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Intangible Assets and Goodwill (Tables)
12 Months Ended
Dec. 31, 2020
Goodwill and Intangible Assets Disclosure [Abstract]  
Intangible assets
Intangible assets, net of accumulated amortization, impairment charges and adjustments are summarized as follows:
  As of December 31, 2020As of December 31, 2019
(In millions)Estimated LifeCostAccumulated
Amortization
NetCostAccumulated
Amortization
Net
Completed technology4-28 years$7,394.3 $(5,136.5)$2,257.8 $7,379.3 $(4,881.4)$2,497.9 
In-process research and developmentIndefinite until commercialization762.5 — 762.5 965.5 — 965.5 
Trademarks and trade namesIndefinite64.0 — 64.0 64.0 — 64.0 
Total intangible assets$8,220.8 $(5,136.5)$3,084.3 $8,408.8 $(4,881.4)$3,527.4 
Estimated future amortization of intangible assets
The estimated future amortization of finite-lived intangible assets for the next five years is expected to be as follows:
(In millions)As of December 31, 2020
2021$205.0 
2022215.0 
2023215.0 
2024225.0 
2025220.0 
Summary of roll forward of the changes in goodwill
The following table provides a roll forward of the changes in our goodwill balance:
 As of December 31,
(In millions)20202019
Goodwill, beginning of year$5,757.8 $5,706.4 
Increase to goodwill— 117.5 
Elimination of goodwill allocated to Hillerød, Denmark manufacturing operations— (69.5)
Other4.3 3.4 
Goodwill, end of year$5,762.1 $5,757.8