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Property, Plant and Equipment (Details Textual) (USD $) In Millions, unless otherwise specified | 12 Months Ended |  | 12 Months Ended
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Dec. 31, 2013 | Dec. 31, 2012 | Dec. 31, 2011 | Dec. 31, 2013 Cambridge Leases | Dec. 31, 2012 Cambridge Leases | Dec. 31, 2011 Cambridge Leases | Dec. 31, 2013 Hillerod Denmark Facility | Sep. 30, 2013 Hillerod Denmark Facility | Dec. 31, 2013 Eisai
Property, Plant and Equipment |  |  |  |  |  |  |  |  |
Depreciation expense | $ 187.8 | $ 164.3 | $ 143.9 | $ 6.2 | $ 11.4 | $ 4.7 |  |  |
Interest cost capitalization related to construction in progress | 7.8 | 25.4 | 32.6 |  |  |  |  |  |
Derecognition of construction in progress assets |  |  |  | 161.5 |  |  |  |  |
Construction cost incurred not yet paid |  |  |  |  | 86.5 |  |  |  |
Charges recognized to vacate building |  |  |  | 27.2 |  |  |  |  |
Total cost | $ 2,869.0 | $ 2,683.3 |  |  |  |  |  | $ 465.9 |
Average estimated useful life |  |  |  |  |  |  | 20 years |  |
Term of lease |  |  |  | 15 years |  |  |  |  | 10 years
Cancellation Period of Lease |  |  |  |  |  |  |  |  | 5 years

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- Definition The amount of expense recognized in the current period that reflects the allocation of the cost of tangible assets over the assets' useful lives. Includes production and non-production related depreciation. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3602-108585 + Details
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