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Property, Plant and Equipment (Details Textual) - USD ($) $ in Millions | 3 Months Ended | 12 Months Ended
--- | --- | ---
Mar. 31, 2016 | Sep. 30, 2015 | Dec. 31, 2016 | Dec. 31, 2015 | Dec. 31, 2014
Property, Plant and Equipment |  |  |  |  |
Depreciation expense |  |  | $ 309.3 | $ 217.9 | $ 198.4
Interest cost capitalization related to construction in progress |  |  | 12.9 | 10.4 | $ 6.4
Construction in progress |  |  | 658.6 | 441.2 |
Solothurn |  |  |  |  |
Property, Plant and Equipment |  |  |  |  |
Construction in progress |  |  | 481.5 | 99.0 |
Eisai |  |  |  |  |
Property, Plant and Equipment |  |  |  |  |
Facility Purchase |  | $ 104.8 |  |  |
Term of original lease |  | 10 years |  |  |
Term of amended lease |  | 3 years |  |  |
Capital lease obligation |  | $ 20.3 | $ 18.1 | $ 19.8 |
Building | Eisai |  |  |  |  |
Property, Plant and Equipment |  |  |  |  |
Facility Purchase |  | 58.6 |  |  |
Machinery and Equipment | Eisai |  |  |  |  |
Property, Plant and Equipment |  |  |  |  |
Facility Purchase |  | 25.9 |  |  |
Land | Eisai |  |  |  |  |
Property, Plant and Equipment |  |  |  |  |
Facility Purchase |  | $ 20.3 |  |  |
Swiss francs | Land | Solothurn |  |  |  |  |
Property, Plant and Equipment |  |  |  |  |
Facility Purchase | $ 64.4 |  |  |  |
United States of America, Dollars | Land | Solothurn |  |  |  |  |
Property, Plant and Equipment |  |  |  |  |
Facility Purchase | $ 62.5 |  |  |  |

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- Definition Amount equal to the present value (the principal) at the beginning of the lease term of minimum lease payments during the lease term (excluding that portion of the payments representing executory costs such as insurance, maintenance, and taxes to be paid by the lessor, together with any profit thereon) net of payments or other amounts applied to the principal through the balance sheet date. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 840 -SubTopic 30 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=6455398&loc=d3e45280-112737 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(22)) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 944 -SubTopic 210 -Section S99 -Paragraph 1 -Subparagraph (SX 210.7-03(a)(16)) -URI http://asc.fasb.org/extlink&oid=6879938&loc=d3e572229-122910 + Details
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- Definition Amount of structure or a modification to a structure under construction. Includes recently completed structures or modifications to structures that have not been placed into service. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229 + Details
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