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Intangible Assets and Goodwill (Tables)
 3 Months Ended
Mar. 31, 2014
Goodwill and Intangible Assets Disclosure [Abstract]  
Intangible assets
Intangible assets, net of accumulated amortization, impairment charges and adjustments, are summarized as follows:
 
 
 
As of March 31, 2014
 
As of December 31, 2013
(In millions)
Estimated
Life
 
Cost
 
Accumulated
Amortization
 
Net
 
Cost
 
Accumulated
Amortization
 
Net
Out-licensed patents
13-23 years
 
$
543.3

 
$
(458.3
)
 
$
85.0

 
$
578.0

 
$
(450.8
)
 
$
127.2

Developed 
technology
15-23 years
 
3,005.3

 
(2,224.3
)
 
781.0

 
3,005.3

 
(2,165.4
)
 
839.9

In-process research and development
Indefinite until commercialization
 
330.9

 
—

 
330.9

 
327.4

 
—

 
327.4

Trademarks and 
tradenames
Indefinite
 
64.0

 
—

 
64.0

 
64.0

 
—

 
64.0

Acquired and in-licensed rights 
and patents
6-17 years
 
3,269.6

 
(166.2
)
 
3,103.4

 
3,240.0

 
(123.8
)
 
3,116.2

Total intangible assets
 
 
$
7,213.1

 
$
(2,848.8
)
 
$
4,364.4

 
$
7,214.7

 
$
(2,740.0
)
 
$
4,474.7
Estimated future amortization for acquired intangible assets
Based upon this more recent analysis, the estimated future amortization for acquired intangible assets is expected to be as follows:
(In millions)
As of March 31, 2014
2014 (remaining nine months)
$
316.3

2015
334.7

2016
319.9

2017
323.2

2018
324.3

2019
304.1

Total
$
1,922.5
Summary of roll forward of the changes in goodwill
The following table provides a roll forward of the changes in our goodwill balance:
(In millions)
As of
March 31,
2014
 
As of
December 31,
2013
Goodwill, beginning of period
$
1,232.9

 
$
1,201.3

Increase to goodwill
—

 
35.7

Other
—

 
(4.1
)
Goodwill, end of period
$
1,232.9

 
$
1,232.9