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Other Consolidated Financial Statement Detail (Details) - USD ($)
$ in Millions
 12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Equity Securities, FV-NI, Gain (Loss) $ 200.1 $ 127.9 $ (19.8)  
Equity Securities, FV-NI, Realized Gain (Loss) 50.0 (0.6) 0.0  
Equity Securities, FV-NI, Unrealized Gain (Loss) 150.1 128.5 (19.8)  
Cash Paid During the Year        
Interest 244.2 243.2 281.7  
Income taxes 1,064.5 1,007.1 1,066.4  
Other Nonoperating Income (Expense) [Abstract]        
Interest income 120.0 112.5 78.5  
Interest expense 187.4 200.6 250.8  
Gain (loss) on investments, net 204.7 119.5 (36.3)  
Foreign exchange gains (losses), net (7.0) (9.9) 6.3  
Other income (expense) (47.0) (10.5) (14.7)  
Total other income (expense), net 83.3 11.0 (217.0)  
Accrued Liabilities, Current [Abstract]        
Revenue related reserves for discounts and allowances 1,198.9 1,051.3 $ 761.6 $ 605.5
Employee compensation and benefits 309.1 320.9    
Collaboration expenses 281.6 261.6    
Royalties and licensing fees 220.9 224.7    
Current portion of contingent consideration obligations 148.4 444.8    
Accrued construction in progress 78.0 125.2    
Other 726.7 609.3    
Accrued expenses and other 2,765.8 2,861.2    
Other Current Liabilities        
Accrued Liabilities, Current [Abstract]        
Revenue related reserves for discounts and allowances $ 1,001.1 $ 874.7