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Other Consolidated Financial Statement Detail (Details) - USD ($)
$ in Millions
 12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Revenue-related reserves for discounts and allowances $ 605.5 $ 662.7 $ 483.8 $ 426.2
Cash Paid During the Year        
Interest 281.2 39.1 41.2  
Income taxes 1,642.2 1,674.8 1,163.2  
Other Nonoperating Income (Expense) [Abstract]        
Interest income 63.4 22.1 12.2  
Interest expense 260.0 95.5 29.5  
Gain (loss) on investments, net 6.0 (3.8) 11.8  
Foreign exchange gains (losses), net (9.8) (32.7) (11.6)  
Other, net (17.0) (13.8) (8.7)  
Total other income (expense), net (217.4) (123.7) $ (25.8)  
Accrued Liabilities, Current [Abstract]        
Current portion of contingent consideration obligations 580.8 504.7    
Accrued TECFIDERA litigation settlement and license charges 454.8 0.0    
Employee compensation and benefits 282.9 270.8    
Royalties and licensing fees 195.8 167.9    
Accrued construction in progress 134.0 87.9    
Collaboration expenses 130.9 31.2    
Other 685.7 516.2    
Accrued expenses and other 2,903.5 2,096.8    
Component of accrued expenses and other        
Revenue-related reserves for discounts and allowances $ 438.6 $ 518.1