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Other Consolidated Financial Statement (Details Textual) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Dec. 31, 2020
Class of Stock [Line Items]      
Gain (loss) on investments, net $ (436.6) $ (77.3)  
Other long-term liabilities 1,411.8   $ 1,329.6
Accrued income taxes 725.2   $ 709.9
Net gains recognized on the increase in fair value of equity securities (442.3) (60.9)  
Proceeds from sale of available-for-sale securities, equity 91.2 $ 0.5  
Ionis, Sangamo, Denali and Sage      
Class of Stock [Line Items]      
Net gains recognized on the increase in fair value of equity securities $ 442.0