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v3.21.1

Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Millions | 3 Months Ended
--- | ---
Mar. 31, 2021 | Mar. 31, 2020
Cash flow from operating activities: |  |
Net income | $ 404.6 | $ 1,392.6
Adjustments to reconcile net income to net cash flows from operating activities: |  |
Depreciation, amortization and impairments | 146.9 | 119.9
Acquired in-process research and development | 0.0 | 75.0
Share-based compensation | 70.0 | 67.7
Contingent consideration | (33.8) | (4.6)
Deferred income taxes | (15.0) | 36.9
(Gain) loss on strategic investments | 437.6 | 62.0
Our share of Samsung Bioepis gains (losses) | 18.2 | 16.8
Other | 71.7 | 28.9
Changes in operating assets and liabilities, net: |  |
Accounts receivable | 37.2 | (238.4)
Due from anti-CD20 therapeutic programs | 43.8 | 78.6
Inventory | (112.5) | (62.2)
Accrued expense and other current liabilities | (283.6) | (347.4)
Income tax assets and liabilities | 64.8 | 223.0
Other changes in operating assets and liabilities, net | (80.9) | 18.5
Net cash flow provided by operating activities | 769.0 | 1,467.3
Cash flows from investing activities: |  |
Proceeds from sales and maturities of marketable securities | 819.2 | 2,389.3
Purchases of marketable securities | (913.3) | (1,684.7)
Proceeds from divestiture of Hillerød, Denmark manufacturing operations | 28.1 | 0.0
Purchases of property, plant and equipment | (92.6) | (149.7)
Acquired in-process research and development | 0.0 | (75.0)
Acquisitions of intangible assets | 0.0 | (37.0)
Proceeds from sales of strategic investments | 91.2 | 0.5
Other | 2.7 | (0.5)
Net cash flow (used in) provided by investing activities | (64.7) | 442.9
Cash flows from financing activities: |  |
Purchases of treasury stock | (600.0) | (2,220.2)
Payments related to issuance of stock for share-based compensation arrangements, net | (27.1) | (29.6)
Repayments of borrowings and premiums paid on debt exchange | (169.3) | 0.0
Other | 11.4 | 4.5
Net cash flow used in financing activities | (785.0) | (2,245.3)
Net increase (decrease) in cash and cash equivalents | (80.7) | (335.1)
Effect of exchange rate changes on cash and cash equivalents | 33.0 | (12.7)
Cash and cash equivalents, beginning of the period | 1,331.2 | 2,913.7
Cash and cash equivalents, end of the period | $ 1,217.5 | $ 2,591.3

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