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Investments in Variable Interest Entities (Details) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended |
--- | --- | --- | ---
Sep. 30, 2015 | Sep. 30, 2014 | Sep. 30, 2015 | Sep. 30, 2014 | Dec. 31, 2014
Variable Interest Entity [Line Items] |  |  |  |  |
Net income (loss) attributable to noncontrolling interests, net of tax | $ 53,871 | $ (738) | $ 49,053 | $ 7,660 |
Investment in Variable Interest Entities (Textual) [Abstract] |  |  |  |  |
Research and development | 519,863 | 417,174 | 1,471,140 | 1,393,331 |
Investment in biotechnology companies that are determined to be unconsolidated variable interest entities | 10,700 |  | 10,700 |  | $ 7,900
Neurimmune |  |  |  |  |
Variable Interest Entity [Line Items] |  |  |  |  |
Net income (loss) attributable to noncontrolling interests, net of tax |  |  | 60,000 |  |
Investment in Variable Interest Entities (Textual) [Abstract] |  |  |  |  |
Remaining potential development milestone payments and royalties on commercial sales under the terms of collaboration agreement |  |  | 275,000 |  |
Research and development | $ 39,700 | $ 7,400 | $ 87,500 | $ 29,100 |

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- Definition Investment in biotechnology companies that are determined to be unconsolidated variable interest entities. + References No definition available. + Details
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- Definition Investment in Variable Interest Entities. + References No definition available. + Details
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- Definition Expected total payments including upfront and milestone payments as well as the greater of an annual maintenance fee or usage-based royalty payments under the terms of collaboration agreement. + References No definition available. + Details
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- Definition Amount of Net Income (Loss) attributable to noncontrolling interest. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 810 -SubTopic 10 -Section 55 -Paragraph 4J -URI http://asc.fasb.org/extlink&oid=35736750&loc=SL4591551-111686 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 810 -SubTopic 10 -Section 50 -Paragraph 1A -URI http://asc.fasb.org/extlink&oid=18733093&loc=SL4573702-111684 + Details
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- Definition The costs incurred in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, excluding in-process research and development acquired in a business combination consummated during the period. Excludes software research and development, which has a separate concept. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 730 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6420194&loc=d3e21568-108373 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Research and Development -URI http://asc.fasb.org/extlink&oid=6523717 + Details
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References No definition available. + Details
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