 1,225.2
Property, plant and equipment, net:    
Land 125.2 125.5
Buildings 860.6 820.4
Machinery and equipment 4,275.2 3,980.2
Property, plant and equipment, gross 5,261.0 4,926.1
Less: Accumulated depreciation (2,669.4) (2,376.5)
Property, plant and equipment, net 2,591.6 2,549.6
Accrued expenses:    
Accrued payroll and related benefits 153.4 240.8
Sales related reserves 247.3 294.8
Income taxes payable 22.5 38.2
Other 115.6 85.3
Accrued expenses $ 538.8 $ 659.1