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Condensed Consolidated Statements of Cash Flows (Unaudited) (USD $) In Thousands, unless otherwise specified | 9 Months Ended
--- | ---
Sep. 30, 2014 | Sep. 30, 2013
Cash flows from operating activities: |  |
Net income | $ 2,058,980 | $ 1,405,035
Adjustments to reconcile net income to net cash flows from operating activities: |  |
Depreciation and amortization | 530,508 | 373,357
Share-based compensation | 119,508 | 104,851
Deferred income taxes | (229,273) | (166,187)
Other | (95,711) | (36,577)
Changes in operating assets and liabilities, net: |  |
Accounts receivable | (297,057) | (219,860)
Inventory | (119,890) | (182,814)
Accrued expenses and other current liabilities | 19,283 | 110,794
Other changes in operating assets and liabilities, net | 22,904 | 87,474
Net cash flows provided by operating activities | 2,009,252 | 1,476,073
Cash flows from investing activities: |  |
Proceeds from sales and maturities of marketable securities | 1,942,871 | 5,025,218
Purchases of marketable securities | (2,738,584) | (2,473,609)
Acquisition of TYSABRI rights | 0 | (3,262,719)
Purchases of property, plant and equipment | (180,854) | (167,628)
Contingent consideration related to Fumapharm AG acquisition | (175,000) | 0
Other | (13,131) | (15,954)
Net cash flows used in investing activities | (1,164,698) | (894,692)
Cash flows from financing activities: |  |
Purchase of treasury stock | (359,981) | (400,308)
Proceeds from issuance of stock for share-based compensation arrangements | 44,960 | 56,367
Repayment of borrowings under senior notes and other debt | (2,674) | (452,340)
Excess tax benefit from stock options | 90,423 | 67,902
Other | (15,336) | 670
Net cash flows used in financing activities | (242,608) | (727,709)
Net increase (decrease) in cash and cash equivalents | 601,946 | (146,328)
Effect of exchange rate changes on cash and cash equivalents | (18,227) | 3,418
Cash and cash equivalents, beginning of the period | 602,562 | 570,721
Cash and cash equivalents, end of the period | $ 1,186,281 | $ 427,811

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- Definition The aggregate amount of noncash, equity-based employee remuneration. This may include the value of stock or unit options, amortization of restricted stock or units, and adjustment for officers' compensation. As noncash, this element is an add back when calculating net cash generated by operating activities using the indirect method. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3602-108585 + Details
Name: | us-gaap_ShareBasedCompensation
Namespace Prefix: | us-gaap_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration