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Fair Value Measurements (Details Textual) - USD ($) | 3 Months Ended |
--- | --- | ---
Mar. 31, 2021 | Dec. 31, 2020
Business Acquisition, Contingent Consideration [Line Items] |  |
Asset impairment charges | $ 0 |
Contingent consideration obligations | $ 226,000,000.0 | $ 110,300,000
Technological and Regulatory Success, Probability | 21.70% |
2.900% Senior Notes due 2020 |  |
Business Acquisition, Contingent Consideration [Line Items] |  |
Senior notes interest rate | 2.90% |
3.625% Senior Notes due 2022 |  |
Business Acquisition, Contingent Consideration [Line Items] |  |
Senior notes interest rate | 3.625% |
4.050% Senior Notes due 2025 |  |
Business Acquisition, Contingent Consideration [Line Items] |  |
Senior notes interest rate | 4.05% |
5.200% Senior Notes due 2045 |  |
Business Acquisition, Contingent Consideration [Line Items] |  |
Senior notes interest rate | 5.20% |

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