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Balance Sheet Information - Supplemental Balance Sheet Information (Details) - USD ($)
$ in Millions
Dec. 31, 2020
Dec. 31, 2019
Inventories:    
Raw materials $ 135.7 $ 138.4
Work in process 829.7 772.9
Finished goods 286.0 321.1
Inventories, net 1,251.4 1,232.4
Property, plant and equipment, net:    
Property, plant and equipment, gross 5,507.7 5,261.0
Less: Accumulated depreciation (2,995.4) (2,669.4)
Property, plant and equipment, net 2,512.3 2,591.6
Accrued expenses:    
Accrued payroll and related benefits 166.8 153.4
Sales related reserves 233.3 247.3
Income taxes payable 25.5 22.5
Other 144.4 115.6
Accrued expenses 570.0 538.8
Land    
Property, plant and equipment, net:    
Property, plant and equipment, gross 119.7 125.2
Buildings    
Property, plant and equipment, net:    
Property, plant and equipment, gross 850.0 860.6
Machinery and equipment    
Property, plant and equipment, net:    
Property, plant and equipment, gross $ 4,538.0 $ 4,275.2