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Intangible Assets and Goodwill (Tables)
 12 Months Ended
Dec. 31, 2015
Goodwill and Intangible Assets Disclosure [Abstract]  
Intangible assets
 
 
 
As of December 31, 2015
 
As of December 31, 2014
(In millions)
Estimated Life
 
Cost
 
Accumulated
Amortization
 
Net
 
Cost
 
Accumulated
Amortization
 
Net
Out-licensed patents
13-23 years
 
$
543.3

 
$
(506.0
)
 
$
37.3

 
$
543.3

 
$
(481.7
)
 
$
61.6

Developed technology
15-23 years
 
3,005.3

 
(2,552.9
)
 
452.4

 
3,005.3

 
(2,396.8
)
 
608.5

In-process research and development
Indefinite until commercialization
 
730.5

 
—

 
730.5

 
314.1

 
—

 
314.1

Trademarks and tradenames
Indefinite
 
64.0

 
—

 
64.0

 
64.0

 
—

 
64.0

Acquired and in-licensed rights and patents
6-18 years
 
3,303.2

 
(502.3
)
 
2,800.9

 
3,280.4

 
(300.1
)
 
2,980.3

Total intangible assets
 
 
$
7,646.3

 
$
(3,561.2
)
 
$
4,085.1

 
$
7,207.1

 
$
(3,178.6
)
 
$
4,028.5
Estimated future amortization of intangible assets
(In millions)
As of December 31, 2015
2016
$
346.4

2017
318.6

2018
291.0

2019
275.1

2020
269.1

Total
$
1,500.2
Summary of roll forward of the changes in goodwill
 
As of December 31,
(In millions)
2015
 
2014
Goodwill, beginning of year
$
1,760.2

 
$
1,232.9

Increase to goodwill
908.1

 
527.3

Other
(4.5
)
 
—

Goodwill, end of year
$
2,663.8

 
$
1,760.2