Intangible Assets and Goodwill (Tables)

12 Months Ended

Dec. 31, 2019

Goodwill and Intangible Assets Disclosure [Abstract]

Intangible assets, net of accumulated amortization, impairment charges and adjustments are summarized as follows:



		As of December 31, 2019							As of December 31, 2018
(In millions)	Estimated Life	Cost		Accumulated Amortization			Net		Cost		Accumulated Amortization			Net
Completed technology	4-28 years	$	7,379.3	$	(4,881.4	)	$	2,497.9	$	7,187.3	$	(4,607.3	)	$	2,580.0
In-process research and development	Indefinite until commercialization	965.5		—			965.5		476.0		—			476.0
Trademarks and trade names	Indefinite	64.0		—			64.0		64.0		—			64.0
Total intangible assets		$	8,408.8	$	(4,881.4	)	$	3,527.4	$	7,727.3	$	(4,607.3	)	$	3,120.0

Estimated future amortization of intangible assets

Based upon this most recent analysis, the estimated future amortization of acquired intangible assets for the next five years is expected to be as follows:



(In millions)	As of December 31, 2019
2020	$	260.0
2021	220.0
2022	225.0
2023	230.0
2024	220.0

Summary of roll forward of the changes in goodwill

The following table provides a roll forward of the changes in our goodwill balance:



	As of December 31,
(In millions)	2019			2018
Goodwill, beginning of year	$	5,706.4		$	4,632.5
Increase to goodwill	117.5			1,080.1
Elimination of goodwill allocated to Hillerød, Denmark manufacturing operations	(69.5		)	—
Other	3.4			(6.2		)
Goodwill, end of year	$	5,757.8		$	5,706.4