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Other Consolidated Financial Statement Detail (Details) - USD ($)
$ in Millions
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Revenue-related reserves for discounts and allowances $ 761.6 $ 605.5 $ 662.7 $ 483.8
Cash Paid During the Year        
Interest 281.7 281.2 39.1  
Income taxes 1,066.4 1,642.2 1,674.8  
Other Nonoperating Income (Expense) [Abstract]        
Interest income 78.5 63.4 22.1  
Interest expense 250.8 260.0 95.5  
Gain (loss) on investments, net (36.3) 6.0 (3.8)  
Foreign exchange gains (losses), net 6.3 (9.8) (32.7)  
Other income (expense) (13.1) (17.0) (13.8)  
Total other income (expense), net (215.4) (217.4) $ (123.7)  
Accrued Liabilities, Current [Abstract]        
Current portion of contingent consideration obligations 844.6 580.8    
Employee compensation and benefits 297.7 282.9    
Royalties and licensing fees 206.7 195.8    
Collaboration expenses 183.7 130.9    
Accrued construction in progress 159.7 134.0    
Accrued TECFIDERA litigation settlement and license charges 0.0 454.8    
Other 636.9 685.7    
Accrued expenses and other 2,901.3 2,903.5    
Component of accrued expenses and other        
Revenue-related reserves for discounts and allowances $ 572.0 $ 438.6