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Summary of Significant Accounting Policies - Narrative (Details)
$ in Millions
 9 Months Ended 12 Months Ended 24 Months Ended
Dec. 31, 2018
USD ($)
Dec. 31, 2020
USD ($)
product
segment
Dec. 31, 2019
USD ($)
product
Dec. 31, 2018
USD ($)
Dec. 31, 2020
USD ($)
Dec. 31, 2017
USD ($)
Property, Plant and Equipment [Line Items]            
Number of ophthalmolgy biosimilar products | product   2 2      
Interest in subsidiary (less than given percentage)   100.00%        
Operating lease assets   $ 433.3 $ 427.0   $ 433.3  
Present value of operating lease liabilities   $ 485.2 486.3   485.2  
Number of operating segments | segment   1        
Advertising costs   $ 111.8 79.2 $ 90.2    
Stockholders equity $ 13,031.6 10,686.1 $ 13,339.1 13,031.6 10,686.1 $ 12,598.1
Eisai            
Property, Plant and Equipment [Line Items]            
Capitalized inventory   $ 93.8     $ 93.8  
Percentage of future development costs related to Eisai 15.00% 45.00%     45.00%  
Cumulative Effect, Period of Adoption, Adjustment            
Property, Plant and Equipment [Line Items]            
Operating lease assets $ 463.0     463.0    
Present value of operating lease liabilities 526.0     526.0    
Stockholders equity           106.1
Minimum            
Property, Plant and Equipment [Line Items]            
Payment terms of accounts receivable arising from product sales   30 days        
Minimum | Computer Software and Hardware            
Property, Plant and Equipment [Line Items]            
Property, plant and equipment, useful life   3 years        
Maximum            
Property, Plant and Equipment [Line Items]            
Payment terms of accounts receivable arising from product sales   90 days        
Maximum | Computer Software and Hardware            
Property, Plant and Equipment [Line Items]            
Property, plant and equipment, useful life   5 years        
Deferred Income Tax Charge | Cumulative Effect, Period of Adoption, Adjustment            
Property, Plant and Equipment [Line Items]            
Stockholders equity           500.0
Retained Earnings | Cumulative Effect, Period of Adoption, Adjustment            
Property, Plant and Equipment [Line Items]            
Stockholders equity           $ 500.0
Deferred tax liability | Cumulative Effect, Period of Adoption, Adjustment            
Property, Plant and Equipment [Line Items]            
Stockholders equity $ 400.0     $ 400.0