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Intangible Assets and Goodwill (Tables) | 6 Months Ended
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Jun. 30, 2016
Goodwill and Intangible Assets Disclosure [Abstract] |
Intangible assets | Intangible assets, net of accumulated amortization, impairment charges and adjustments, are summarized as follows:
|  |  | As of June 30, 2016 |  | As of December 31, 2015
(In millions) | Estimated Life |  | Cost |  | Accumulated Amortization |  | Net |  | Cost |  | Accumulated Amortization |  | Net
Out-licensed patents | 13-23 years |  | $ | 543.3 |  |  | $ | (514.9 | ) |  | $ | 28.4 |  |  | $ | 543.3 |  |  | $ | (506.0 | ) |  | $ | 37.3 |
Developed technology | 15-23 years |  | 3,005.3 |  |  | (2,604.5 | ) |  | 400.8 |  |  | 3,005.3 |  |  | (2,552.9 | ) |  | 452.4 |
In-process research and development | Indefinite until commercialization |  | 692.3 |  |  | — |  |  | 692.3 |  |  | 730.5 |  |  | — |  |  | 730.5 |
Trademarks and tradenames | Indefinite |  | 64.0 |  |  | — |  |  | 64.0 |  |  | 64.0 |  |  | — |  |  | 64.0 |
Acquired and in-licensed rights and patents | 6-18 years |  | 3,405.4 |  |  | (623.3 | ) |  | 2,782.1 |  |  | 3,303.2 |  |  | (502.3 | ) |  | 2,800.9 |
Total intangible assets |  |  | $ | 7,710.3 |  |  | $ | (3,742.7 | ) |  | $ | 3,967.6 |  |  | $ | 7,646.3 |  |  | $ | (3,561.2 | ) |  | $ | 4,085.1 |
Estimated future amortization for acquired intangible assets | Based upon this analysis, the estimated future amortization of acquired intangible assets for the next five years is expected to be as follows:
(In millions) | As of June 30, 2016
2016 (remaining six months) | $ | 181.6 |
2017 | 325.1 |
2018 | 298.2 |
2019 | 282.7 |
2020 | 277.1 |
2021 | 265.0 |
Summary of roll forward of the changes in goodwill | The following table provides a roll forward of the changes in our goodwill balance:
(In millions) | As of June 30, 2016
Goodwill, beginning of period | $ | 2,663.8 |
Increase to goodwill | 515.0 |
Other | (11.7 | )
Goodwill, end of period | $ | 3,167.1 |

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- Definition Tabular disclosure of goodwill by reportable segment and in total which includes a rollforward schedule. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -SubTopic 20 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=35741047&loc=d3e13816-109267 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -SubTopic 20 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=35741047&loc=d3e13854-109267 + Details
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- Definition Tabular disclosure of the amount of amortization expense expected to be recorded in succeeding fiscal years for finite-lived intangible assets. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -SubTopic 30 -Section 50 -Paragraph 2 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=66006027&loc=d3e16323-109275 + Details
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