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Derivative Instruments - Narrative (Details)
₩ in Billions
1 Months Ended 12 Months Ended
Nov. 30, 2018
USD ($)
Nov. 30, 2018
KRW (₩)
Dec. 31, 2020
USD ($)
Dec. 31, 2019
USD ($)
Dec. 31, 2018
USD ($)
Jun. 30, 2018
Feb. 29, 2012
Derivatives, Fair Value [Line Items]              
Range of durations of foreign currency forward contracts     24 months        
Payments to increase investment in Samsung Bioepis     $ 0 $ 0 $ 676,600,000    
Net gains (losses) of other income (expense) related to foreign currency forward contracts     $ (30,100,000) 5,900,000 2,000,000.0    
Samsung Bioepis              
Derivatives, Fair Value [Line Items]              
Samsung Bioepis, ownership percentage before additional purchase transaction           5.00%  
Samsung Bioepis, ownership percentage     49.90%       15.00%
Payments to increase investment in Samsung Bioepis $ 676,600,000 ₩ 759.5          
Net investment hedge              
Derivatives, Fair Value [Line Items]              
Forward contracts duration     10 months        
Derivative qualifying as hedge, excluded component, after tax     $ 200,000 2,900,000      
Designated as Hedging Instrument              
Derivatives, Fair Value [Line Items]              
Derivative, notional amount     3,229,700,000 1,892,400,000      
Not designated as hedging instrument              
Derivatives, Fair Value [Line Items]              
Derivative, notional amount     $ 1,158,000,000.0 793,800,000      
2.900% Senior Notes due September 15, 2020              
Derivatives, Fair Value [Line Items]              
Interest rate on senior notes     2.90%        
Foreign Exchange Forward              
Derivatives, Fair Value [Line Items]              
Unrealized gain (loss) on derivative instruments     $ 212,500,000 500,000 $ 27,300,000    
Foreign Exchange Forward | Net investment hedge              
Derivatives, Fair Value [Line Items]              
Unrealized gain (loss) on derivative instruments     21,200,000 $ 1,500,000      
Interest rate swap | Interest Expense              
Derivatives, Fair Value [Line Items]              
Gain (loss) on derivative instruments, net, pretax     3,300,000        
Interest rate swap | Designated as Hedging Instrument              
Derivatives, Fair Value [Line Items]              
Derivative, notional amount     $ 675,000,000.0        
Short-term derivative              
Derivatives, Fair Value [Line Items]              
Range of durations of foreign currency forward contracts     12 months        
Unrealized gain (loss) on derivative instruments     $ 175,200,000        
Minimum              
Derivatives, Fair Value [Line Items]              
Range of durations of foreign currency forward contracts     1 month 1 month      
Maximum              
Derivatives, Fair Value [Line Items]              
Range of durations of foreign currency forward contracts     24 months 15 months