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Intangible Assets and Goodwill (Tables) | 12 Months Ended
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Dec. 31, 2019
Goodwill and Intangible Assets Disclosure [Abstract] |
Intangible assets | Intangible assets, net of accumulated amortization, impairment charges and adjustments are summarized as follows:
|  |  | As of December 31, 2019 |  | As of December 31, 2018
(In millions) | Estimated Life |  | Cost |  | Accumulated Amortization |  | Net |  | Cost |  | Accumulated Amortization |  | Net
Completed technology | 4-28 years |  | $ | 7,379.3 |  |  | $ | (4,881.4 | ) |  | $ | 2,497.9 |  |  | $ | 7,187.3 |  |  | $ | (4,607.3 | ) |  | $ | 2,580.0 |
In-process research and development | Indefinite until commercialization |  | 965.5 |  |  | — |  |  | 965.5 |  |  | 476.0 |  |  | — |  |  | 476.0 |
Trademarks and trade names | Indefinite |  | 64.0 |  |  | — |  |  | 64.0 |  |  | 64.0 |  |  | — |  |  | 64.0 |
Total intangible assets |  |  | $ | 8,408.8 |  |  | $ | (4,881.4 | ) |  | $ | 3,527.4 |  |  | $ | 7,727.3 |  |  | $ | (4,607.3 | ) |  | $ | 3,120.0 |
Estimated future amortization of intangible assets | Based upon this most recent analysis, the estimated future amortization of acquired intangible assets for the next five years is expected to be as follows:
(In millions) | As of December 31, 2019
2020 | $ | 260.0 |
2021 | 220.0 |
2022 | 225.0 |
2023 | 230.0 |
2024 | 220.0 |
Summary of roll forward of the changes in goodwill | The following table provides a roll forward of the changes in our goodwill balance:
| As of December 31,
(In millions) | 2019 |  | 2018
Goodwill, beginning of year | $ | 5,706.4 |  |  | $ | 4,632.5 |
Increase to goodwill | 117.5 |  |  | 1,080.1 |
Elimination of goodwill allocated to Hillerød, Denmark manufacturing operations | (69.5 | ) |  | — |
Other | 3.4 |  |  | (6.2 | )
Goodwill, end of year | $ | 5,757.8 |  |  | $ | 5,706.4 |

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