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Collaborative and Other Relationships - Alkermes (Details) - USD ($)
$ in Millions
1 Months Ended 12 Months Ended
Oct. 31, 2019
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Collaborative arrangements and non-collaborative arrangement transactions        
Research and development   $ 3,990.9 $ 2,280.6 $ 2,597.2
Potential future milestone payments commitment to third party approximately   10,200.0    
Alkermes        
Collaborative arrangements and non-collaborative arrangement transactions        
Research and development   $ 32.4 53.5 $ 68.7
Potential future milestone payments commitment to third party approximately     $ 155.0  
VUMERITY | Alkermes        
Collaborative arrangements and non-collaborative arrangement transactions        
Percentage of royalties as per collaboration 15.00% 15.00%    
Royalties payable period, post FDA approval   5 years